Rufo Lorente Poyatos
A5089054268- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Biosimilars and Bioanalytical Methods
- Pregnancy and Medication Impact
- Endometriosis Research and Treatment
- Health, psychology, and well-being
- COVID-19 and Mental Health
- Autoimmune and Inflammatory Disorders
- Chronic Lymphocytic Leukemia Research
- Enhanced Recovery After Surgery
- Helicobacter pylori-related gastroenterology studies
- Empathy and Medical Education
- Stoma care and complications
- Uterine Myomas and Treatments
- Immunodeficiency and Autoimmune Disorders
- COVID-19 and healthcare impacts
Hospital General Universitario de Ciudad Real
2017-2024
(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe main epidemiological and clinical characteristics at diagnosis evolution disease, explore use drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 Spain were included followed-up for 1 year. (3) Results: We identified 3611 incident cases during 108 hospitals...
Crohn's disease (CD) varies by location, potentially affecting therapy efficacy and surgery risk, although research on this topic is conflicting. This study aims to investigate the independent association between CD location therapeutic patterns.
Markers that allow for the selection of tailored treatments individual patients with inflammatory bowel diseases (IBD) are yet to be identified. Our aim was describe trends in real-life treatment usage. For this purpose, from ENEIDA registry who received their first targeted IBD (biologics or tofacitinib) between 2015 and 2021 were included. A subsequent analysis Machine Learning models performed. The study included 10,009 [71% Crohn’s disease (CD) 29% ulcerative colitis (UC)]. In CD,...
Abstract Background Clinical trials and real-life studies with Ustekinumab in Crohn’s disease show its good efficacy safety profile. However, there are hardly any data on elderly patients, who excluded from these clinical trials. Our aim is to evaluate variables practice. Methods Retrospective analysis of patients the prospectively maintained ENEIDA registry treated for disease. Elderly were selected as those over 60 years old at start treatment. They compared 2 randomised controls same...
Background: Faecal calprotectin (FC) is a marker of gut inflammation that correlates with endoscopic activity in Crohn's disease (CD). However, its accuracy to predict postoperative recurrence remains be completely elucidated. We aim prospectively analyze if FC levels associate the presence and severity patients CD. The relationships between C-reactive protein (CRP) serum levels, clinical are also analyzed. Methods: A prospective multicentre observational study diagnostic was carried out 5...
Abstract Background Female sex has been associated with a worse response to anti-TNF drugs and discontinuation of these in immune-mediated diseases. Data Inflammatory Bowel Disease (IBD) are unclear. The aims study assess possible differences long-term treatment persistence safety biological between women men IBD. Methods Multicenter observational carried out data from the ENEIDA registry. Patients diagnosed Crohn's disease (CD) or ulcerative colitis (UC) who receive have received drugs, had...
Abstract Background It has been reported that familial aggregation occurs in 10–20% of inflammatory bowel disease (IBD) patients1. Familial IBD associated with anticipation2 and an increased need for immunosuppressants3 surgery4. However, most studies were performed before the widespread use biological agents this may impact on surgery. We aimed to compare clinical outcomes (by means therapy abdominal surgery) between sporadic forms era therapies. Methods Data extracted from ENEIDA registry...