Olga Benítez
- Inflammatory Bowel Disease
- Hepatitis B Virus Studies
- Microscopic Colitis
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Autoimmune and Inflammatory Disorders
- Diagnosis and treatment of tuberculosis
- Venous Thromboembolism Diagnosis and Management
- Chemotherapy-induced cardiotoxicity and mitigation
- Diverticular Disease and Complications
- Liver Disease Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Immunodeficiency and Autoimmune Disorders
- Pregnancy and Medication Impact
- Nutrition and Health in Aging
- Vaccine Coverage and Hesitancy
- Folate and B Vitamins Research
- E-Learning and Knowledge Management
- Obesity and Health Practices
- Transplantation: Methods and Outcomes
- Liver Diseases and Immunity
- Mycobacterium research and diagnosis
- Appendicitis Diagnosis and Management
- Acute Lymphoblastic Leukemia research
- Celiac Disease Research and Management
Mútua Terrassa
2015-2024
Advocate Heart Institute
2023
Vall d'Hebron Hospital Universitari
2023
University Hospital Mútua de Terrassa
2022
Centro de Investigación Biomédica en Red
2015-2020
Hospital Regional Universitario de Málaga
2017-2018
Instituto de Hematología e Inmunología
2007
There is controversy as to whether the risk of relevant infection in IBD related immunosuppressants or disease itself. The aims this study were evaluate: [1] life-long prevalence and types infections patients with immunosuppressive treatment, [2] relationship both patient comorbidity mortality.Observational multicentre retrospective that presented a infection. For each case, four periods exposure analysed: P1: pre-IBD diagnosis, P2: from diagnosis immunosuppressant initiation, P3: during...
Abstract Background Anti–tumor necrosis factor agents (anti-TNFs) are efficacious at preventing the postoperative recurrence (POR) of Crohn disease, as demonstrated in 2 randomized controlled trials. However, real-life data for infliximab or adalimumab this setting scarce. Our aim was to assess both efficiency anti-TNFs early POR disease clinical practice and associated risk factors POR. Methods Patients whom were prescribed prevention within 3 months after ileocolonic resection who had an...
INTRODUCTION: The prevalence of penetrating complications in Crohn's disease (CD) increases progressively over time, but evidence on the medical treatment this setting is limited. aim study was to evaluate effectiveness biologic agents CD complicated with internal fistulizing disease. METHODS: Adult patients CD-related fistulae who received at least 1 agent for condition from prospectively maintained ENEIDA registry were included. Exclusion criteria involved those receiving biologics...
We aim to describe the incidence and source of contagion COVID-19 in patients with IBD, as well risk factors for a severe course long-term sequelae. This is prospective observational study IBD included ENEIDA registry (53,682 from 73 centres) between March-July 2020 followed-up 12 months. Results were compared data general population (National Centre Epidemiology Catalonia). A total 482 identified. Twenty-eight percent infected work environment, 48% by intrafamilial transmission, despite...
INTRODUCTION: To compare Engerix-B and Fendrix hepatitis B virus for primo vaccination in inflammatory bowel disease (IBD). METHODS: Patients with IBD were randomized 1:1 to receive double dose or single at months 0, 1, 2, 6. Anti-HBs titers measured 2 after the third fourth doses. Response was defined as anti-HBs ≥100 UI/L. doses again 6 12 dose. RESULTS: A total of 173 patients (54% received 46% Fendrix). Overall, 45% responded (anti-HBs IU/L) 3 71% The response rate 75% vs 68% ( P = 0.3)....
(1) Scant information is available concerning the characteristics that may favour acquisition of COVID-19 in patients with inflammatory bowel disease (IBD). Therefore, aim this study was to assess these differences between infected and noninfected IBD. (2) This nationwide case−control evaluated (cases) without (controls) during period March−July 2020 included ENEIDA GETECCU. (3) A total 496 cases 964 controls from 73 Spanish centres were included. No found basal controls. Cases had higher...
Conclusion(s): Direct inhibitors of activated factor X administration significantly affects the determination antithrombin by AT (Xa) method.At higher levels drug, determined level reached normal range and thus thrombophilic state was underestimated.If patient with mentioned deficiency is treated Apixaban, it more appropriate to use method (IIa) or laboratory methodology a DOAC stop tablet for control.
Abstract Background The true effect of having IBD in the development infections has not been studied depth since cohort studies are scarce and results sometimes contradictory. Especially, this complication addressed prospectively an incident patients with IBD. Aims To assess, regarding IBD: 1) incidence type, 2) risk factors, 3) type duration treatment, 4) impact mortality 5) activity. Methods INFEII registry (ClinicalTrials.gov: NCT02904590) is a prospective study promoted by GETECCU to...
Patients with inflammatory bowel disease (IBD) may require different immunosuppressive treatments throughout their illness. It is essential to assess the immunization status of patients at diagnosis or, if this not possible, least before beginning therapy and, subsequently, administering appropriate vaccines. Therefore, aim work establish clear and concise recommendations on vaccination in IBD settings our clinical practice including children, during pregnancy, breastfeeding or trips. This...
Abstract Background INFEII registry (ClinicalTrials.gov: NCT02904590) is a prospective study promoted by GETECCU to determine the incidence and risk factors of infection in an inception cohort IBD patients. Despite preventive measures recommendations scientific societies, TB remains problem patients with treated immunosuppressants (IMM) biologics. AIMS To asses: (1) screening performed at time inclusion patient registry, (2) latent TB; (3) compliance national European recommendations....
Background: Pediatric pulmonary embolism (PE) is rare but can be lifethreatening.Improving awareness of those managing pediatric patients may lead to faster identification and management with improved survival.Risktaking behavior that promote hypercoagulability should considered.Aims: We aim emphasize importance multidisciplinary collaboration in cases critical thrombosis.Methods: reviewed a PE case.Results: A 17-year-old male no medical history presented acute chest pain respiratory...
Abstract Background The prevalence of penetrating disease in Crohn’s (CD) increases progressively over time, and evidence on the medical treatment this complication is limited. aim study was to evaluate efficacy biologic agents CD complicated with internal fistulising disease. Methods A retrospective analysis all adult patients from ENEIDA registry (>68,000 patients) who received at least one agent -anti-TNF, ustekinumab or vedolizumab- for performed. Exclusion criteria comprised...
Abstract Background The information regarding IBD patients with COVID-19 suggests that the factors related to bad outcome are older age and comorbidity whereas immunosuppressants do not have a significant impact worsening disease evolution. To date, there is no assess if differences in epidemiological, demographical, clinical characteristics between infected non-infected patients. Methods Case-control study (cases) compared without (controls) period March-July/2020 within ENEIDA registry...