- Immunotherapy and Immune Responses
- SARS-CoV-2 detection and testing
- Monoclonal and Polyclonal Antibodies Research
- SARS-CoV-2 and COVID-19 Research
- vaccines and immunoinformatics approaches
- Respiratory viral infections research
- Rabies epidemiology and control
- T-cell and B-cell Immunology
- Virus-based gene therapy research
- Prenatal Screening and Diagnostics
- Viral gastroenteritis research and epidemiology
- Reproductive System and Pregnancy
- Blood donation and transfusion practices
- Immune Cell Function and Interaction
- Virology and Viral Diseases
- Microbial infections and disease research
- Glycosylation and Glycoproteins Research
- Advanced Biosensing Techniques and Applications
- Social Media in Health Education
- Scientific Research and Philosophical Inquiry
- Ear Surgery and Otitis Media
- Facial Nerve Paralysis Treatment and Research
- Pregnancy and Medication Impact
- Cancer Genomics and Diagnostics
- Effects of Radiation Exposure
Central University Hospital of Asturias
2018-2025
Instituto de Investigación Sanitaria del Principado de Asturias
2020-2023
Misión Biológica de Galicia
2023
Hospital de São João
2005-2021
Universidad de Oviedo
2018
University of Chile
1972-2016
Universidade de São Paulo
2000-2014
Universidade Brasil
2014
In-Q-Tel
2005
University of British Columbia
1978-1989
<title>Abstract</title> During the last pandemic situation, availability of widest possible range diagnostic techniques was really important. Nowadays, RT-qPCR is gold-standard, but those based on immunochromatography for SARS-CoV-2 antigen detection are most used quick patient triage. However, there other that may be useful, as indirect immunofluorescence assays (IFA). The aim this study to stablish an IFA method direct nasopharyngeal samples. Results show total sensitivities between 34.55%...
The aim of this work was to assess the prevalence extended spectrum-β-lactamase (ESBL)- and carbapenemase-producing Enterobacteriaceae in fecal samples recovered from rural urban healthy dogs Northwest Spain (Galicia) identify potential high-risk clones molecularly characterize positive isolates regarding genes coding for ESBL/pAmpC resistance virulence. Thirty-five (19.6%) out 179 were cephalosporin-resistant Enterobacteriaceae, including Escherichiacoli Klebsiella pneumoniae (39 three...
The probabilistic record linkage (PRL) is based on a likelihood score that measures the degree of similarity several matching variables. Screening test results for different diseases are available blood donor population. In this paper, we describe accuracy PRL process used to track donors from Fundação Pró-Sangue (FPS) in Mortality Information System (SIM), order future studies might determine donor’s cause death. databases were SIM and database made up individuals living (200 2007) dead...
Abstract We have evaluated the contribution of host response with respect to transplantation immunity tumor-associated fetal antigens by a colony-forming unit technique liver test cells as source units (FCFU). To measure we effect immunization tumor on development colonies in spleens immunized, irradiated recipients. It could be demonstrated that syngeneic (plasmacytoma, MSV-BALB/3T3), allogeneic (EL4), or xenogeneic (SV40 hamster) was capable generating BALB/c recipients at least cytostatic...
Abstract Although it is well known that thymus function changes with age, not whether these are associated specific thymocyte populations. Since one criterion of specificity cell size, we studied the size distribution thymocytes from mice 0.5 days to 30.5 months age. Body weight, and yield were also measured. The mean volume 8.5 13 week old was 326 μ 3 , two detectable subpopulations. Mean found change During first postnatal week, whole population increased 200 350 percentage large cells...
Human antibodies to human or mouse fetal liver cell antigens have been demonstrated in the sera of patients harboring carcinoma breast, lung colon and malignant melanoma.In order define further clinical significance these tumor-associated anti-fetal antibodies, same indirect radioimmunoassay detection technique has used examine obtained during normal pregnancy.In addition, studies directed at immunochemical specificity underlying reaction.During pregnancy a specific pattern reactivity...
BACKGROUND:Peripheral facial paralysis is a clinical presentation which, in most cases, benign. It relatively frequent, although less so pediatric patients, where diagnosis more difficult. This condition can be congenital, neurological, infectious, neoplastic, traumatic, or metabolic origin. CASE REPORT:This report describes the case of male infant 23 months age with peripheral due to Epstein-Barr virus (EBV) upper respiratory infection. A hemogram showed presence leukocytosis and...
Thymocytes exposed in vivo to 200 R of X-rays 72 hr prior transplantation enhanced marrow growth almost twice that seen mice similarly treated with non-irradiated thymocytes. Growth was evaluated by the spleen colony-forming technique. These results confirm and extend previous data from this laboratory for which a cell-to-cell interaction has been postulated as basis augmentation bone The present show minimal effective ratio (thymocyte: cell) 8:1 irradiated thymocytes compared value 16:1 unirradiated
Mutational analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can quantify the relative importance variants over time, enable dominant mutations to be identified, and facilitate near real-time detection, comparison tracking evolving variants. SARS-CoV-2 in Asturias, an autonomous community Spain with a large ageing population, high levels migration tourism, was monitored tracked from beginning pandemic February 2020 until its decline stabilization August 2021, samples...
<title>Abstract</title> <bold>Purpose</bold>: Among the methods used to diagnose COVID-19, those based on genomic detection by q(RT)-PCR are most sensitive. To perform these assays, a previous genome extraction of sample is required. The dramatic increase in number SARS-CoV-2 assays has increased demand for reagents hindering supply commercial reagents. Homemade and procedures could be an alternative. <bold>Methods</bold>: Nasopharyngeal samples were extracted seven different as well...