A5046354968- Reproductive Biology and Fertility
- BRCA gene mutations in cancer
- Breast Cancer Treatment Studies
- Advanced Breast Cancer Therapies
- Nutrition, Genetics, and Disease
- Renal and related cancers
- Breast Lesions and Carcinomas
- Global Cancer Incidence and Screening
- Bioenergy crop production and management
- Cancer Risks and Factors
- Ovarian function and disorders
- Cancer Diagnosis and Treatment
- Reproductive Health and Technologies
Ministry of Health of the Russian Federation
2022
Cancer Research Center
2014
В статье представлены результаты голосования I Cанкт-Петербургского международного консенсуса по диагностике и лечению рака молочной железы «Белые ночи 2024», посвященного наиболее актуальным спорным вопросам диагностики, хирургической тактики, лучевой терапии системного лечения данной категории пациентов. Под председательством член-корреспондента РАН, профессора Владимира Федоровича Семиглазова в международном консенсусе приняли участие 38 экспертов области диагностики (РМЖ),...
В последние годы в онкологии с внедрением новых методов комплексного лечения отмечается значительное увеличение продолжительности жизни пациентов. При этом большинство используемых потенциально гонадотоксичны и приводят к преждевременной недостаточности яичников, соответственно потере фертильности способности деторождению у молодых женщин. На момент постановки диагноза все больше пациенток задают вопросы о снижающим фертильность действии лекарственной терапии, радиотерапии, хирургических...
A group of reproductive age patients whose disease is associated with the carriage BRCA1 gene mutation scientific interest. Differences in molecular pathogenesis between BRCA-associated breast cancer and sporadic counterpart might presuppose anamnesis features each as well. We have ascertained that mean young positive status 31.8 ± 3.3 years, 40 % cases family history 1st 2 nd order relatives a was identified, diagnosed during pregnancy, feeding or 1 year post-pregnancy, course...
Purpose of the study. To determine and compare diagnostic efficacy planar scintigraphy, SPECT (including SPECT/CT) intraoperative gamma probe radiometry in detection sentinel lymph nodes (SLN) patients with breast cancer. Material methods. The study included 200 diagnosed cancer who underwent SLN biopsy period 2020–2021. identify s, all lymphoscintigraphy a 99mtc-labeled colloidal radiopharmaceutical one day before surgery. Planar was performed on into study, 181 examination volume or...
Purpose: To develop a method for evaluation of the radiation dose an embryo/fetus during lymphoscintigraphy (sentinel lymph node mapping) in pregnant patients with breast cancer. Material and methods: Two women (aged 43 30) cancer stage IIA (T 2 N 0 M ), second trimester pregnancy. We used lymphotropic colloidal radiopharmaceutical labeled 99m Tc. evaluate embryo, each patient had 6 individual dosimeters, which were placed around abdomen using elastic bandage at equal distances abdomen....
The problems in the early diagnosis, primary and secondary prevention of family cancer breast and/or ovaries are successfully solved within medical genetic counseling at a clinic. Its diagnosis is confirmed, individual risks for ovarian calculated, risk-modifying factors studied, treatment, planning, childbirth discussed during clinicogenetic studies.
To solve the problem of preserving reproductive function in cancer patients is very urgent today because antitumor treatment comprising different combinations radio- and chemotherapy surgery lead to ovarian reserve depletion premature menopause repro- ductive-aged women. The authors propose consider one fertility preservation techniques – tissue cryopreservation. A procedure for cryopreservation described detail; its efficiency evaluated. In authors’ opinion, this most promising sexual...
During last years one should note an unstoppable increase of the breast cancer incidence among patients reproductive age. A group pa- tients young age with whose disease is associated BRCA1/2 genes particular scientific interest. However, until now no single opinion on survival results in given oncological has been evolved yet. In this article, preliminary data general and non-recurrence are given, depending BRCA1 gene status.