Rajat Kapoor
A5013046793- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Bone fractures and treatments
- COVID-19 and healthcare impacts
- Orthopedic Surgery and Rehabilitation
- Total Knee Arthroplasty Outcomes
- Respiratory Support and Mechanisms
- Shoulder Injury and Treatment
- Sepsis Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Knee injuries and reconstruction techniques
- Tendon Structure and Treatment
- Intensive Care Unit Cognitive Disorders
- Elbow and Forearm Trauma Treatment
- Cerebral Venous Sinus Thrombosis
- Foot and Ankle Surgery
- Thermal Regulation in Medicine
- Intraocular Surgery and Lenses
- Hip and Femur Fractures
- Reconstructive Surgery and Microvascular Techniques
- Bone Tumor Diagnosis and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Ophthalmology and Eye Disorders
- Bone and Joint Diseases
- Hospital Admissions and Outcomes
Sarojini Naidu Medical College
2018-2025
Indiana University – Purdue University Indianapolis
2013-2024
Indiana University Health
2013-2024
Creative Commons
2021-2023
Association Clinique et Thérapeutique Infantile du Val de Marne
2023
Christie's
2023
Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences
2023
Indiana University School of Medicine
2020-2022
St George's Hospital
2022
St George’s University Hospitals NHS Foundation Trust
2022
<h3>Importance</h3> The US is currently an epicenter of the coronavirus disease 2019 (COVID-19) pandemic, yet few national data are available on patient characteristics, treatment, and outcomes critical illness from COVID-19. <h3>Objectives</h3> To assess factors associated with death to examine interhospital variation in treatment for patients <h3>Design, Setting, Participants</h3> This multicenter cohort study assessed 2215 adults laboratory-confirmed COVID-19 who were admitted intensive...
Therapies that improve survival in critically ill patients with coronavirus disease 2019 (COVID-19) are needed. Tocilizumab, a monoclonal antibody against the interleukin 6 receptor, may counteract inflammatory cytokine release syndrome severe COVID-19 illness.
The aim of this study was to determine the frequency venous thromboembolism in critically ill coronavirus disease 2019 patients and associate a degree inflammatory marker elevation development.An observational that identified with severe between March 12, 2020, 31, 2020. Data reported are those available through May 6, 2020.A multicenter including three Indianapolis area academic hospitals.Two-hundred forty consecutive confirmed acute respiratory syndrome 2 infection were admitted one...
Hypercoagulability may be a key mechanism of death in patients with coronavirus disease 2019 (COVID-19).
One of the defining features novel coronavirus disease 2019 infection has been high rates venous thromboses. The present study aimed to describe prevalence thromboembolism in critically ill patients receiving different regimens prophylactic anticoagulation.Single-center retrospective review using data from with confirmed severe acute respiratory syndrome 2 requiring intubation.Tertiary-care center Indianapolis, IN, United States.Patients hospitalized at international units Health Methodist...
Rationale: Variation in hospital mortality has been described for coronavirus disease (COVID-19), but the factors that explain these differences remain unclear. Objective: Our objective was to use a large, nationally representative data set of critically ill adults with COVID-19 determine which variability. Methods: In this multicenter cohort study, we examined hospitalized ICUs at 70 U.S. hospitals between March and June 2020. The primary outcome 28-day mortality. We patient-level...
COVID-19 detection currently relies on testing by reverse transcription polymerase chain reaction (RT-PCR) or antigen testing. However, SARS-CoV-2 is expected to cause significant metabolic changes in infected subjects due both requirements for rapid viral replication and host immune responses. Analysis of volatile organic compounds (VOCs) from human breath can detect these therefore an alternative RT-PCR assays. To identify VOC biomarkers COVID-19, exhaled samples were collected two sample...
Posterior cruciate ligament (PCL) avulsion fractures of the tibia with ipsilateral tibial shaft represent a rare but challenging orthopedic injury, necessitating careful consideration surgical interventions for optimal outcomes. This case report presents successful management fracture (proximal 1/3rd junction) along PCL using novel approach open reduction internal fixation (ORIF) Locking compression plate (LCP) cannulated cancellous screw and spiked washer avulsion. There are no reports or...
Abstract Introduction: Distal tibial fractures account for approximately 7% of all and can present a management challenge because their inherent instability, scarcity soft tissues, subcutaneous nature, poor vascularity bone. Despite the availability various modern techniques, there is either no or insufficient evidence to draw definitive conclusions on best surgical intervention. The study compares functional radiological outcomes intramedullary nailing (IMN) with distal tibia-locking...
Beta cell dysfunction is suggested in patients with COVID-19 infections. Poor glycemic control ICU associated poor patient outcomes. This a single center, retrospective analysis of 562 an intensive care unit from 1 March to 30 April 2020. We review the time range (70-150 mg/dL) spent by critically ill and non-COVID-19 patients, along daily insulin use. Ninety-three cohort 469 were compared for percentage blood glucose TIR average The significantly less (44.4% vs. 68.5%). Daily use was higher...
This study aimed to determine whether obesity is independently associated with major adverse clinical outcomes and inflammatory thrombotic markers in critically ill patients COVID-19.The primary outcome was in-hospital mortality adults COVID-19 admitted intensive care units across the US. Secondary were acute respiratory distress syndrome (ARDS), kidney injury requiring renal replacement therapy (AKI-RRT), events, seven blood of inflammation thrombosis. Unadjusted multivariable-adjusted...
Objectives: Differences in mortality rates previously reported critically ill patients with coronavirus disease 2019 have increased the need for additional data on and risk factors death. We conducted this study to describe length of stay, mortality, associated in-hospital mechanically ventilated 2019. Design: Observational study. Setting: Two urban, academic referral hospitals Indianapolis, Indiana. Patients or Subjects: Participants were 18 years old older, admitted between March 1, 2020,...
Many US states published crisis standards of care (CSC) guidelines for allocating scarce critical resources during the COVID-19 pandemic. However, performance these in maximizing their population benefit has not been well tested. In 2,272 adults with requiring mechanical ventilation drawn from Study Treatment and Outcomes Critically Ill Patients (STOP-COVID) multicenter cohort, we test following three approaches to CSC algorithms: Sequential Organ Failure Assessment (SOFA) scores grouped...
Objective To determine whether surge conditions were associated with increased mortality. Design Multicenter cohort study. Setting U.S. ICUs participating in STOP-COVID. Patients Consecutive adults COVID-19 admitted to between March 4 and July 1, 2020. Interventions None Measurements Main Results The main outcome was 28-day in-hospital assess the association admission an ICU during a period mortality, we used two different strategies: (1) inverse probability weighted...