A5102735403- COVID-19 Clinical Research Studies
- COVID-19 diagnosis using AI
- Long-Term Effects of COVID-19
- Voice and Speech Disorders
- Antibiotic Resistance in Bacteria
- Inflammatory Bowel Disease
- Traditional Chinese Medicine Analysis
- Viral gastroenteritis research and epidemiology
- Pharmacological Effects of Natural Compounds
- Speech Recognition and Synthesis
- Tracheal and airway disorders
- Cerebral Venous Sinus Thrombosis
- Plant-based Medicinal Research
- Advanced Glycation End Products research
- Traditional Chinese Medicine Studies
- interferon and immune responses
- Immune Response and Inflammation
- Circular RNAs in diseases
- Cleft Lip and Palate Research
- Respiratory Support and Mechanisms
- Antibiotic Use and Resistance
- Acute Ischemic Stroke Management
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer-related molecular mechanisms research
- Adversarial Robustness in Machine Learning
Fujian University of Traditional Chinese Medicine
2015-2024
Swinburne University of Technology
2023
Data61
2023
Commonwealth Scientific and Industrial Research Organisation
2023
National Institute of Diabetes and Digestive and Kidney Diseases
2022
ProQuest (United States)
2022
Chinese PLA General Hospital
2022
Chinese People's Liberation Army
2022
Hubei University of Arts and Science
2020-2021
Xiangyang Central Hospital
2020-2021
Abstract The aim of this study was to analyze initial chest computed tomography (CT) findings in COVID-19 pneumonia and identify features associated with poor prognosis. Patients RT-PCR-confirmed infection were assigned recovery group if they made a full death died within 2 months hospitalization. Chest CT examinations for ground-glass opacity, crazy-paving pattern, consolidation, fibrosis scored by two reviewers. total score comprised the sum lung involvement (5 lobes, scores 1–5 each lobe,...
Gualou Guizhi decoction (GLGZD) is an ancient Chinese classical prescription widely used to treat ischemic stroke. However, the molecular mechanisms of GLGZD promoting angiogenesis are unavailable.This study investigates effect as well its mechanism.Ischemic stroke was established by middle cerebral artery occlusion/reperfusion (MCAO/R) in male Sprague-Dawley (SD) rats. The groups received (3.6, 7.2 and 14.4 g/kg) orally. Oxygen-glucose deprivation/reoxygenation (OGD/R) model constructed...
Background Leukokeratosis of the vocal cords is a clinical descriptive diagnosis, which includes group squamous intraepithelial lesions cord mucosa. We investigated classification and treatment efficacy leukokeratosis cords. Methods conducted retrospective analysis medical history, laryngoscopic examinations, morphological features under surgical microscope, pathology results 360 cases to examine correlations among modalities, therapeutic effects, features. Results All were divided into four...
COVID-19 is an emerging disease with transmissibility and severity. So far, there are no effective therapeutic drugs or vaccines for COVID-19. The most serious complication of a type pneumonia called 2019 novel coronavirus-infected (NCIP) about 4.3% mortality rate. Comparing to chest Digital Radiography (DR), it recently reported that Computed Tomography (CT) more useful serve as the early screening diagnosis tool NCIP. In this study, aimed help physicians make diagnostic decision, we...
Ulcerative colitis (UC) is a common inflammatory intestinal disease. Astragali Radix (AR) one of the traditional Chinese medicines used in clinic for UC treatment. In our previous study, whole ingredient extract (WIE) from AR have been proved to possess better immunomodulatory effects on immunosuppressed mice compared with conventional water extraction (WAE). present we further evaluated therapeutic WIE against dextran sodium sulfate (DSS)-induced through systemic immune regulation.Gradient...
Wilsonian crisis (hemolytic and acute liver failure [ALF] in Wilson’s disease) is fatal almost all patients ultimately need a timely transplantation to save their lives. How safely pass the critical period still big challenge doctors especially pediatricians facing more difficult situations blood purification. Here, we report about 7-year-old child (weight 21 kg) presenting with severe hemolysis impending ALF that made rapid recovery prompt initiation of plasmapheresis combined continuous...
Objectives The changes in metabolism by human adenovirus (HAdV) infection was unclear. potential mechanism of HAdV-7 causing acute respiratory tract explored. Methods Totally 35 patients with infection, 32 asymptomatic cases and 14 healthy controls were enrolled from an outbreak the army. serum samples analyzed untargeted targeted metabolomics. effects differential metabolites verified on replication A549 cell line. Results metabolomics analysis revealed more significant classes...
Gualou Guizhi granules (GLGZGs) are a classical formula of traditional Chinese medicine, which have been commonly used to treat dysfunction after stroke, epilepsy and spinal cord injury.
Abstract Purpose : The aim of this study was to retrospectively analyze chest Computed Tomography (CT) findings in COVID-19 pneumonia and identify features associated with poor prognosis. Methods This retrospective review included 46 patients RT-PCR confirmed infection. Basic clinical characteristics detailed CT were evaluated compared between who recovered (n = 40) from coronavirus those expired 6). Chest examinations for ground-glass opacity, crazy-paving pattern, consolidation, fibrosis...
Intravenous thrombolysis is the primary therapy for acute ischemic stroke (AIS), but it has some complications, including symptomatic intracranial hemorrhage, orolingual angioedema, and extracranial bleeding. However, thyroid disorders associated with are very rare.A 56-year-old man developed pain neck swelling after recombinant tissue plasminogen activator.Ultrasound revealed a diffusely enlarged linear hypoechoic areas throughout entire gland, resembling "cracked" appearance.The patient...
Human adenovirus (HAdV) infection causes excessive inflammation associated with severe tissue injury, such as pneumonia. The molecules involved in the underlying inflammatory mechanisms remain to be elucidated. Receptor for advanced glycation end product (RAGE) is mainly expressed on immune cells and lung tissues, it a key factor initiation development of inflammation. RAGE can cleaved by metalloprotease 9 (MMP9) release extracellular segment, which named soluble (sRAGE), into intercellular...
Recruit training sites are places with a high incidence of respiratory infectious diseases. Effective surveillance for acute diseases in recruit site is an important way to prevent disease outbreaks.Eight hundred recruits (722 males and 78 females) enlisted autumn 2015 received background survey within 24 h settlement at the site, including their general personal information, vaccination history, mental status clinical symptoms. Then, nasopharyngeal swabs these were collected detect common...
Elucidating the quality markers(Q-markers) of traditional Chinese medicines is essential for understanding mechanisms action and promoting rational use as well developing medicine-derived drugs. Studies have shown that surface plasmon resonance(SPR) promising in this field. This study proposed a method based on pull-down with SPR chips to predict Q-markers Angong Niuhuang pills(AGNHP). Firstly, 71 main chemical components AGNHP were analyzed by UPLC-Q-TOF-MS, then network pharmacology was...
This paper reports a complete case of severe acute respiratory distress syndrome (ARDS) caused by coronavirus disease 2019 (COVID-19), who presented with rapid deterioration oxygenation during hospitalization despite escalating high-flow nasal cannulation to invasive mechanical ventilation. After inefficacy lung-protective ventilation, positive end-expiratory pressure (PEEP) titration, prone position, we administered extracorporeal membrane (ECMO) as salvage support ultra-protective...
Background: Early detection and treatment under endoscopy have effectively decreased the mortality of colorectal cancer (CRC). But it is difficult to detect early CRC white light (WLE). Artificial intelligence (A.I.) assisted diagnose system are accumulated, but assisting diagnosis lack due clinical design sample size limitation. We propose establish a propagable AI-assisted characterization (ECRC-CAD).Methods: Establishing algorithms were implemented in four (i.e., municipal, provincial,...
Abstract Background Ulcerative colitis (UC) is a common inflammatory intestinal disease. Astragali Radix (AR) one of the traditional Chinese medicines used in clinic for UC treatment. In our previous study, whole ingredient extract (WIE) from AR have been proved to possess better immunomodulatory effects on immunosuppressed mice compared with water extraction (WAE). At present we further evaluated systemic immune regulation and therapeutic WIE WAE dextran sodium sulfate (DSS)-induced mice....