A5068280065- Inflammatory Bowel Disease
- Microscopic Colitis
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Screening and Detection
- Pregnancy and Medication Impact
- Dysphagia Assessment and Management
- Genetic factors in colorectal cancer
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Pancreatitis Pathology and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Neuroendocrine Tumor Research Advances
- COVID-19 and healthcare impacts
- Colorectal Cancer Surgical Treatments
- Biosimilars and Bioanalytical Methods
- Cancer Genomics and Diagnostics
- COVID-19 Clinical Research Studies
- Autoimmune and Inflammatory Disorders
- Head and Neck Surgical Oncology
- Intraperitoneal and Appendiceal Malignancies
- Colorectal and Anal Carcinomas
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
Hospital Beatriz Ângelo
2016-2024
Hospital da Luz
2024
IPO Porto
2015
University Gastroenterology
2013
Instituto Português de Oncologia de Coimbra Francisco Gentil
2010
University of Calgary
2009
This is the second of a series two articles reporting European Crohn's and Colitis Organisation [ECCO] evidence-based consensus on management adult patients with ulcerative colitis [UC]. The first article focused medical management, present addresses treatment acute severe [ASUC] surgical medically refractory UC patients, including preoperative optimisation, strategies, technical issues. provides advice for variety common clinical conditions. Together, represent an update recommendations ECCO UC.
Abstract This article is the second in a series of two publications on European Crohn’s and Colitis Organisation [ECCO] evidence-based consensus management disease. The first covers medical management; present addresses surgical management, including preoperative aspects drug before surgery. It also provides technical advice for variety common clinical situations. Both articles together represent recommendations ECCO disease an update prior Guidelines.
Abstract The management of inflammatory bowel disease [IBD] is complex, and requires tight control activity, close monitoring to avoid treatment side effects, health care professionals with expertise in IBD, an interdisciplinary, holistic approach. Despite various efforts standardise structures, processes, outcomes,1–8 due the high variability at local, national, international levels, there are still no clear definitions or outcome measures available establish quality standards for IBD...
The aim was to evaluate the presence of metabolic bone disease (MBD) in patients with Crohn's (CD) and identify potential etiologic factors.The case-control study included 99 CD 56 controls a similar age gender distribution. Both groups had dual-energy x-ray absorptionmetry nutritional evaluation. Single nucleotide polymorphisms at IL1, TNF-α, LTα, IL-6 genes were analyzed only. Statistical analysis performed using SPSS software.The prevalence MBD significantly higher (P = 0.006)....
<b><i>Background:</i></b> Colorectal cancer (CRC) is the first cause of cancer-related mortality in Portugal. CRC screening reduces disease-specific mortality. Colonoscopy currently preferred method for as it may contribute to reduction incidence. This beneficial effect strongly associated with adenoma detection rate (ADR). <b><i>Aim:</i></b> Our aim was evaluate quality colonoscopy at our unit by measuring accepted parameters and publish them...
Abstract Background Significant advances have been made in understanding the preclinical stages of IBD, and identifying risk factors biomarkers to predict IBD onset. With use predictive testing identify patients at developing disease, it would be possible intervene try mitigate that risk. However, feasibility such strategy, depend on whether individuals willing undergo preventive interventions. Methods A Redcap® electronic survey, available five languages, was disseminated by clinicians...
Adenomyomatosis is a rare benign lesion that has been observed in different sites throughout the gastrointestinal tract, most frequently gallbladder. Few cases have described stomach, small bowel, bile ducts, and ampullary region. Adenomyomas of vaterian system (ampulla common duct) important clinical consequences, since majority these lesions present with biliary tract obstruction mimic malignant behavior. As consequence, considering diagnostic difficulty lesions, patients are often treated...
Abstract Background Recently, the European Crohn’s and Colitis Organisation (ECCO) Consensus on Quality-of-Care (QoC) Standards proposed essential criteria structure of units who manage patients with inflammatory bowel disease (IBD)1. The E-QUALITY taskforce investigated whether there is a gap between given recommendations real-world IBD across ECCO-affiliated countries. Methods task force developed web survey accessible to all institutions affiliated ECCO Europe. Each institution was...
We report a case of patient with renal cell carcinoma on pazopanib, who presented severe upper gastrointestinal bleeding. Endoscopy showed giant bulbar ulcer visible vessel 4 mm. Due to unavailability surgical rescue backup, large calibre treatment was delayed. repeated after 48 hours and reduction in the diameter. Endoscopic adrenalin injection electrocoagulation were performed. However, increased size became pulsatile. The operated, confirming penetrating pancreas active bleeding from...
Familial adenomatous polyposis (FAP) and Crohn's disease (CD) are two entities with no known etiologic or physiopathogenic relation. The rarity of the former makes coincidence both diagnoses in one patient very unlikely. Nevertheless, management such cases can be puzzling as surgical options must considered, immunosuppression/immunomodulation is set a territory accelerated carcinogenesis. We report case 29-year-old male diagnosis FAP since adolescence, already submitted to prophylactic...
The World Health Organization reviewed the classification for serrated colonic polyps in 2010. A new entity, sessile adenoma, was included with two variants: and without cytological dysplasia. This lesion's malignant potential has been recognized according to classification, many may be reclassified. impact of this change is yet assessed.Analyze proportion lesions that were reclassified variables influenced it.Every patient at least one adenoma diagnosed a 5 year period included. All...
Abstract Background Current treatment goals in inflammatory bowel disease include clinical remission and endoscopic healing. A new concept of clearance (DC) is emerging as a therapeutic target ulcerative colitis (UC). Although not yet clearly defined, it reflects combination clinical, endoscopic, histological remission1. Preliminary data suggest that DC achievable with biologic therapy. Aim: to evaluate if patients treated with, 5-ASA can maintain sustained the incidence negative outcomes....
Introduction The incidence of chronic progressive diseases is rising and investment on quality death dying utmost importance to minimize physical emotional suffering. There still a gap in palliative care (PC) between patients with cancer those advanced liver disease (ACLD). Our objectives were characterize clinical attitudes therapeutic interventions evaluate the differences end-of-life inpatients ACLD under gastroenterology care. Methods Retrospective cohort study, including or who died...
Abstract Background The European Crohn’s and Colitis Organisation (ECCO) Position Paper on Quality-of-Care (QoC) proposed essential standards process outcomes for units that manage patients with inflammatory bowel disease (IBD). E-QUALITY taskforce investigated whether gaps between these real-world practice exist. Methods A 74-question web survey accessible to all institutions affiliated ECCO was developed. One delegate per institution requested respond. descriptive analysis done. Results...
Aims Endoscopic ultrasound fine needle biopsy (EUS-FNB) is the preferred method for sampling solid lesions in digestive wall or adjacent organs. Strategies to enhance its efficacy have been explored, with recent studies indicating that Macroscopic On-Site Evaluation (MOSE) by an echoendoscopist can be comparable Rapid On-site (ROSE) anatomopathologist. This study aims assess performance of MOSE EUS-FNB, specifically using 22G Franseen needle.
Pancreatic ductal adenocarcinoma (PDAC) incidence is rising, and prognosis remains poor due to late diagnosis limited effective therapies. Currently, patients are treated based on TNM staging, without molecular tumor characterization. This study aimed validate a technique that combines the amplification refractory mutation system (ARMS) with high-resolution melting analysis (HRMA) for detecting mutations in codon 12 of KRAS plasma, assess its prognostic value.
<b><i>Introduction:</i></b> Patients with inflammatory bowel disease (IBD) do not seem to be at increased risk of infection by SARS-CoV-2, but there is a concern whether immunosuppressive therapy may associated more severe disease. Several clinical practice recommendations have been published help guide IBD care during the COVID-19 pandemic. Nonetheless, few studies addressed patients’ perspectives and fears. We aimed evaluate Portuguese on management their SARS-CoV-2...