A5025876358- Fullerene Chemistry and Applications
- Microbial Natural Products and Biosynthesis
- Nanoplatforms for cancer theranostics
- Graphene research and applications
- Marine Sponges and Natural Products
- Biosensors and Analytical Detection
- Fungal Biology and Applications
- Graphene and Nanomaterials Applications
- Diamond and Carbon-based Materials Research
- Nanoparticle-Based Drug Delivery
- Microbial Metabolism and Applications
- Cancer-related molecular mechanisms research
- Luminescence and Fluorescent Materials
- Genomics and Phylogenetic Studies
- Synthesis and Properties of Aromatic Compounds
- Boron and Carbon Nanomaterials Research
- Advanced biosensing and bioanalysis techniques
- Supramolecular Self-Assembly in Materials
- Chemical Synthesis and Analysis
- Cancer Mechanisms and Therapy
- Advanced Biosensing Techniques and Applications
- Flame retardant materials and properties
- 3D Printing in Biomedical Research
- Lung Cancer Treatments and Mutations
- Medical and Biological Ozone Research
Wuhan University
2024-2025
Renmin Hospital of Wuhan University
2025
City University of Hong Kong, Shenzhen Research Institute
2024-2025
Peking University
2025
Peking University Third Hospital
2025
Capital Normal University
2025
Minzu University of China
2025
Zhejiang Ocean University
2021-2024
Zhejiang University
2021-2024
Henan Agricultural University
2023-2024
Abstract Surface modification of nanomaterials is essential for their biomedical applications owing to passive immune clearance and damage reticuloendothelial systems. Recently, a cell membrane‐coating technology has been proposed as an ideal approach modify its facile functionalized process good biocompatibility improving performances synthetic nanomaterials. Here, recent advances membrane‐coated are reviewed based on the main biological functions membrane in living cells. An overview...
The endohedral fullerene Sc3NC@C80-Ih has been synthesized and characterized; it an unprecedented planar quinary cluster in a cage. It is also the first chemical compound which presence of (NC)3− trianion disclosed. fascinating intramolecular dynamics enables whole molecule to display high polarity promising ferroelectricity. This finding inspires possibility that such may be useful constructing many other fullerenes.
Abstract The efficiency of polymer solar cells (PSCs) can be essentially enhanced by improving the performance electron‐acceptor materials, including increasing lowest unoccupied molecular orbital (LUMO) level, optical absorption, and tuning material solubility. Here, a new soluble C 70 derivative, dihydronaphthyl‐based bisadduct (NC BA), is synthesized explored as acceptor in PSCs. NC BA has high LUMO energy level that 0.2 eV higher than [6,6]‐phenyl‐C 61 ‐butyric acid methyl ester (PCBM),...
We present a metal carbide clusterfullerene Sc2C2@Cs(10528)–C72, whose structure has been baffling for many years. A motional endohedral Sc2C2 cluster, special molecule geometry and electronic were found in Sc2C2@Cs(10528)–C72. The paramagnetic Sc2C2@Cs–C72 anion radical was successfully prepared by chemical reduction method hyperfine couplings the ESR spectrum observed.
Following the first isolation of Sc3NC@C80, a second member this family endohedral metallofullerenes, Sc3NC@C78, was prepared by an arc-discharging method. Experimental and theoretical studies demonstrated that Sc3NC@C78 has C78-C2 cage with two pairs adjacent pentagons, which is different from IPR-satisfying Sc3N@C78-D3h. It revealed size C78-D3h appropriate for Sc3N cluster, but not large enough encaging planar species Sc3NC. Theoretical calculations were preformed on Sc3NC@C78-C2...
Highly impressionable electron spin was found in endohedral azafullerene Y(2)@C(79)N at low temperature or upon exohedral chemical modification. These external stimulations can be employed to manipulate the spin-active and further used quantum processes for promising information-carrying systems molecular devices.
// Yihan Ma 1 , Xiaoyan Pan 1, 2 Peiqi Xu 3 Yanjun Mi Wenyi Wang Xiaoting Wu Qi He Xinli Liu Weiwei Tang and Han-Xiang An Xiamen Cancer Hospital the First Affiliated of University, 361003 Fujian, China Department Medical Oncology, Linyi Hospital, 276000 Shandong, Reproduction Center, The Second Kunming 650101 Yunnan, Correspondence to: An, email: anhanxiang@xmu.edu.cn Keywords: EGFR, EGFR-TKI, NSCLC, circulating miRNA, primary resistance Received: November 02, 2016 Accepted: July 18, 2017...
Early detection and treatment of Streptococcus pneumoniae (SPN) is crucial for patients. However, since nucleic acid testing relies on large-scale equipment specialized operators, challenges remain accurate, fast, low-cost SPN detection. Here, we present a point-of-care (POCT) device rapid accurate based low-frequency optical signal enhancement cluster regularly interspaced short palindromic repeats (CRISPR). The spotlight tube enables the fluorescence signal, while combination an artificial...
Rational design and modification of the all-carbon fullerene cages to meliorate their nature hydrophobicity is critical for biomedical applications. The outstanding electron affinity fullerenes enables them effectively eliminate reactive oxygen species (ROS), excess which may lead health hazards or biological dysfunction. Herein reported a facile, mild, green approach synthesizing favorable water-soluble C60 nanoparticles capable ROS-scavenging by combining mussel-inspired chemistry with...
Natural product discovery is hindered by the lack of tools that integrate untargeted nuclear magnetic resonance and mass spectrometry data on a library scale. This article describes first application innovative NMR/MS-based machine learning tool, "Structure-Oriented Fractions Screening Platform (SFSP)", enabling functional-group-guided fractionation accelerating characterization undescribed natural products. The concept was applied to extract marine fungus known be prolific producer diverse...
We report the preparation, isolation, and spectroscopic characterizations of a novel endofullerene Lu3C2@C88, where planar trimetallic carbide cluster Lu3C2 is encapsulated by D2-symmetric C88 cage. Meanwhile, nitride Lu3N@C88 was also isolated characterized for comparison. The results revealed that both metal Lu3N share same Theoretical studies internal moieties supply cage with six electrons in Lu3C2@C88 cases; however, has closed-shell electronic structure owns an unpaired electron...
A new metallofullerene Y3N@C78-C2 was synthesized and characterized. It shown that Y3N@C78 has an unconventional C78-C2 cage with two pairs of fused pentagons closely bonded yttrium atoms. DFT calculations showed the size ionic radii metals forming caged cluster plays important role in non-isolated-pentagon-rule-feature C78 cage.
Marine fungi-derived natural products represent an excellent reservoir for the discovery of novel lead compounds with biological activities. Here, we report identification two new drimane sesquiterpenes (1 and 2) six polyketides (3-8), together 10 known (9-18), from a marine-derived fungus Penicillium sp. TW58-16. The planar structures these were elucidated by extensive 1D 2D NMR, which was supported HR-ESI-MS data. absolute configurations determined experimental calculated electronic...
Abstract Chemo‐photodynamic therapy is an attractive strategy in tumor treatment. However, the combination of chemotherapeutic drug and photosensitizer nanocarriers always elevates risk composition uncertainty. Here, a dual‐targeting photosensitizer‐peptide amphiphile conjugate (PpIX‐GGGK(TPP)GG‐GFLG‐R 7 ‐RGD or pPAC) designed to encapsulate doxorubicin (DOX) for enhanced chemo‐photodynamic therapy. The amphiphilic nature pPAC leads formation core‐shell structured nanomicelles aqueous media,...