A5003031121- Carcinogens and Genotoxicity Assessment
- Effects and risks of endocrine disrupting chemicals
- Air Quality and Health Impacts
- Occupational exposure and asthma
- Toxic Organic Pollutants Impact
- Heavy Metal Exposure and Toxicity
- CAR-T cell therapy research
- Sulfur Compounds in Biology
- Pesticide Exposure and Toxicity
- Glioma Diagnosis and Treatment
- Immune Cell Function and Interaction
- Indoor Air Quality and Microbial Exposure
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cancer Immunotherapy and Biomarkers
- Neonatal Health and Biochemistry
- Skin Protection and Aging
- Occupational Health and Safety Research
- Metabolism and Genetic Disorders
- Trace Elements in Health
- Animal testing and alternatives
- Occupational and environmental lung diseases
- Analytical Chemistry and Chromatography
- Cancer, Hypoxia, and Metabolism
- Barrier Structure and Function Studies
- Heavy metals in environment
University Hospital of Zurich
2022-2025
University of Zurich
2022-2024
Institute for Prevention and Occupational Medicine
2015-2024
University Hospital of Geneva
2024
Physiotherapie und Lauftherapie Zentrum
2020-2021
Salzburg University of Applied Sciences
2017
University of Alberta
2016
Ruhr University Bochum
2006-2015
Binghamton University
2015
Leipzig University
2015
This investigation aims to explore determinants of exposure particle size-specific welding fume. Area sampling ultrafine particles (UFP) was performed at 33 worksites in parallel with the collection respirable particles. Personal and inhalable carried out breathing zone 241 welders. Median mass concentrations were 2.48 mg m(-3) for 1.29 when excluding 26 users powered air-purifying respirators (PAPRs). Mass highest flux-cored arc (FCAW) gas applied (median particles: 11.6 m(-3))....
Inhalation of high concentrations zinc oxide particles (ZnO) may cause metal fume fever. In an earlier human inhalation study, no effects were observed after exposure to ZnO 0.5 mg/m3. Further data from experimental studies with pure in the concentration range between and 2.5 mg/m3 are not available. It was aim this study establish concentration-response relationship nano-sized particles.Sixteen healthy subjects exposed filtered air (0.5, 1.0 2.0 mg/m3) for 4 h on different days, including 2...
Industrial use of aniline is increasing worldwide with production estimated to surpass 5.6 million metric tons in 2016. Exposure occurs via air, diet, and water augmenting the risk exposing a large number individuals. Early observations suggest that metabolized paracetamol/acetaminophen, likely explaining omnipresence low concentrations paracetamol European populations. This concern as recent studies implicate disrupter reproduction. Here, we show through steroidogenic profiling exposure led...
Abstract Homosalate (HMS) is a UV filter used in sunscreens and personal care products as mixture of cis - trans -isomers. Systemic absorption after sunscreen use has been demonstrated humans, concerns have raised about possible endocrine activity HMS, making general population exposure assessment desirable. In previous study, it was shown that the oral bioavailability -HMS ( c HMS) lower than t by factor 10, calling for separate evaluation both isomers risk assessment. The aim current study...
Background: Several aromatic amines (AA) could cause bladder cancer and are an occupational hygiene problem in the workplace. However, little is known about percutaneous absorption of chemicals via impaired skin efficacy protection measures to reduce internal exposure. Aims: To determine impact status on exposure AA workers manufacturing rubber products. Methods: 51 occupationally exposed aniline o-toluidine were examined. The workplace conditions, risk factors for use personal protective...
Firefighters are exposed to a variety of hazardous substances including carcinogens such as polycyclic aromatic hydrocarbons (PAH) during firefighting. In order minimize the uptake into body, firefighters wear personal protective equipment. Only few data exist from real-life firefighting missions and under common although highly variable exposure scenarios fighting fires in residential buildings, outdoor, vehicle fires. The aim this study is assess levels 1-Hydroxypyrene (1-OHP) marker for...
Prostate cancer is the second deadliest tumor in men globally, despite advent of novel drugs. Therapeutic modalities targeting Specific Membrane Antigen (PSMA) have provided benefit to patients but suffer from on-target off-tumor liabilities responsible for side effects observed clinical practice. These are a result expression PSMA healthy tissues, such as salivary glands, lacrimal intestine, and kidneys. Innovative ligands against better prostate targets therefore needed. Here, we present...