A5016502825- Liver Diseases and Immunity
- SARS-CoV-2 and COVID-19 Research
- Liver Disease Diagnosis and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Renal Transplantation Outcomes and Treatments
- Hepatitis Viruses Studies and Epidemiology
- Hepatitis B Virus Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal function and acid-base balance
- Chronic Myeloid Leukemia Treatments
- Orthopedic Infections and Treatments
- Hemodynamic Monitoring and Therapy
- Organ Transplantation Techniques and Outcomes
- COVID-19 Clinical Research Studies
- Diabetes and associated disorders
- Liver Disease and Transplantation
- Infectious Diseases and Tuberculosis
- Lung Cancer Treatments and Mutations
- COVID-19 Impact on Reproduction
- Osteomyelitis and Bone Disorders Research
- Pediatric Hepatobiliary Diseases and Treatments
- Transplantation: Methods and Outcomes
- Renal cell carcinoma treatment
Medizinische Hochschule Hannover
2018-2024
ERN GUARD-Heart
2022
ERN RARE-LIVER
2022
Goethe University Frankfurt
2000
Personalized immunosuppression (IS) promises to improve the balance of necessary control alloreactivity and dose-dependent adverse effects long-term IS such as kidney insufficiency, infections, malignancies. The majority liver transplantation (LT) recipients exhibit graft injuries (graft inflammation and/or fibrosis) that are not eligible for an reduction according current Banff criteria, even when enzymes normal or only marginally elevated. This cross-sectional study evaluated noninvasive...
Mortality due to COVID-19 is not increased in immunosuppressed individuals after liver transplantation (OLT) compared without immunosuppression. Data on long-term protective immunity against SARS-CoV-2 convalescents, limited. We prospectively measured immune responses by quantifying antibodies 4 different antigens (spike protein 1 and 2, receptor binding domain, nucleocapsid) T cell IFN-γ ELISPOT (membrane, nucleocapsid, spike 2) 24 OLT convalescents with immunosuppressive therapy...
Abstract Background and aim The distinction of drug-induced liver injury (DILI), autoimmune-like hepatitis (DI-ALH) autoimmune (AIH) can be challenging due to overlapping clinical characteristics. Recently, polyreactive immunoglobulin G (pIgG) was identified as a novel biomarker with higher accuracy for the diagnose AIH than conventional autoantibodies. This retrospective multicenter study aimed evaluate diagnostic pIgG distinguish between AIH, DI-ALH DILI thus identify patients in need...
<ns3:p><ns3:bold>Background:</ns3:bold> Autoimmune hepatitis (AIH) is a rare liver disease predominantly affecting women. Data on AIH in African patients rare. A previous study from the UK reported an unusual form of Somalian patients.</ns3:p><ns3:p> <ns3:bold>Methods:</ns3:bold> To examine whether this can also be found Germany, we screened database major tertiary transplantation center.</ns3:p><ns3:p> <ns3:bold>Results and conclusions:</ns3:bold> Among 17 presenting to our hospital between...