A5089655230- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Urological Disorders and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Pectus Deformity Diagnosis and Treatment
- Organ Donation and Transplantation
- Congenital Diaphragmatic Hernia Studies
- Intestinal Malrotation and Obstruction Disorders
- Gastrointestinal disorders and treatments
- Urologic and reproductive health conditions
- Gallbladder and Bile Duct Disorders
- Sarcoidosis and Beryllium Toxicity Research
- Pediatric Urology and Nephrology Studies
- Reconstructive Surgery and Microvascular Techniques
- Esophageal and GI Pathology
- Congenital Anomalies and Fetal Surgery
- Ureteral procedures and complications
- Congenital limb and hand anomalies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Infectious Diseases and Tuberculosis
- Genital Health and Disease
- Eosinophilic Esophagitis
- Abdominal Trauma and Injuries
- Pleural and Pulmonary Diseases
- Pediatric Pain Management Techniques
Hôpital Femme Mère Enfant
2010-2024
Hospices Civils de Lyon
2012-2024
Institut de Transplantation Urologie en Nephrologie
2024
Groupe Hospitalier de l'Institut Catholique de Lille
2023
Université Claude Bernard Lyon 1
2008-2022
Centre Hospitalier Universitaire de Rouen
2020
Université de Rouen Normandie
2020
Lille’s Cardiology Hospital
2020
Lyon College
2019
Centre de Recherche Cardio-Thoracique de Bordeaux
2017
Partial liver grafts from ex situ splitting are considered marginal due to prolonged static cold storage. The use of hypothermic oxygenated perfusion (HOPE) may offer a strategy improve preservation split grafts. In this single-center pilot study, we prospectively performed during HOPE (HOPE-Split) for adult and pediatric partial over 1-year period (November 1, 2020 December 2021). primary safety endpoint was based on the number graft-related adverse events (LGRAEs) per recipient, including...
Optimizing graft preservation is key for ex-situ split grafts in pediatric liver transplantation (PSLT). Hypothermic Oxygenated Perfusion (HOPE) improves ischemia-reperfusion injury (IRI) and post-operative outcomes adult LT. This study compares the use of HOPE partial to static cold storage (SCS-Split) gold standard living donor (LDLT). All consecutive HOPE-Split, SCS-Split LDLT performed between 2018–2023 recipients were included. Post‐reperfusion syndrome (PRS, drop ≥30% systolic arterial...
Per-oral endoscopic myotomy (POEM) is a recommended treatment modality for achalasia, but there little published data its use in children. The objective of the present study was to evaluate whether POEM clinically effective and safe children.International multicenter retrospective conducted 14 tertiary centers that included consecutive children who underwent between January 2012 August 2018. Outcomes, such as clinical response were assessed whenever available. Adverse events factors...
Split liver transplantation (LT) has been developed to increase organ availability, but it results in prolonged cold ischemia and higher risks of postreperfusion bleeding ischemia-reperfusion injury (IRI). Therefore, partial grafts are considered as marginal grafts. Dynamic preservation strategies have proposed minimize IRI optimize post-LT outcomes, especially for extended criteria donor livers; however, all current trials assessing machine perfusion exclude grafts.1 For instance, our team...
Ex-premature infants, before 45 weeks postconceptional age, are at high-risk of apnoea after surgery. General anaesthesia increases the risk apnoea. We evaluated tolerance and efficiency caudal performed in 25 consecutive conscious ex-premature infants for inguinal herniotomies. N2O/O2 EMLA cream used to facilitate puncture. Anaesthesia procedure, patient comfort complications following 24 postoperative hours were studied. report good conditions without compromising baby's few perioperative...
The aim of this work is to report our early experiences about the benefits liver transplantation (LT) in treatment persistent neurological symptoms Wilson's disease (WD) patients.We describe findings 4 WD patients with impairment or treated by LT: 2 had transplants due worsening despite long-term appropriate medical treatment. other required LT because associated failure. Patients were evaluated using modified Rankin scale and Unified Disease Rating Scale (UWDRS).The experienced improvement...
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), is a highly aggressive neoplasm that typically occurs in young females. Paraneoplastic hypercalcemia associated two thirds cases. Recent studies demonstrated this rare tumor harbors same molecular features malignant rhabdoid secondary to SMARCA4/BRG1 mutations. We illustrate herein typical bilateral case SCCOHT with comprehensive characterization 14-year-old girl. also discuss value SMARCA4 immunostaining diagnostic approach...
We evaluated the use of high frequency oscillatory ventilation (HFOV) during congenital diaphragmatic hernia repair. After preoperative stabilization, 22 newborn infants were ventilated with HFOV surgery. Ventilatory settings, blood gas values and oxygenation index recorded before, after surgical No differences noted for these variables. complications related to recorded. According surgeon, repair is facilitated. This study confirms that CDH can be safely repaired using anaesthesia.
Ex vivo split liver transplantation in pediatric recipients has shown inferior results compared with whole grafts. One factor among others contributing to grafts being considered as marginal is the prolonged static cold storage time related ex splitting. End ischemic hypothermic oxygenated perfusion a validated strategy improve outcomes of and may thus also benefit grafts.We present first case full left/full right procedure performed during perfusion.We standardized surgical two-step...
We report a case of desmoplastic small round cell tumor (DSRCT) arising in the kidney 14-year-old female. The subject presented with gross hematuria. Medical imaging uncovered left renal mass without regional or metastatic extension. showed morphological, immunohistochemical, and molecular features DSRCT. Immunostaining revealed polyphenotypic differentiation. Molecular analysis detected fusion transcript resulting from t(11;22)(p13;q12) reciprocal translocation, which characterized this...
Abstract Pitt–Hopkins syndrome (PTHS) is characterized by distinctive facial dysmorphism, profound intellectual disability, and the possible occurrence of epilepsy breathing anomalies. It caused haploinsufficiency TCF4 gene. No significant difference in clinical severity has been reported to date between PTHS patients carrying 18q21 deletions including gene, those harboring point mutations, suggesting a lack genotype/phenotype correlation. Moreover, size gene does not appear have effect on...