A5060847164- Fungal Biology and Applications
- Probiotics and Fermented Foods
- Antifungal resistance and susceptibility
- Essential Oils and Antimicrobial Activity
- Curcumin's Biomedical Applications
- Nail Diseases and Treatments
- Veterinary medicine and infectious diseases
- Natural Products and Biological Research
- Fungal and yeast genetics research
- Yersinia bacterium, plague, ectoparasites research
- Cardiac Fibrosis and Remodeling
- Genomics, phytochemicals, and oxidative stress
- Digestive system and related health
- Inflammatory mediators and NSAID effects
- Bacterial biofilms and quorum sensing
- Microbial infections and disease research
- Bird parasitology and diseases
- Polymer Surface Interaction Studies
- Tracheal and airway disorders
- Livestock and Poultry Management
- Liver Diseases and Immunity
- Analytical Methods in Pharmaceuticals
- Animal health and immunology
- Chromatography in Natural Products
- Food Quality and Safety Studies
Peoples' Friendship University of Russia
2013-2024
Russian New University
2023
Mastitis is one of the most important diseases cows and expensive pathology for dairy industry. Therefore, this study was conducted to explore role microorganisms isolated from with mastitis in formation biofilms under conditions farm biogeocenosis Moscow region.Periodic visits 12 farms region were microbial profile udder mastitis. During visits, 103 milk samples sick animals collected examined. Through microbiological analyses, 486 cultures identified, which are assigned 11 genera. caused...
Candida albicans was the first eukaryotic microorganism to exhibit quorum-sensing through secretion of sesquiterpene E, farnesol. This molecule is generated by dephosphorylation farnesyl pyrophosphate in mevalonate biosynthetic pathway mammalian and yeast cells. Exogenous farnesol inhibits yeast-to-hyphal formation a concentration- time-dependent manner at earliest stage hyphal development. Much research has been devoted studying role as an inhibitor morphogenesis; however, little published...
Expandable metallic stent placement is often the only way to treat airway obstructions. Such treatment with an uncoated causes granulation proliferation and subsequent restenosis, resulting in procedure’s adverse complications. Systemic administration of steroids drugs high dosages slows down tissue overgrowth but leads long-term side effects. Drug-eluting coatings have been used widely cardiology for many years suppress local reduce organism’s systemic load. Still, so far, there are no...
Clinical strains of microorganisms, including pathogenic yeast-like fungi (YLF), are resistant to currently used antifungal agents. Thus, it is relevant study the combinations existing antimicrobial drugs and a medicinal extract plant origin (farnesol). In previous studies, farnesol showed relatively strong anti-biofilm effect against Candida albicans. This aimed determine how much resistance profile non-biofilm microorganisms can change. Six clinical isolates C. albicans one reference...
Background: Dilated cardiomyopathy is common in dogs. This form of the main cause death due to heart disease Death can occur suddenly clinically normal animals as a result progression congestive failure (CHF). The pathogenesis syndrome dogs with dilated involves activation neurohumoral system and immune-mediated inflammation, which leads further condition. Heart caused by progressive loss cardiomyocytes, apoptosis, remodeling left ventricle, systolic diastolic dysfunction, arrhythmias,...
Nanotechnology has gained significant interest in various applications, including sensors and therapeutic agents for targeted disease sites. Several pathological consequences, cancer, Alzheimer’s disease, autoimmune diseases, many others, are mostly driven by inflammation Nrf2, its negative regulator, the E3 ligase adaptor Kelch-like ECH-associated protein 1 (Keap1), plays a crucial role maintaining redox status, expression of antioxidant genes, inflammatory response. Interestingly, tuning...
Chronic otitis externa of dogs is a significant problem due to the prevalence and complexity treatment such animals. There evidence that in 60-80% cases infectious diseases microorganisms located biofilm phenotype play main role. Microorganisms have number advantages, most which considered be increased resistance various external factors. Among them, special place occupied by antibiotics. In recent decades, research has been conducted at an increasing scale on role infections pathologies...
Rainbow trout fingerlings were fed, in triplicate, diets supplemented with 0 (CTL), 50 (50 TM), 100 (100 200 (200 400 (400 TM) and 800 (800 mg/kg of thymol, followed by 48 h thermal stress. Growth performance humoral immunological parameters showed no significant responses to dietary thymol concentrations. Fish fed 50-400 had significantly higher survival after heat Plasma cortisol, glucose, hepatic glutathione peroxidase, reductase erythrocyte catalase increased stress, whereas total plasma...
Introduction. Dihydroquercetin is a flavonoid from the group of flavanonols with wide spectrum pharmacological activity. Its positive therapeutic profile was established for chronic venous insufficiency, obstructive pulmonary disease and bronchial asthma, prevention stroke. use leads to an improvement in course atherosclerosis Alzheimer's disease. In addition, it characterized by radio-protective, antidote, anti-inflammatory, anti-allergic, reparative, hepatoprotective effects. Currently,...
The therapeutic potential of Angelica ternata extract was tested against biofilm-associated fungi Candida albicans. Such an with a 1.896 ± 0.071% per 1 mL rutin content flavonoids can reliably suppress the formation biofilms pathogenic yeast-like up to 76.6%. herbal medicine has significant effect on initiation, adhesion, and development biofilms. If is added developed biofilm, it matrix. As result, “glue” between cells washed out they are more easily away from well microplate which...
Difficulties of the earliest stages' detection erythrocytes' microrheological abnormalities' development at hypertension are connected with falling out clinicians' field view persons first signs this pathology. It dictates necessity experimental investigations' fulfillment on laboratory animals just developed in them. 87 healthy male-rats Vistar line age 2,5-3 months were taken into investigation. 29 them had experienced no impacts and composed control group. 58 rats by prescribing...
Acute bacterial cholangiohepatitis of cats is a common disease associated with the inflammation bile ducts and liver parenchyma, characterized by development pronounced hepatodepressive syndrome (hypoalbuminemia), cytolysis (increase in serum activity alanine asparagine transaminase), cholestasis concentration bilirubin, cholesterol, alkaline phosphatase gamma-glutamyltranspeptidase), intoxication, dehydration, mesenchymal-inflammatory pain syndromes. The aim research was to study...
Intercorrelative relationships between various clinical and laboratory parameters in dogs with acute gastroenteritis were studied. In alimentary (n = 31), pain rating scale score significantly (p 0.05) correlated pulse rate (r 0.58), respiratory 0.50), hematocrit 0.47), ESR 0.72), number of erythrocytes 0.50) leukocytes 0.77), concentration albumins -0.52), globulins 0.59), 1-globulins 0.49), 2-globulins 0.42), -globulins -0.36), C-reactive protein 0.82), serum activity ALT 0.70), AST 0.39),...
The effect of dental gel with astaxanthin and polyprenol on the detection toxicity local irritant laboratory animals was evaluated. inflammatory reaction, wound healing effect, hematological biochemical parameters were studied when using a polyprenol. When conducting study animals, showed absence effect. antioxidant properties, as well effects animals.
The article describes the clinical and pharmacological effectiveness of a new method combined use peptide drugs to reduce side effects non-steroidal anti-inflammatory on mucous membrane gastrointestinal tract. most effective is observed in cases gastric pathology (gastritis various etiologies) due difficulty replacing from NSAID group with any others during pharmacocorrection lameness horses. A decrease hepatotoxic effect was found, which manifested by AST ALT, level haptoglobin 12,4 %, 2nd...
РезюмеАктуальность: Ар-турмерон один из основных компонентов эфирного масла корневищ Curcuma longa L. Он обусловливает специфичность состава C
Background and Aim: Fungal infections are a growing problem for both humans animals due to the emergence of pathogenic strains resistant modern antifungal treatments. To evaluate efficacy new drugs, it is essential develop animal models that demonstrate typical responses infection (pathogenesis clinical course) treatment, including adverse effects. In this study, we established rabbit otitis model by an aggressive multidrug-resistant strain from dogs, Malassezia pachydermatis C23, with no...
The article describes a new method of combined use medicines in order to reduce the side effect nonsteroidal anti-inflammatory drugs on mucous membrane gastrointestinal tract. most effective is observed gastric pathology - gastritis, various etiologies, due difficulty replacing from NSAID group with any other. A decrease hepatotoxic was established, which manifested by AsAT 1,32 and 1,08 times groups 1 2, respectively, AlAT 1,66 times, respectively; an increase level total protein 6,93 %...