A5038833464- Gut microbiota and health
- Allergic Rhinitis and Sensitization
- Muscle Physiology and Disorders
- Microbial Community Ecology and Physiology
- Meat and Animal Product Quality
- Neurogenetic and Muscular Disorders Research
- Pediatric health and respiratory diseases
- Asthma and respiratory diseases
- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Effects of Environmental Stressors on Livestock
- Muscle metabolism and nutrition
- Bacterial Infections and Vaccines
- Protist diversity and phylogeny
- Dermatology and Skin Diseases
Nonalcoholic steatohepatitis (NASH) is an advanced nonalcoholic fatty liver disease characterized by chronic inflammation and fibrosis. A dysbiosis of the gut microbiota has been associated with pathophysiology NASH, probiotics have proven helpful in its treatment prevention. Although both traditional next-generation potential to alleviate various diseases, studies that observe therapeutic effect on NASH are lacking. Therefore, we investigated whether a probiotic candidate, Faecalibacterium...
Akkermansia muciniphila, a promising candidate for next-generation probiotics, exhibits significant genomic diversity, classified into several distinct clades (AmI to AmIV). Notably, single clade tends predominate within individual hosts, with co-occurrence of different being rare. The mechanisms driving such clade-specific exclusion remain unclear. Here, we show that extracellular vesicles (EVs) derived from AmII inhibit the growth I (AmI), conferring competitive advantage AmII. Moreover,...
Allergic asthma (AA) is a common inflammatory airway disease characterized by increased hyper-responsiveness (AHR), inflammation, and remodeling. Akkermansia muciniphila strictly anaerobic bacterium residing in the gut promising next-generation probiotic to improve metabolic syndrome. A recent study suggested beneficial effect of live A. on allergic inflammation (AAI) mice. However, whether heat-killed form can AAI requires further investigation. Mice sensitized challenged with house dust...
Abstract Atopic dermatitis (AD) is a common inflammatory skin disease, and its pathogenesis closely associated with microbial homeostasis in the gut, namely gut-skin axis. Particularly, recent metagenomics studies revealed that abundance of two major bacterial species Faecalibacterium prausnitzii Akkermansia muciniphila , may play critical role AD, but effect these AD has not yet been elucidated. To evaluate potential beneficial F. or A. we conducted an animal model study where EB-FPDK11...
Muscular atrophy is a muscle disease in which mass and strength decrease due to aging, injury, metabolic disorders, or chronic conditions. Proteins tissue are degraded by the ubiquitin-proteasome pathway, accelerates this pathway. Akkermansia muciniphila Faecalibacterium prausnitzii strains effective agents against inflammatory diseases next-generation probiotic research. In study, we evaluated efficacy of A. strain EB-AMDK19 F. EB-FPDK11 mouse model muscular atrophy, since inhibits energy...
Obesity is a major health problem in dogs and strongly associated with an increased risk of chronic inflammatory metabolic diseases. The microaerophilic human gut bacterium