A5031787463- Sleep and Wakefulness Research
- Parkinson's Disease Mechanisms and Treatments
- Restless Legs Syndrome Research
- Sleep and related disorders
- Trace Elements in Health
- Diabetes Management and Research
- Health disparities and outcomes
- Heart Rate Variability and Autonomic Control
- Heavy Metal Exposure and Toxicity
- Neurological disorders and treatments
- Prion Diseases and Protein Misfolding
- Genetic Neurodegenerative Diseases
- Neurological Disorders and Treatments
- Dysphagia Assessment and Management
- Historical Astronomy and Related Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Cholinesterase and Neurodegenerative Diseases
- Health, psychology, and well-being
- Memory and Neural Mechanisms
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Ancient Egypt and Archaeology
- Health and Wellbeing Research
- Botulinum Toxin and Related Neurological Disorders
- Electrolyte and hormonal disorders
- Sleep and Work-Related Fatigue
Universidade de São Paulo
2014-2018
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2015-2017
In-Q-Tel
2016
Swiss Insurance Association
2012
Medical University of Vienna
1993-2005
Vienna General Hospital
2002-2005
University of Vienna
1996-2005
Graz University Hospital
2002
To compare the self-reported estimation of sleep quality evaluated by Pittsburgh Sleep Quality Index (PSQI) and life assessed Life (QLI).The PSQI comprised 19 questions a wide variety factors relating to quality. The QLI consisted 10 items for self assessment different dimensions quality.A representative Austrian sample (n = 1049) aged above 15 years.Interviews in homes participants.32.1% could be classified as poor sleepers (37% females, 26.5% males). decreased with increasing age,...
Atypical parkinsonian syndromes (APS) such as multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration are characterized by poor response to antiparkinsonian medication rapid clinical deterioration. We used SPECT [123I]beta-CIT a label of dopamine transporters study the progression presynaptic dopaminergic in Parkinson's disease (PD) APS. Twenty-four PD patients with short duration (2.4 +/- 1.5 years), 12 long (9.2 2.6 10 APS (disease 2.1 nine essential tremor...
A group of young patients with insulin-dependent diabetes mellitus (n = 14; 8 men, 6 women; 33.1 ± 8.9 years) were examined by topographic EEG mapping under normoglycemic and hypoglycemic conditions (glucose levels after intravenous insulin injection down to 32.6 7.6 mg/dl). From the clinical aspect, 7 them had a good poor awareness hypoglycemia. During hypoglycemia, decrease in alpha activity (p < 0.05), an increase delta especially theta 0.05) found. The most sensitive parameter was...
A double-blind, placebo-controlled, parallel-group, multicentre study was conducted to evaluate the efficacy of pentoxifylline (Trental) in patients with multi-infarct dementia (MID) according DSM-III-R criteria. Men and women aged 45 years or older, a Hachinski Ischemia Scale score > = 7 Mini Mental State Examination (MMSE) 10-25 at entry, computed tomographic evidence vascular disease were enrolled. total 289 randomised receive either oral 400 mg t.i.d. placebo for 9 months, assessed every...
Dopaminergic treatment is very effective in restless legs syndrome (RLS) and periodic leg movements sleep (PLMS). However, neuroreceptor imaging studies that addressed altered striatal dopaminergic function have given controversial results. In this present study, 14 patients with idiopathic RLS (iRLS) PLMS a good response to non-dopaminergic ten healthy sex- age-matched controls were investigated off-medication by using 123I-IBZM SPECT. symptoms disturbances evaluated three nights of...
To describe characteristics of REM sleep behavior disorder in Wilson's disease.Questionnaire-based interviews (patients and relatives), neurological examinations, two-week prospective dream-diary, video-polysomnography, transcranial sonography, MRI.Four disease cases with were described; three had as initial symptom. All showed mesencephalic tegmental/tectal sonographic hyperechogenicities two presented ponto-mesencephalic tegmental MRI hyperintensities.This first description literature...
The few reports available on olanzapine in Huntington's disease (HD) are insufficiently documented and/or dosed. We describe a 30-year-old woman with genetically confirmed HD who presented severe chorea. She was not able to eat or dress without help and did respond haloperidol; the motor scale of Unified Rating Scale (UHDRS-I) revealed 65 possible 124 points. After admission, we treated patient high dose (30 mg daily). chorea almost ceased next 2 days, she walk assistance (UHDRS-I 21...
<b>Background:</b> Dopaminergic and opioidergic drugs have been found to be effective in patients with restless legs syndrome (RLS). <b>Objectives:</b> To test the effect of apomorphine—a combined dopaminergic agonist—and subsequent selective antagonism by naloxone metoclopramide on subjective objective symptoms idiopathic RLS. <b>Methods:</b> Nine RLS were pretreated oral domperidone for three days. A modified suggested immobilisation (SIT) was carried out between 8 pm 1 am under following...
The purpose of this study was to determine subjective health-related quality life (HRQoL) in a sample the Austrian population over 14 years age order evaluate effect socio-demographic variables on HRQoL.HRQoL determined by means index-German version (QLI-Ge). influence HRQoL assessed statistical analysis using Kruskal-Wallis test and an variance.A random-quota procedure used get balanced representation from regions demographic groups population. consisted 1049 participants, 493 men 556...
To determine characteristics, clinical significance, frequency, and mimics of restless legs syndrome (RLS) in a cohort Wilson's disease (WD, n = 42/f 18), compared to healthy, matched controls.Structured interviews (patients caregiving family members), repeated neurological examinations (afternoon presleep), comprehensive laboratory tests, WD-, RLS-, sleep-specific rating scales, video-polysomnography.Thirteen patients with WD (13/42 31.0%) clearly fulfilled the five diagnostic criteria RLS;...
The precise etiology of the restless legs syndrome (RLS) is unknown. Sensory and motor symptoms RLS worsen during evening/night, coincident with physiological peak pineal melatonin excretion. Decreased levels have been reported in insomnia, which an associated feature RLS. Melatonin substitution improved insomnia. A potential association between idiopathic (iRLS) alterations excretion was therefore explored. Daytime (7:00-22:00 hr) night-time (22:00-7:00 urinary 6-OH-melatonin-sulfate...
Objective . Violent dream content and its acting out during rapid eye movement sleep are considered distinctive for behaviour disorder (RBD). This study reports first quantitative data on dreaming in a cohort of patients with treated Wilson’s disease (WD) WD RBD. Methods Retrospective questionnaires different dimensions prospective two-week home diary self-rating emotions blinded, categorical rating by an external judge. Results showed significantly lower word count very few other...
Since the discovery of REM-sleep, modern empirical dream research has made considerable advances in making dreaming a subject scientific interest. To allow for quantification and interpretation material, it is necessary that at first dreamer him or herself able to reach an optimal notion experienced dream. This means predominantly seeing memorizing imagery. individual experience mainly preverbal secondarily converted into speech become communicable. The dreamer’s capacity observe imagery...
The continuity hypothesis states that waking life experiences, e.g., personal concerns and cultural environment, are reflected in dreams. present study’s goal was to compare written dream reports from Brazilian German samples. Overall, 97 participants were included; two samples previous studies (N=89 N=4197) selected for comparison. reported 328 the 348 diary In addition, 86 2893 most recent dreams compared. For both types of collected dreams, we found more bizarreness reports,...