A5042988571- Supramolecular Self-Assembly in Materials
- Luminescence and Fluorescent Materials
- Supramolecular Chemistry and Complexes
- Advanced biosensing and bioanalysis techniques
- Metal-Organic Frameworks: Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Innovative Microfluidic and Catalytic Techniques Innovation
- Molecular Sensors and Ion Detection
- Magnetism in coordination complexes
- Nanocluster Synthesis and Applications
- X-ray Diffraction in Crystallography
- Metal complexes synthesis and properties
- Microfluidic and Capillary Electrophoresis Applications
- 2D Materials and Applications
- Graphene and Nanomaterials Applications
- Aluminum Alloys Composites Properties
- Click Chemistry and Applications
- Covalent Organic Framework Applications
- Dendrimers and Hyperbranched Polymers
- Influenza Virus Research Studies
- Alzheimer's disease research and treatments
- Synthesis and Properties of Aromatic Compounds
- Graphene research and applications
- Electrowetting and Microfluidic Technologies
- Sulfur Compounds in Biology
East China Normal University
2023-2025
Shandong First Medical University
2025
Green Chemistry
2025
Shandong Provincial Hospital
2025
East China University of Science and Technology
2016-2024
Xi'an University of Architecture and Technology
2024
Chongqing Normal University
2023-2024
Second Military Medical University
2023
Nobel Foundation
2019-2020
A series of 3-hydroxyflavone (3-HF) ESIPT (excited-state intramolecular proton transfer) boronate-based fluorescent probes have been developed for the detection peroxynitrite (ONOO–). The dyes are environmentally sensitive, and each probe exhibited a ratiometric response toward ONOO– in micellar environment. were used to image different aggregation states amyloid-β (Aβ) presence ONOO–. 3-HF-OMe was found produce when bound Aβ aggregates, resulting novel host–guest ensemble, which adds...
Emerging liquid biopsy methods for investigating biomarkers in bodily fluids such as blood, saliva, or urine can be used to perform noninvasive cancer detection. However, the complexity and heterogeneity of exosomes require improved achieve desired sensitivity accuracy. Herein, we report our study on developing a breast system, including fluorescence sensor array deep learning (DL) tool AggMapNet. In particular, 12-unit composed conjugated polyelectrolytes, fluorophore-labeled peptides,...
Due to their precise three-dimensional structures and tunable cavities, metallacages covalent cages have been widely used in various fields, such as catalysis, separation, sensing, biomedicine. As a result of the unique pattern directed synthesis modular assembly, can be modified many different ways construct stimuli-responsive for marker detection imaging biological applications. Additionally, agents drugs loaded into cavity achieve disease diagnosis treatment. This Review summarizes recent...
In this highlight, we summarize the design principle and representative examples of MOCs for gas adsorption separation, with aim providing a theoretical basis designing more that can adsorb purify gas.
Abstract Structurally well‐defined graphene nanoribbons (GNRs) have attracted great interest because of their unique optical, electronic, and magnetic properties. However, strong π–π interactions within GNRs result in poor liquid‐phase dispersibility, which impedes further investigation these materials numerous research areas, including supramolecular self‐assembly. defined were synthesized by a bottom‐up strategy, involving grafting hydrophilic poly(ethylene oxide) (PEO) chains different...
Abstract Microfluidics has received extensive attention due to its ability rapidly prepare a large number of microdroplets with controlled sizes and defined morphologies. In addition having surface areas controllable confinement environments, these prepared can be used as analytical detection devices screen optimize various kinetic parameters. This review summarizes recent advances in the microfluidic control droplet‐based catalytic reactions discusses role droplets both homogeneous...
A 2D peptidosheet unravels CD47 as a potential biomarker to image hepatocarcinoma and cholangiocarcinoma cells tissues. Supramolecular assembly between water-soluble MoS2 peptide probe produces the suited for profiling of tissues over healthy on clinical specimens.
The five-year survival rate of hepatocellular carcinoma (HCC) remains unsatisfactory. This reflects, in part, the paucity effective methods that allow target-specific diagnosis and therapy HCC. Here, we report a strategy based on engineered human serum albumin (HSA) permits HCC-targeted delivery diagnostic therapeutic agents. Covalent cysteine conjugation combined with exploitation host–guest chemistry was used to effect orthogonal functionalization HSA two functionally independent peptides....
Developing a new strategy to improve the self-assembly efficiency of functional assemblies in confined space and construct hybrid materials is significant fascinating endeavor. Herein, we present highly efficient for achieving supramolecular well-defined metallacages microdroplets through continuous-flow microfluidic devices. The high versatility this approach are demonstrated by generation five representative different solvents containing water, DMF, acetonitrile, methanol few minutes with...
Principal component analysis of a fluorescent supramolecular sensor array based on graphene oxide can be used to differentiate ebola virus from marburg and receptor-extensive vesicular stomatitis virus.
ConspectusFluorescence by small molecular dyes is renowned for its real-time, dynamic, and noninvasive nature. It has become indispensable across scientific domains, including information storage, optoelectronic materials, biosensing, both diagnosing treating diseases. Despite their widespread use, these suffer from several limitations due to the sensitivity of photophysical properties environmental factors, such as concentration, solvent composition, polarity. These challenges particularly...
Chirality plays a vital role in material properties, and precise control of chiral signals is key to designing functional materials. Supramolecular self‐assembly offers an efficient means integrate building blocks with chromophores, yet controlling the assembly pathway remains challenging due complexity non‐covalent interactions. Here, we introduce continuous parallel‐laminar‐assisted strategy that exploits solvent ordering solute diffusion confined environments regulate multi‐component...
Chirality plays a vital role in material properties, and precise control of chiral signals is key to designing functional materials. Supramolecular self‐assembly offers an efficient means integrate building blocks with chromophores, yet controlling the assembly pathway remains challenging due complexity non‐covalent interactions. Here, we introduce continuous parallel‐laminar‐assisted strategy that exploits solvent ordering solute diffusion confined environments regulate multi‐component...
This paper discusses the use of N,N'-disubstituted-dihydrodibenzo[a,c]phenazines with typical Vibration-Induced-Emission (VIE) properties for imaging amyloid β (Aβ) fibrils, which are a signature neurological disorders such as Alzheimer's disease. A water-soluble VIEgen red fluorescence emission shows pronounced, blue-shifted Aβ peptide monomers and fibrils. The enhancement in blue can be ascribed to restriction molecular vibration by selectively binding Aβ. We determine an increasing...