A5101893842- Folate and B Vitamins Research
- Liver Disease Diagnosis and Treatment
- Synthesis and Catalytic Reactions
- Asymmetric Synthesis and Catalysis
- Research, Science, and Academia
- Hepatitis B Virus Studies
- Dementia and Cognitive Impairment Research
- Ferroptosis and cancer prognosis
- Hepatitis C virus research
- Cancer, Lipids, and Metabolism
- Synthetic Organic Chemistry Methods
- Genetic Associations and Epidemiology
- Aging, Elder Care, and Social Issues
- Asymmetric Hydrogenation and Catalysis
- RNA Research and Splicing
- RNA modifications and cancer
- Muscle activation and electromyography studies
- Cancer-related molecular mechanisms research
- Balance, Gait, and Falls Prevention
- Ubiquitin and proteasome pathways
- Intraoperative Neuromonitoring and Anesthetic Effects
- Economic Development and Digital Transformation
- Geriatric Care and Nursing Homes
- Stroke Rehabilitation and Recovery
- Sports Performance and Training
Guangxi Medical University
2017-2025
Henan Provincial People's Hospital
2021-2025
Second Affiliated Hospital of Guangzhou Medical University
2024
Guangdong Medical College
2024
Guangzhou Medical University
2024
Huazhong University of Science and Technology
2022-2023
Zhengzhou University
2014-2021
Henan University
2020
Tianjin University of Sport
2019
Shangqiu Normal University
2015
To identify genomic regions subject to positive selection that might contain genes involved in high-altitude adaptation (HAA), we performed a genome-wide scan by whole-genome sequencing of Tibetan highlanders and Han lowlanders. We revealed collection candidate located 30 loci under selection. Among them, MCUR1 at 6p23 was novel pronounced candidate. By single-cell RNA comprehensive functional studies, demonstrated depletion leads impairment erythropoiesis hypoxia normoxia. Mechanistically,...
The performance of the real-time dynamic force and torque compensation, flexible interactive control, ability to compensate for defect passive rehabilitation training are important functions within robot design process. In this investigation, upper limb is designed, sensor used measure joint feedback with high precision, sensitivity, low cost. process, human–machine adaptability lightweight driving considered, static moment detection performances analyzed. Furthermore, impedance control...
Abstract The sodium taurocholate cotransporting polypeptide (NTCP) encoded by SLC10A1 was recently demonstrated to be a functional receptor for hepatitis B virus (HBV). role of polymorphisms, particularly the Ser267Phe variant (rs2296651) in exon 4, has been frequently investigated regard risk persistent HBV infection. However, these investigations have generated conflicting results. To examine whether common genetic variation at locus is associated with infection, haplotype-tagging and...
A family of enantiopure β‐aminoalcohols based on aziridine backbones were synthesized, and examined as chiral ligands for the copper(II)‐catalyzed asymmetric Henry reaction aromatic aldehydes with nitromethane, giving β‐nitroalcohols in excellent yields (up to 93%) moderate good enantioselectivities 82%). Moreover, possible transition states are proposed. Copyright © 2014 John Wiley & Sons, Ltd.
Falls are a major public health problem, especially for older people. This research aimed to provide direct illustration of fall risks among the homebound people with dementia in China, and identify risk factors associated it. In 2020, questionnaire-based field survey was used assess 1,042 aged over 60 years Ningbo, Eastern China. The Morse Fall Risk Scale's result employed as dependent variable, while basic problems, living environment difficulties, social support behavioral awareness...
Spinal cord ischemic-reperfusion injury (SCIRI) could occurs during surgical procedures without detection, presenting a complex course and an unfavorable prognosis. This may lead to postoperative sensory or motor dysfunction in areas innervated by the spinal cord, some cases, permanent paralysis. Timely detection of SCIRI immediate waring can help surgeons implement remedial intervention prevent irreversible injury. Therefore, it is crucial develop precise effective method for early SCIRI....
Background Agitation is common among older adults with dementia, negatively affecting their quality of life and caregivers’. Since home care remains the dominant approach for adults, this study investigates risk factors agitation in dementia China. Methods We perform a cross-sectional home-cared Ningbo, China, using 2020 data. use self-made questionnaire to investigate risks agitated behavior its related factors. descriptive, univariate, regression analyses. Findings address 640 Chinese...
Hepatocellular carcinoma (HCC) is the fifth most common cancer and second cause of cancer-related deaths worldwide. As immune response failure main factor in occurrence poor prognosis HCC, our study aimed to develop an immune-associated molecular predictor (IMOPP) HCC. To that end, we discovered a 4-gene gene signature: C–C motif chemokine ligand 14 (CCL14), kallikrein B1 (KLKB1), vasoactive intestinal peptide receptor 1 (VIPR1), cluster differentiation 4 (CD4). When tested on three cohorts...
Background: Agitation is common among older adults with dementia, negatively affecting their quality of life and caregivers’. Since home care remains the dominant approach for adults, this study investigates risk factors agitation in dementia China.Methods: We perform a cross-sectional home-cared Ningbo, China, using 2020 data. use self-made questionnaire to investigate risks agitated behavior its related factors. descriptive, univariate, regression analyses.Findings: address 876 Chinese...
Background: Increasing evidence has highlighted the role of ubiquitin-like PHD and RING finger domain-containing protein 1 (UHRF1) in development cancers, including hepatocellular carcinoma, pancreatic cancer, bladder cancer. However, correlation between UHRF1 breast cancer remains unclear. The present study aimed to analyze expression its invasive ductal (IDC) by integrating multilevel data immunohistochemistry analysis. Methods: Gene Expression Omnibus (GEO) Cancer Genome Atlas (TCGA)...
To explore aerobic power and energy expenditure of high level rugby players in China, which provide experimental basis for accurate training nutritional strategy match-play.Eighteen master were selected as research subjects. The parameters such VO2max, lactic aicd threshold (LT) modify conconi test measured respectively. differences compared between the forward defender. data analyzed by independent sample t test.The VO2max(42.05±3.69 ml/min ·kg-1) was poorer. VO2max 38.83±3.52 (ml/min...
Abstract A novel type of aziridine based ligands is synthesized and the derivative LIG successfully applied under optimized conditions for enantioselective Henry reaction aromatic aldehydes (I).
Abstract The enantiopure aziridine carbinol ligands are easily prepared in five steps from commercially available starting materials and successfully used as catalyst the synthesis of chiral secondary alcohols.
<div>Abstract<p><b>Purpose:</b> Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. In China, chronic hepatitis B virus (HBV) infection remains major risk factor for HCC. this study, we performed a genome-wide association study (GWAS) among Chinese populations to identify novel genetic loci contributing susceptibility HBV-related HCC.</p><p><b>Experimental Design:</b> GWAS scan in collection 205 HCC trios (each trio...
<div>Abstract<p><b>Purpose:</b> Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. In China, chronic hepatitis B virus (HBV) infection remains major risk factor for HCC. this study, we performed a genome-wide association study (GWAS) among Chinese populations to identify novel genetic loci contributing susceptibility HBV-related HCC.</p><p><b>Experimental Design:</b> GWAS scan in collection 205 HCC trios (each trio...
Objective: The aims of present study are to develop a molecular predictor associated with immune response for predicting the tumorigenesis and prognosis HCC.Methods: We separately established training cohort, validating low AFP cohort HCC GSE14520 GSE 36376. Then, we analyzed different gene signature by means bioconductor software developed predictors machine learning. occurrence was evaluated ROC curve survival analysis.Results: discrimination tissue adjacent have higher specificity...