Isha Puri

ORCID: 0000-0003-1001-2016
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Research Areas
  • COVID-19 Clinical Research Studies
  • Sepsis Diagnosis and Treatment
  • Renal Diseases and Glomerulopathies
  • Potassium and Related Disorders
  • Dialysis and Renal Disease Management
  • Intensive Care Unit Cognitive Disorders
  • Renal and Vascular Pathologies
  • Acute Kidney Injury Research
  • COVID-19 and healthcare impacts
  • Electrolyte and hormonal disorders
  • Complement system in diseases
  • Renal Transplantation Outcomes and Treatments
  • Renal function and acid-base balance
  • Chronic Kidney Disease and Diabetes
  • Muscle and Compartmental Disorders
  • Emergency and Acute Care Studies
  • Biliary and Gastrointestinal Fistulas
  • Gastrointestinal disorders and treatments
  • Neurological and metabolic disorders
  • Vasculitis and related conditions
  • Neurological Complications and Syndromes
  • Sarcoidosis and Beryllium Toxicity Research
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Abdominal vascular conditions and treatments
  • Liver Disease Diagnosis and Treatment

SUNY Downstate Health Sciences University
2019-2025

Kings County Hospital Center
2021-2025

State University of New York
2021-2025

New York City Health and Hospitals Corporation
2024

Texas Health Harris Methodist Hospital Fort Worth
2024

Robert Wood Johnson University Hospital
2023

Government Medical College
2021-2023

Johnson University
2020

Rutgers, The State University of New Jersey
2020

M.S. Ramaiah Medical College
2016

Significance Statement Although AKI is an important sequela of coronavirus disease 2019 (COVID-19), data on treated with RRT (AKI-RRT) in patients COVID-19 are limited. In a multicenter cohort study 3099 critically ill adults admitted to intensive care units (ICUs) at 67 hospitals across the United States, one five developed AKI-RRT, 63% whom died during hospitalization. Among who survived hospital discharge, three remained dependent and six 60 days after ICU admission. The identified...

10.1681/asn.2020060897 article EN Journal of the American Society of Nephrology 2020-10-16
Jennifer E. Flythe Magdalene M. Assimon Matthew J. Tugman Emily Chang Shruti Gupta and 95 more Jatan A. Shah Marie Anne Sosa Amanda D. Renaghan Michal L. Melamed F. Perry Wilson Javier A. Neyra Arash Rashidi Suzanne M. Boyle Shuchi Anand Marta Christov Leslie F. Thomas Daniel Edmonston David E. Leaf Carl P. Walther Samaya J. Anumudu Justin Arunthamakun Kathleen F. Kopecky Gregory P. Milligan Peter A. McCullough Thuy-Duyen Nguyen Shahzad Shaefi Megan L. Krajewski Sidharth Shankar Ameeka Pannu Juan D. Valencia Sushrut S. Waikar Zoé A. Kibbelaar Ambarish M. Athavale Peter Hart Shristi Upadhyay Ishaan Vohra Adam Green Jean-Sébastien Rachoin Christa Schorr Lisa Shea Daniel Edmonston Christopher L. Mosher Alexandre M. Shehata Zaza Cohen Valerie Allusson Gabriela Bambrick‐Santoyo Noor ul aain Bhatti Bijal Mehta Aquino Williams Samantha K. Brenner Patricia Walters Ronaldo C. Go Keith M. Rose Lili Chan Kusum S. Mathews Steven G. Coca Deena R. Altman Aparna Saha Howard Soh Huei Hsun Wen Sonali Bose Emily Leven Jing G. Wang Gohar Mosoyan Girish N. Nadkarni Pattharawin Pattharanitima Emily J. Gallagher Allon N. Friedman John Guirguis Rajat Kapoor Christopher Meshberger Katherine J. Kelly Chirag R. Parikh Brian T. Garibaldi Celia P. Corona‐Villalobos Yumeng Wen Steven Menez Rubab F. Malik Carmen Elena Cervantes Samir C. Gautam Mary C. Mallappallil Jie Ouyang Sabu John Ernie Yap Yohannes Adama Melaku Ibrahim Mohamed Siddhartha Bajracharya Isha Puri Mariah Thaxton Jyotsna Bhattacharya John E. Wagner Leon Boudourakis H. Bryant Nguyen Afshin Ahoubim Kianoush Kashani Shahrzad Tehranian Leslie F. Thomas Dheeraj Reddy Sirganagari Pramod Guru Yan Zhou

10.1053/j.ajkd.2020.09.003 article EN other-oa American Journal of Kidney Diseases 2020-09-19
Matthew M. Churpek Shruti Gupta A. Spicer William F. Parker John Fahrenbach and 95 more Samantha K. Brenner David E. Leaf Carl P. Walther Samaya J. Anumudu Justin Arunthamakun Kathleen F. Kopecky Gregory P. Milligan Peter A. McCullough Thuy-Duyen Nguyen Shahzad Shaefi Megan L. Krajewski Sidharth Shankar Ameeka Pannu Juan D. Valencia Sushrut S. Waikar Zoé A. Kibbelaar Ambarish M. Athavale Peter Hart Shristi Upadhyay Ishaan Vohra Adam Green Jean-Sébastien Rachoin Christa Schorr Lisa Shea Daniel Edmonston Christopher L. Mosher Alexandre M. Shehata Zaza Cohen Valerie Allusson Gabriela Bambrick‐Santoyo Noor ul aain Bhatti Bijal Mehta Aquino Williams Samantha K. Brenner Patricia Walters Ronaldo C. Go Keith M. Rose Miguel A. Hernán Lili Chan Kusum S. Mathews Steven G. Coca Deena R. Altman Aparna Saha Howard Soh Huei Hsun Wen Sonali Bose Emily Leven Jing G. Wang Gohar Mosoyan Girish N. Nadkarni Pattharawin Pattharanitima Emily J. Gallagher Allon N. Friedman John Guirguis Rajat Kapoor Christopher Meshberger Katherine Kelly Chirag R. Parikh Brian T. Garibaldi Celia P. Corona‐Villalobos Yumeng Wen Steven Menez Rubab F. Malik Elena Cervantes Samir C. Gautam Mary C. Mallappallil Jie Ouyang Sabu John Ernie Yap Yohannes Adama Melaku Ibrahim Mohamed Siddartha Bajracharya Isha Puri Mariah Thaxton Jyotsna Bhattacharya John E. Wagner Leon Boudourakis H. Bryant Nguyen Afshin Ahoubim Leslie F. Thomas Dheeraj Reddy Sirganagari Pramod Guru Kianoush Kashani Shahrzad Tehranian Yan Zhou Paul A. Bergl Jesús Rodríguez Jatan A. Shah Mrigank S. Gupta Princy Kumar Deepa G. Lazarous Seble Kassaye Michal L. Melamed Tanya S. Johns Ryan Mocerino

Rationale: Variation in hospital mortality has been described for coronavirus disease (COVID-19), but the factors that explain these differences remain unclear. Objective: Our objective was to use a large, nationally representative data set of critically ill adults with COVID-19 determine which variability. Methods: In this multicenter cohort study, we examined hospitalized ICUs at 70 U.S. hospitals between March and June 2020. The primary outcome 28-day mortality. We patient-level...

10.1164/rccm.202012-4547oc article EN cc-by-nc-nd American Journal of Respiratory and Critical Care Medicine 2021-04-23
Caroline M. Hsu Shruti Gupta Hocine Tighiouart Nitender Goyal Anthony J. Faugno and 95 more Asma Tariq Ritesh Raichoudhury Jill H. Sharma Leah Meyer Ravi K. Kshirsagar Aju Jose David E. Leaf Daniel E. Weiner Hsu Gupta Goyal Faugno Tariq Raichoudhury Sharma Meyer Kshirsagar Leaf Carl P. Walther Samaya J. Anumudu Justin Arunthamakun Kathleen F. Kopecky Gregory P. Milligan Peter A. McCullough Thuy-Duyen Nguyen Shahzad Shaefi Megan L. Krajewski Sidharth Shankar Ameeka Pannu Juan D. Valencia Kenneth A. Bauer Sushrut S. Waikar Zoé A. Kibbelaar Ambarish M. Athavale Peter Hart Shristi Upadhyay Ishaan Vohra Oyintayo Ajiboye Adam Green Jean-Sébastien Rachoin Christa Schorr Lisa Shea Daniel Edmonston Christopher L. Mosher Alexandre M. Shehata Zaza Cohen Valerie Allusson Gabriela Bambrick‐Santoyo Noor ul aain Bhatti Bijal Mehta Aquino WilliamsSamantha K. Brenner Patricia Walters Ronaldo C. Go Keith M. Rose Miguel A. Hernán Amy M. Zhou Ethan C. Kim Rebecca Lisk Lili Chan Kusum S. Mathews Steven G. Coca Deena R. Altman Aparna Saha Howard Soh Huei Hsun Wen Sonali Bose Emily Leven Jing G. Wang Gohar Mosoyan Pattharawin Pattharanitima Emily J. Gallagher Allon N. Friedman John Guirguis Rajat Kapoor Christopher Meshberger Katherine J. Kelly Chirag R. Parikh Brian T. Garibaldi Celia P. Corona‐Villalobos Yumeng Wen Steven Menez Rubab F. Malik Carmen Elena Cervantes Samir C. Gautam Mary C. Mallappallil Jie Ouyang Sabu John Ernie Yap Yohannes Adama Melaku Ibrahim Mohamed Siddhartha Bajracharya Isha Puri Mariah Thaxton Jyotsna Bhattacharya John E. Wagner Leon Boudourakis H. Bryant Nguyen Afshin Ahoubim Leslie F. Thomas Dheeraj Reddy Sirganagari

10.1053/j.ajkd.2021.11.004 article EN other-oa American Journal of Kidney Diseases 2021-12-04
Charles R. Vasquez Shruti Gupta Todd A. Miano Meaghan S. Roche Jesse Y. Hsu and 95 more Wei Yang Daniel N. Holena John P. Reilly Sarah J. Schrauben David E. Leaf M.G.S. Shashaty Carl P. Walther Samaya J. Anumudu Justin Arunthamakun Kathleen F. Kopecky Gregory P. Milligan Peter A. McCullough Thuy-Duyen Nguyen Shahzad Shaefi Megan L. Krajewski Sidharth Shankar Ameeka Pannu Juan D. Valencia Sushrut S. Waikar Zoé A. Kibbelaar Ambarish M. Athavale Peter C. Hart Shristi Upadhyay Ishaan Vohra Oyintayo Ajiboye Adam Green Jean-Sébastien Rachoin Christa Schorr Lisa Shea Daniel Edmonston Christopher L. Mosher Alexandre M. Shehata Zaza Cohen Valerie Allusson Gabriela Bambrick‐Santoyo Noor ul aain Bhatti Bijal Mehta Aquino Williams Samantha K. Brenner Patricia Walters Ronaldo C. Go Keith M. Rose Lili Chan Kusum S. Mathews Steven G. Coca Deena R. Altman Aparna Saha Howard Soh Huei Hsun Wen Sonali Bose Emily Leven Jing G. Wang Gohar Mosoyan Girish N. Nadkarni Pattharawin Pattharanitima Emily J. Gallagher Allon N. Friedman John Guirguis Rajat Kapoor Christopher Meshberger Katherine J. Kelly Chirag R. Parikh Brian T. Garibaldi Celia P. Corona‐Villalobos Yumeng Wen Steven Menez Rubab F. Malik Carmen Elena Cervantes Samir C. Gautam Mary C. Mallappallil Jie Ouyang Sabu John Ernie Yap Yohannes Adama Melaku Ibrahim Mohamed Siddhartha Bajracharya Isha Puri Mariah Thaxton Jyotsna Bhattacharya John E. Wagner Leon Boudourakis H. Bryant Nguyen Afshin Ahoubim Kianoush Kashani Shahrzad Tehranian Leslie F. Thomas Dheeraj Reddy Sirganagari Pramod Guru Yan Zhou Paul A. Bergl Jesús Rodríguez Jatan A. Shah Mrigank S. Gupta Princy Kumar Deepa G. Lazarous

10.1016/j.chest.2021.04.062 article EN CHEST Journal 2021-05-06

We present an unusual case of complement-mediated thrombotic microangiopathy (formerly known as atypical hemolytic uremic syndrome) associated with inflammatory disease in a young patient. A 26-year-old male patient no significant past medical history presented to our emergency department four-week diffuse, moderate, cramping, non-radiating abdominal pain aggravating or relieving factors. Abdominal was nausea, vomiting, and bloody stools. His physical examination revealed pale conjunctiva,...

10.7759/cureus.78447 article EN Cureus 2025-02-03

Large language models (LLMs) have achieved significant performance gains via scaling up model sizes and/or data. However, recent evidence suggests diminishing returns from such approaches, motivating the computation spent at inference time. Existing inference-time methods, usually with reward models, cast task as a search problem, which tends to be vulnerable hacking consequence of approximation errors in models. In this paper, we instead probabilistic and leverage sampling-based techniques...

10.48550/arxiv.2502.01618 preprint EN arXiv (Cornell University) 2025-02-03

The widely used Modification of Diet in Renal Disease (MDRD) formula adapts a 1.212 multiplier for individuals who are identified as African Americans (AAs) or Blacks, which leads to higher GFR estimation. As it stands, AAs have lower prevalence chronic kidney disease (CKD) but incidence end-stage renal (ESRD) compared with Whites. Many hypotheses been postulated explain this paradox, the imprecision estimation race-adaptation could be contributory. We performed single-center, longitudinal,...

10.1155/2021/1880499 article EN cc-by International Journal of Nephrology 2021-11-16
Julia L. Jezmir Maheetha Bharadwaj Alexander Chaitoff Bradford Diephuis Conor Crowley and 95 more Sandeep P. Kishore Eric Goralnick Louis T. Merriam Aimee Milliken Chanu Rhee Nicholas Sadovnikoff Sejal B. Shah Shruti Gupta David E. Leaf William B. Feldman Edy Y. Kim Carl P. Walther Samaya J. Anumudu Justin Arunthamakun Kathleen F. Kopecky Gregory P. Milligan Peter A. McCullough Thuy-Duyen Nguyen Shahzad Shaefi Megan L. Krajewski Sidharth Shankar Ameeka Pannu Juan D. Valencia Sushrut S. Waikar Zoé A. Kibbelaar Ambarish M. Athavale Peter C. Hart Shristi Upadhyay Ishaan Vohra Oyintayo Ajiboye Adam Green Jean-Sébastien Rachoin Christa Schorr Lisa Shea Daniel Edmonston Christopher L. Mosher Alexandre M. Shehata Zaza Cohen Valerie Allusson Gabriela Bambrick‐Santoyo Noor ul aain Bhatti Bijal Mehta Aquino Williams Samantha K. Brenner Patricia Walters Ronaldo C. Go Keith M. Rose Miguel A. Hernán Amy M. Zhou Ethan C. Kim Rebecca Lisk Lili Chan Kusum S. Mathews Steven G. Coca Deena R. Altman Aparna Saha Howard Soh Huei Hsun Wen Sonali Bose Emily Leven Jing G. Wang Gohar Mosoyan Girish N. Nadkarni Pattharawin Pattharanitima Allon N. Friedman John Guirguis Rajat Kapoor Christopher Meshberger Katherine Kelly Chirag R. Parikh Brian T. Garibaldi Celia P. Corona‐Villalobos Yumeng Wen Steven Menez Rubab F. Malik Elena Cervantes Samir C. Gautam Mary C. Mallappallil Jie Ouyang Sabu John Ernie Yap Yohannes Adama Melaku Ibrahim Mohamed Siddartha Bajracharya Isha Puri Mariah Thaxton Jyotsna Bhattacharya John E. Wagner Leon Boudourakis H. Bryant Nguyen Afshin Ahoubim Leslie F. Thomas Dheeraj Reddy Sirganagari Pramod Guru Kianoush Kashani

Many US states published crisis standards of care (CSC) guidelines for allocating scarce critical resources during the COVID-19 pandemic. However, performance these in maximizing their population benefit has not been well tested. In 2,272 adults with requiring mechanical ventilation drawn from Study Treatment and Outcomes Critically Ill Patients (STOP-COVID) multicenter cohort, we test following three approaches to CSC algorithms: Sequential Organ Failure Assessment (SOFA) scores grouped...

10.1016/j.xcrm.2021.100376 article EN cc-by-nc-nd Cell Reports Medicine 2021-07-28

Abstract Accurate assessment of blood volume ( BV ) may be helpful for prescribing hemodialysis HD and reducing complications related to hypovolemia overload. Monitoring changes in relative RBV using hematocrit, e.g., Crit‐Line Monitor CLM‐III ), an indirect method, cannot used determine absolute . We report the first study measurement assessing status patients indicator dilutional method. Ten adult were enrolled this prospective observational study. was performed before after analysis BVA...

10.1111/hdi.12105 article EN Hemodialysis International 2013-11-22
Adam Keene Andrew J. Admon Samantha K. Brenner Shruti Gupta Deepa G. Lazarous and 95 more David E. Leaf Hayley B. Gershengorn Carl P. Walther Samaya J. Anumudu Justin Arunthamakun Kathleen F. Kopecky Gregory P. Milligan Peter A. McCullough Thuy-Duyen Nguyen Shahzad Shaefi Brian O’Gara Megan L. Krajewski Sean M Baskin Sidharth Shankar Juan D. Valencia Ameeka Pannu Margaret M. Hayes E. Wilson Grandin Sushrut S. Waikar Zoé A. Kibbelaar Ambarish M. Athavale Peter C. Hart Shristi Upadhyay Ishaan Vohra Oyintayo Ajiboye Adam Green Jean-Sébastien Rachoin Christa Schorr Lisa Shea Daniel Edmonston Christopher L. Mosher Alexandre M. Shehata Zaza Cohen Valerie Allusson Gabriela Bambrick‐Santoyo Noor ul aain Bhatti Bijal Mehta Aquino Williams Samantha K. Brenner Patricia Walters Ronaldo C. Go Keith M. Rose Miguel A. Hernán Rebecca Lisk Lili Chan Kusum S. Mathews Steven G. Coca Deena R. Altman Aparna Saha Howard Soh Huei Hsun Wen Sonali Bose Emily Leven Jing G. Wang Gohar Mosoyan Girish N. Nadkarni Pattharawin Pattharanitima Emily J. Gallagher Allon N. Friedman John Guirguis Rajat Kapoor Christopher Meshberger Katherine Kelly Chirag R. Parikh Brian T. Garibaldi Celia P. Corona‐Villalobos Yumeng Wen Steven Menez Rubab F. Malik Carmen Elena Cervantes Samir C. Gautam Mary C. Mallappallil Jie Ouyang Sabu John Ernie Yap Yohannes Adama Melaku Ibrahim Mohamed Siddhartha Bajracharya Isha Puri Mariah Thaxton Jyotsna Bhattacharya John E. Wagner Leon Boudourakis H. Bryant Nguyen Afshin Ahoubim Leslie F. Thomas Dheeraj Reddy Sirganagari Pramod Guru Kianoush Kashani Shahrzad Tehranian Yan Zhou Paul A. Bergl Jesús Rodríguez Jatan A. Shah Mrigank S. Gupta

Objective To determine whether surge conditions were associated with increased mortality. Design Multicenter cohort study. Setting U.S. ICUs participating in STOP-COVID. Patients Consecutive adults COVID-19 admitted to between March 4 and July 1, 2020. Interventions None Measurements Main Results The main outcome was 28-day in-hospital assess the association admission an ICU during a period mortality, we used two different strategies: (1) inverse probability weighted...

10.1177/08850666211067509 article EN Journal of Intensive Care Medicine 2021-12-23

Objective. To assess the demographic characteristics, risk factors and perinatal outcomes among maternal intensive care unit (ICU) admissions in New Jersey from 1997 to 2005.Methods. Data were obtained a linked database MCH epidemiology programme Jersey. Chi-square test was used for bivariate analysis stepwise logistic regression influence of potential pregnancy complications.Results. There 15 447 (1.54%) ICU 23 deaths (0.15%) 1 004 116 pregnancies. Analysis revealed that age, race smoking...

10.1080/14767050902874097 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2009-06-03

Ionized hypocalcemia is common in critically ill patients with COVID-19 and associated adverse outcomes. We previously developed a linear model that estimates ionized calcium (ICa) by adjusting total (TCa) for the three components of anion gap albumin. On internal validation, it outperformed popular method corrects TCa albumin alone (cTCa) diagnosing low ICa. In this study, we sought to externally validate our ICa hospitalized positive patients.We retrospectively studied all 200 who were...

10.1177/00045632211049983 article EN other-oa Annals of Clinical Biochemistry International Journal of Laboratory Medicine 2021-10-24

Ogilvie's syndrome, also known as acute colonic pseudo-obstruction (ACPO), is a rare, nonobstructive dilation of the colon unclear etiology. We present case patient who presented with syndrome and significant hypokalemia due to loss despite repletion. This report demonstrates difficulty in diagnosis, treatment, outcome.

10.1155/2022/6431248 article EN cc-by Case Reports in Nephrology 2022-11-23

Jatoi, Tahir A.; Sasidharan, Sandeep R.; Elhawary, Omar N.; Abushawer, Mohammad W.; Agarwal, Sonalika; Mallappallil, Mary C.; Puri, Isha Author Information

10.1681/asn.20233411s1402c article EN Journal of the American Society of Nephrology 2023-11-01

Octreotide, a synthetic analog of somatostatin, is widely utilized for its inhibitory effects on various hormones, including growth hormone, insulin, and glucagon. Its applications span conditions such as acromegaly, carcinoid tumors, gastrointestinal bleeding due to ability reduce portal venous pressure. Additionally, it serves crucial role in nuclear medicine imaging the management hepatorenal syndrome. We report case 44-year-old man with type 2 diabetes mellitus (T2DM) stage 5 chronic...

10.7759/cureus.68246 article EN Cureus 2024-08-30
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