Mathew Muturi

ORCID: 0000-0003-2110-8099
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About
Contact & Profiles
Research Areas
  • Animal Disease Management and Epidemiology
  • Zoonotic diseases and public health
  • Viral Infections and Vectors
  • Viral Infections and Outbreaks Research
  • Rabies epidemiology and control
  • Virology and Viral Diseases
  • Yersinia bacterium, plague, ectoparasites research
  • Vector-Borne Animal Diseases
  • Brucella: diagnosis, epidemiology, treatment
  • Animal Diversity and Health Studies
  • Microbial infections and disease research
  • Poxvirus research and outbreaks
  • Mosquito-borne diseases and control
  • Vector-borne infectious diseases
  • Influenza Virus Research Studies
  • Viral gastroenteritis research and epidemiology
  • Bacillus and Francisella bacterial research
  • SARS-CoV-2 and COVID-19 Research
  • Energy and Environment Impacts
  • Psychological Treatments and Assessments
  • Socioeconomic Development in MENA
  • Food Safety and Hygiene
  • Indoor Air Quality and Microbial Exposure
  • Business Strategies and Management Research
  • African Education and Politics

Kenya Wildlife Service
2018-2025

Ministry of Agriculture Livestock and Fisheries
2018-2025

Ministry of Health
2017-2025

International Livestock Research Institute
2020-2025

Freie Universität Berlin
2022-2025

Smithsonian Conservation Biology Institute
2025

University of Nairobi
2024

Government of Kenya
2022-2023

Ross University School of Veterinary Medicine
2018-2019

Swiss Centre for Scientific Research
2019

More than 75% of emerging infectious diseases are zoonotic in origin and a transdisciplinary, multi-sectoral One Health approach is key strategy for their effective prevention control. In 2004, US Centers Disease Control Prevention office Kenya (CDC Kenya) established the Global Detection Division which one core component was to support, with other partners, public health science. After catalytic events such as global expansion highly pathogenic H5N1 2006 East African multi-country outbreaks...

10.1186/s12889-019-6772-7 article EN cc-by BMC Public Health 2019-05-01

Epidemiologic data indicate a global distribution of anthrax outbreaks associated with certain ecosystems that promote survival and viability Bacillus anthracis spores. Here, we characterized three involving humans, livestock, wildlife occurred in the same locality Kenya between 2014 2017. Clinical epidemiologic on were collected using active case finding review human, health records. Information temporal spatial prior area was participatory epidemiology. The 2014–2017 Nakuru West subcounty...

10.4269/ajtmh.18-0224 article EN cc-by American Journal of Tropical Medicine and Hygiene 2018-08-14

On the last week of May 2018, a community-based syndromic surveillance system detected mass abortions and deaths young livestock in northeastern Kenya. Two weeks later, Rift Valley fever (RVF) was confirmed humans presenting with febrile illness hemorrhagic syndrome same region. A joint animal human response team carried out an investigation to characterize outbreak identify drivers disease transmission. Here, we describe findings. total 106 cases were identified months June 2018: 92% (98)...

10.4269/ajtmh.20-0387 article EN American Journal of Tropical Medicine and Hygiene 2020-08-04

Nigeria, with a population of over 190 million people, is rated among the 10 countries highest burden infectious and zoonotic diseases globally. In there exist sub-optimal surveillance system to monitor track priority zoonoses. We therefore conducted prioritization for first time in Nigeria guide prevention control efforts. Towards this, two-day in-country consultative meeting involving experts from human, animal, environmental health backgrounds prioritized using modified semi-quantitative...

10.1016/j.onehlt.2021.100257 article EN cc-by-nc-nd One Health 2021-04-28

As countries with endemic canine rabies progress towards elimination by 2030, it will become necessary to employ techniques help plan, monitor, and confirm elimination. Sequencing can provide critical information inform control vaccination strategies identifying genetically distinct virus variants that may have different host reservoir species or geographic distributions. However, many testing laboratories lack the resources expertise for sequencing, especially in remote rural areas where...

10.3390/v12111255 article EN cc-by Viruses 2020-11-04

<ns4:p><ns4:bold>Background</ns4:bold>: Rabies causes an estimated 59,000 human deaths annually. In Kenya, rabies was first reported in a dog 1912, with the case 1928. Here we examine retrospective data Kenya for period 1912 – 2017 and describe spatial temporal patterns of occurrence country. Additionally, detail Kenya’s strategy elimination dog-mediated by 2030.</ns4:p><ns4:p> <ns4:bold>Methods</ns4:bold>: Data on submitted samples confirmed cases humans, domestic animals wildlife were...

10.12688/aasopenres.12872.2 preprint EN cc-by AAS Open Research 2019-02-15

The majority of Kenya’s &gt; 3 million camels have antibodies against Middle East respiratory syndrome coronavirus (MERS-CoV), although human infection in Africa is rare. We enrolled 243 aged 0–24 months from 33 homesteads Northern Kenya and followed them between April 2018 to March 2020. collected tested camel nasal swabs for MERS-CoV RNA by RT-PCR virus isolation whole genome sequencing positive samples. also documented illnesses (respiratory or other) among the camels. Human handlers were...

10.3390/v14081743 article EN cc-by Viruses 2022-08-09

African buffalo (Syncerus caffer) is a significant reservoir host for many zoonotic and parasitic infections in Africa. These include range of viruses pathogenic bacteria, such as tick-borne rickettsial organisms. Despite the considerations mammalian blood sterile environment, microbiome sequencing could become crucial agnostic biosurveillance. This study investigated clinically healthy wild buffaloes Kenya to determine its applicability testing bacteria apparently animals. Whole serum...

10.1186/s42523-024-00374-9 article EN cc-by-nc-nd Animal Microbiome 2025-01-12

Kenya launched a Rabies Elimination Strategy in 2014, aiming to end human rabies deaths by 2030. In March 2022, Lamu County reported increased cases of dog bites and suspected the Ministry Health (MoH). We aimed establish extent outbreak humans animals determine challenges achieving elimination extracted bite reports from Information System (KHIS), national surveillance database system, reviewed medical records at health facilities for 2020 2022. obtained information about animal illnesses...

10.1186/s42522-024-00129-1 article EN cc-by-nc-nd One Health Outlook 2025-02-09

Background of the study: Stress is a natural response to daily challenges, and while small amounts can be manageable, excessive stress harms health. Men women differ in their cognitive function, tolerance, emotional reactions stress. Research by Dr. Judith Mohring suggests often face more workload despite similar pressures. Relaxation techniques, like Benson’s relaxation therapy, effectively induce calming “relaxation response.” Aim: The study was aimed evaluate effectiveness therapy...

10.36948/ijfmr.2025.v07i02.39134 article EN cc-by-sa International Journal For Multidisciplinary Research 2025-03-17

Coxiella burnetii, the causative agent of Q fever, is an emerging pathogen that has potential to cause severe chronic infections in animals and humans worldwide. The detrimental impact on public health projected be higher low- middle-income countries given their lower capacity sustain effective surveillance response measures. We implemented a national serosurvey cattle Kenya map spatial distribution pathogen. study used serum samples were collected from randomly selected different...

10.1038/s41598-025-94154-3 article EN cc-by-nc-nd Scientific Reports 2025-03-21

Background To improve early detection of emerging infectious diseases in sub-Saharan Africa (SSA), many them zoonotic, numerous electronic animal disease-reporting systems have been piloted but not implemented because cost, lack user friendliness, and data insecurity. In Kenya, we developed rolled out an open-source mobile phone-based domestic wild disease reporting system collected over two years to investigate its robustness ability track trends. Methods The Kenya Animal Biosurveillance...

10.1371/journal.pone.0244119 article EN public-domain PLoS ONE 2021-09-03

Camels are increasingly becoming the livestock of choice for pastoralists reeling from effects climate change in semi-arid and arid parts Kenya. As population camels rises, better understanding their role epidemiology zoonotic diseases Kenya is a public health priority. Rift Valley fever (RVF), brucellosis Q three top priority country but involvement transmission dynamics these poorly understood. We analyzed 120 camel serum samples northern to establish seropositivity rates pathogens...

10.1371/journal.pntd.0009275 article EN cc-by PLoS neglected tropical diseases 2021-03-26

Abstract Nearly a century after the first reports of Rift Valley fever (RVF) were documented in Kenya, questions on transmission dynamics disease remain. Specifically, data viral maintenance quiescent years between epidemics is limited. We implemented cross-sectional study northern Kenya to determine seroprevalence, risk factors, and ecological predictors RVF humans livestock during an interepidemic period. Six hundred seventy-six human 1,864 samples screened for anti-RVF Immunoglobulin G...

10.1038/s41598-023-42596-y article EN cc-by Scientific Reports 2023-09-15

<title>Abstract</title> <italic>Coxiella burnetii</italic> is the causative agent of Q fever, a zoonotic infection that poses serious threats to both animal and human health, particularly in Global South. This bacterium primarily infects livestock such as cattle, sheep goats can be transmitted humans through inhalation contaminated aerosols or contact with infected products like milk urine. The disease leads losses febrile illnesses humans. A longitudinal study was conducted collect blood...

10.21203/rs.3.rs-6205861/v1 preprint EN cc-by Research Square (Research Square) 2025-03-28

Prompt provision of post-exposure-prophylaxis (PEP) including vaccines and rabies immunoglobulin (RIG) to persons bitten by suspect rabid dogs is a key strategy eliminating human deaths from dog-mediated in Kenya 2030. We assessed the availability, forecasting supply chain logistics for PEP Kenya, compared with system used expanded program immunization (routine vaccines). Semi-structured questionnaires capturing data on forecasting, procurement, distribution, cold storage, monitoring...

10.1016/j.vaccine.2019.05.035 article EN cc-by Vaccine 2019-07-17

The seroprevalence of brucellosis among nomadic pastoralists and their livestock in arid lands is reported to be over10-fold higher than non-pastoralists farmers Kenya. Here, we compared the mixed farming with knowledge disease high-risk practices associated infection.Across-sectional study was conducted two counties - Kiambu County where primarily practice smallholder production crop farming, Marsabit pastoral production. Stratified random sampling applied, which sublocations were initially...

10.1186/s12889-020-8362-0 article EN cc-by BMC Public Health 2020-02-24

Background Brucellosis occurs globally with highly variable incidence in humans from very low North America and Western Europe to high the Middle East Asia. There are few data Sub-Saharan Africa. This study estimated of human brucellosis a pastoralist community Kenya. Methods Between February 2015 January 2016, we enrolled persons living randomly selected households Kajiado County. Free health care was offered at three facilities area. Those who met clinical case definition completed...

10.1371/journal.pntd.0009049 article EN public-domain PLoS neglected tropical diseases 2021-02-01

Background An estimated 59,000 people die from rabies annually, with 99% of those deaths attributable to bites domestic dogs (Canis lupus familiaris). This preventable Neglected Tropical Disease has a large impact across continental Africa, especially for rural populations living in close contact livestock and wildlife. Mass vaccinations are effective at eliminating but require amounts resources, planning, political will implement. Grassroots campaigns provide an alternative method...

10.1371/journal.pntd.0008260 article EN public-domain PLoS neglected tropical diseases 2020-07-02

Developing disease risk maps for priority endemic and episodic diseases is becoming increasingly important more effective management, particularly in resource limited countries. For easily diagnosed such as anthrax, using historical data to identify hotspots start define ecological factors of its occurrence a plausible approach. Using 666 livestock anthrax events reported Kenya over 60 years (1957-2017), we determined the temporal spatial patterns step towards identifying characterizing region.

10.1186/s12879-021-05871-9 article EN cc-by BMC Infectious Diseases 2021-02-18
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