A5064772362- Molecular spectroscopy and chirality
- Asymmetric Synthesis and Catalysis
- Analytical Chemistry and Chromatography
- Asymmetric Hydrogenation and Catalysis
- Crystallization and Solubility Studies
- Synthesis and Catalytic Reactions
- X-ray Diffraction in Crystallography
- Liquid Crystal Research Advancements
- Axial and Atropisomeric Chirality Synthesis
- Metabolomics and Mass Spectrometry Studies
- Advanced NMR Techniques and Applications
- Luminescence and Fluorescent Materials
- Spectroscopy and Chemometric Analyses
- Synthetic Organic Chemistry Methods
- Chemical Synthesis and Analysis
- Advanced Measurement and Detection Methods
- Acoustic Wave Phenomena Research
- Catalytic C–H Functionalization Methods
- Synthesis and Properties of Aromatic Compounds
- Spectroscopy and Quantum Chemical Studies
- Surface Chemistry and Catalysis
- Catalytic Cross-Coupling Reactions
- Organoboron and organosilicon chemistry
- Advanced biosensing and bioanalysis techniques
- Social Acceptance of Renewable Energy
Liaoning Shihua University
2025
Shangqiu Normal University
2011-2025
Chemical Synthesis Lab
2025
Sichuan University
2024
Zhengzhou University
2009-2024
Qingdao University of Science and Technology
2022-2023
China University of Mining and Technology
2023
Shaanxi University of Technology
2022
Beijing Zhongke Science and Technology (China)
2019-2022
Nanjing University of Science and Technology
2022
Abstract Residual dipolar couplings (RDCs) have attracted attention in light of their great impact on the structural elucidation organic molecules. However, effectiveness RDC measurements is limited by shortage alignment media compatible with widely used solvents, such as DMSO. Herein, we present first liquid crystal (LC) based medium that pure DMSO, thus enabling polar and intermediate polarity The crystals were obtained grafting polymer brushes onto graphene oxide (GO) using free radical...
Chiral discrimination is an indispensable tool that has pivotal importance in the assignment of absolute configuration and determination enantiomeric excess chiral compounds. A series enantiomerically pure trans-1,2-diaminocyclohexane (trans-DACH)-derived benzamides were first synthesized by simple chemical steps, 14 variated derivatives 6a-6n have been assessed as NMR solvating agents (CSAs) for signals mandelic acid (MA) 1H analysis. The highly efficient recognition CSA 6e on different...
ABSTRACT Determining the constitution and configuration is a critical step in characterizing structure of small molecules. In addition to classical nuclear magnetic resonance (NMR) method conducted isotropic solutions, emerging anisotropic NMR parameters such as residual dipolar couplings (RDCs) were also employed clarify structures organic These RDCs not only confirmed that unexpectedly synthesized product was quinazolinone but validated relative diastereoisomeric hydroindole...
Residual dipolar couplings (RDC) emerged to be an important structural parameter for organic and biomolecules. Herein, a new helical polyisocyanopeptide (l,l-PIAF-OBn) that forms lyotropic liquid crystals (LLC) in CDCl3 is proposed as novel weakly orienting medium acquiring residual (RDCs) of molecules. We demonstrate its application the elucidation strychnine triptolide.
Enantiopure diphenylprolinols have been developed as effective and practical NMR chiral solvating agents for the enantiodiscrimination of diverse α-carboxylic acids.
A general AzePhenol dinuclear zinc catalytic system has been successfully developed and introduced into the asymmetric addition of dimethylzinc alkynylzinc to aromatic aldehydes. In this system, an azetidine derived chiral ligand proven be effective enantioselective promoter. Under optimal reaction conditions, a series 1-hydroxyethyl (up 99% ee) secondary propargylic alcohols 96% were generated with good yields enantioselectivities. Additionally, novel showed functional group compatibility....
Abstract High‐damping acoustic composites with unique sound insulation feature is reported, demonstrating surprisingly stable soundproof properties over a wide bandwidth of frequency (63–6300 Hz) good mechanical properties. The extraordinary are attributed to the multiscale synergy lamellar and hollow structures by multifillers adding. designed fabricated through low‐temperature one‐time rubber mixing process using nitrile butadiene rubber(NBR), chloroprene (CR) as matrix mica powder (MP),...
The development of chiral alignment media for measuring anisotropic NMR parameters provides an opportunity to determine the absolute configuration molecules without need derivatization. However, with a high and robust enantiodiscriminating property wide range are still scarce. In this study, we synthesized cholesterol-end-functionalized helical polyisocyanides from monomer using cholesterol-based alkyne-Pd(II) initiator. These stereoregular form stable weak lyotropic liquid crystals (LLCs)...
Cinchona alkaloid derivatives as Brønsted base catalysts have attracted considerable attention in the field of asymmetric catalysis. However, their potential application chiral solvating agents has not been described. In this research, we investigated use dimer, namely, (DHQ)2PHAL, a agent for discerning various mandelic acid through 1H NMR spectroscopy. The addition catalytic amounts DMAP facilitated process. Our experimental results demonstrate that dimeric (DHQ)2PHAL exhibits remarkable...
A series of small-membered heterocycle probes, so-called azaheterocycle-containing diphenylmethanol chiral solvating agents (CSAs), have been developed for NMR enantiodiscrimination. These sensors were readily synthesized inexpensive and efficiently used the analysis alpha-substituted carboxylic acids. The sensing method was operationally simple processing straightforward. Notably, we propose (S)-aziridinyl as a promising CSA, which has excellent discriminating properties offers multiple...
Residual dipolar couplings (RDCs) have attracted attention in light of their great impact on the structural elucidation organic molecules. However, effectiveness RDC measurements is limited by shortage alignment media compatible with widely used solvents, such as DMSO. Herein, we present first liquid crystal (LC) based medium that pure DMSO, thus enabling polar and intermediate polarity The crystals were obtained grafting polymer brushes onto graphene oxide (GO) using free radical...
A bucket structure optimization method based on compound digging trajectory and limit force was proposed for the problem that real resistance of excavators is difficult to measure use as load optimization. The uncertainty in actual process excavator analyzed, a obtained by active using action. Based model, its variation law were calculated, analyzed different hydraulic cylinder’s trajectory. shape line equation, parametric model established APDL language, stress under actions analyzed. mass...
Dendrimer-supported ferrocenylmethyl aziridino alcohols have been developed and applied as efficient, recoverable recyclable catalysts in asymmetric catalysis.
A family of enantiopure β‐aminoalcohols based on aziridine backbones were synthesized, and examined as chiral ligands for the copper(II)‐catalyzed asymmetric Henry reaction aromatic aldehydes with nitromethane, giving β‐nitroalcohols in excellent yields (up to 93%) moderate good enantioselectivities 82%). Moreover, possible transition states are proposed. Copyright © 2014 John Wiley & Sons, Ltd.
A new optically active BINOL-amino alcohol has been designed and synthesized in a good yield applied as chiral nuclear magnetic resonance (NMR) solvating agent for enantioselective recognition. Analysis by 1H NMR spectroscopy demonstrated that it excellent enantiodifferentiation properties toward carboxylic acids non-steroidal anti-inflammatory drugs (14 examples). The non-equivalent chemical shifts (up to 0.641 ppm) of various mandelic were evaluated the reliable peak well-resolved signals....