A5016491498- Systemic Lupus Erythematosus Research
- T-cell and B-cell Immunology
- Dermatology and Skin Diseases
- Immunotherapy and Immune Responses
- Nail Diseases and Treatments
- Psoriasis: Treatment and Pathogenesis
- Diabetes and associated disorders
- Acne and Rosacea Treatments and Effects
- Renal Diseases and Glomerulopathies
- Herpesvirus Infections and Treatments
- Complement system in diseases
- Immune Cell Function and Interaction
- Galectins and Cancer Biology
- Atherosclerosis and Cardiovascular Diseases
Anhui Medical University
2009-2022
Tianjin Economic-Technological Development Area
2022
Second Hospital of Anhui Medical University
2015-2022
Ministry of Education of the People's Republic of China
2013
Genome-wide association studies (GWASs) have revealed a large number of genetic risk loci for many autoimmune diseases. One clear finding emerging from the published autoimmunity is that different diseases, such as psoriasis and systemic lupus erythematosus (SLE), share susceptibility loci. Our study explores additional shared by SLE in Chinese Han population.In total, 20 single nucleotide polymorphisms (SNPs) 17 previously reported 34 SNPs 24 were investigated our initial GWAS dataset....
Systemic lupus erythematosus (SLE) is a prototypic systemic autoimmune disease. Complement component 4 (C4) has be proved to play role in pathogenesis of SLE. In the present study, we investigated effect C4 on T cells differentiation.Thirty SLE patients were included this study. CD4+ isolated from healthy subjects, and dendritic (DCs) subjects or patients. was supplemented co-incubate with DCs.Serum concentration positively correlated regulatory cell (Treg) percentage (R(2) = 0.5907, p <...
To understand the distribution characteristics of onset time, age and gender pityriasis alba (PA) patients in dermatology clinic our hospital to further explore pathogenesis disease provide a scientific basis for prevention treatment this disease.The clinical data 2726 outpatients with PA diagnosed first time from January 2016 December 2020 were collected descriptively analyzed.The number was less March. The peak reached July August. cases affected by COVID-19 epidemic significantly lower...