A5011774845- Genetics, Bioinformatics, and Biomedical Research
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Genomics and Rare Diseases
- Gene expression and cancer classification
- Liver Disease Diagnosis and Treatment
- Genomics and Phylogenetic Studies
- Biomedical Text Mining and Ontologies
- Antimicrobial Resistance in Staphylococcus
- Bioinformatics and Genomic Networks
- MicroRNA in disease regulation
- SARS-CoV-2 and COVID-19 Research
- Vitamin D Research Studies
- Essential Oils and Antimicrobial Activity
- Pancreatitis Pathology and Treatment
- Cancer Mechanisms and Therapy
- Microbial Metabolites in Food Biotechnology
- Hepatocellular Carcinoma Treatment and Prognosis
- Circular RNAs in diseases
- Extracellular vesicles in disease
- Probiotics and Fermented Foods
- Occupational and environmental lung diseases
- Pancreatic function and diabetes
- Obesity, Physical Activity, Diet
- Telomeres, Telomerase, and Senescence
University of Tabuk
2022-2025
University of Khartoum
2015-2025
Royal Marsden NHS Foundation Trust
2024
Royal Marsden Hospital
2024
Aswan University
2021
National Water Research Center
2017-2020
The Future University
2017
Zagazig University
2014-2015
Research Institute for Tropical Medicine
2015
Center for Genomic Science
2014
The application of genomics technologies to medicine and biomedical research is increasing in popularity, made possible by new high-throughput genotyping sequencing improved data analysis capabilities. Some the greatest genetic diversity among humans, animals, plants, microbiota occurs Africa, yet genomic outputs from continent are limited. Human Heredity Health Africa (H3Africa) initiative was established drive development for human health through recognition critical role bioinformatics...
Africa is not unique in its need for basic bioinformatics training individuals from a diverse range of academic backgrounds. However, particular logistical challenges Africa, most notably access to expertise and internet stability, must be addressed order meet this on the continent. H3ABioNet (www.h3abionet.org), Pan African Bioinformatics Network H3Africa, has therefore developed an innovative, free-of-charge "Introduction Bioinformatics" course, taking these into account as part...
The discipline of bioinformatics has developed rapidly since the complete sequencing first genomes in 1990s. development many high-throughput techniques during last decades ensured that grown into a overlaps with, and is required for, modern practice virtually every field life sciences. This placed scientific premium on availability skilled bioinformaticians, qualification extremely scarce African continent. reasons for this are numerous, although absence bioinformatician at academic...
Itraconazole (ITZ) is a triazole antifungal agent characterized by broad-spectrum activity against fungal infections. The main drawback of ITZ, when applied topically, the low skin permeability due to stratum corneum, outermost layer skin, which represents barrier for drug penetration. Therefore, this study aimed prepare itraconazole as transferosomes (ITZ-TFS) overcome function skin. ITZ-TFSs were prepared thin lipid film hydration technique using different surfactants, sodium lauryl...
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer associated death globally. Serum micro RNAs are full potential as noninvasive biomarkers. Here, we aim to assess performance serum MicroRNA-155 and MicroRNA-665 diagnostic biomarker for HCC comparing AFP.Serum samples were collected from 200 subjects (40 healthy control, 80 chronic hepatitis C patients with cirrhosis without (LC) currently infected by infection didn't start treatment). The include alcoholic liver disease,...
ABSTRACT Macrorestriction analysis of SmaI-digested chromosomal DNA, using pulsed field gel electrophoresis (PFGE) was performed to type and estimate genetic relationships among 288 Staphylococcus aureus isolates recovered from 58 Eastern Canadian dairy herds. In addition, a subset the collection phage typed evaluated for sensitivity 10 antimicrobial compounds. Of recovered, 29 distinct PFGE types were identified. Based on estimates relationships, assigned six lineage groups, designated A...
Introduction: Betanin (C₂₄H₂₆N₂O₁₃) is safe to use as food additives approved by the FDA with anti-inflammatory and anticancer effects in many types of cancer cell lines. The current experiment was designed test chemotherapeutic effect combination betanin standard agent, capecitabine, against chemically induced colon mice. Methods: Bioinformatic approach get information about possible mechanisms through which drugs may control development. Five groups mice were assigned as, (i) saline, (ii)...
Abstract Ulcerative colitis (UC) is an inflammatory condition of the intestine, resulting from increase in oxidative stress and pro-inflammatory mediators. In this study, extract endophytic bacterium Rhizobium aegyptiacum was prepared for first time using liquid chromatography-mass spectrometry (LC-MS). addition, also time, protective potential R. revealed vivo rat model UC. The animals were grouped into four categories: normal control (group I), II), acetic acid (AA)-induced UC III),...
Background: Fluoroquinolones (FQs) are among the most popular antimicrobials that highly effective against various infections. Although FQs frequently used and generally tolerated, there issues with their safety. This study assessed rate, severity, seriousness, outcomes, types of adverse drug reactions (ADRs) in reports submitted to a regional spontaneous ADR database. Methods: was retrospective cross-sectional observational involving all patients reported ADRs related or other antibiotics...
Background: Antimicrobial resistance is spreading all over the world and at same time rate of discovery antimicrobials in general antibiotics particular diminished. Historically currently many are discovered isolated from soil bacteria other natural sources. In this project our aim to search for antibiotic producing samples. Methods: Soil samples different locations King Salaman Bin Abdulaziz Royal Reserve were collected. cultured Actinomyces special medium incubated 35 °C 4 days. Isolates...
Toxoplasma gondii, a protozoan parasite found in water sources, causes toxoplasmosis, with no current protocols for inactivating its oocysts water. Staphylococcus aureus, significant bacterial pathogen, is known causing various illnesses, including skin infections and biofilm-related diseases. This study investigated the antibacterial antiparasitic properties of Ipomoea palmata leaf extract, rich phenolics, against T. gondii tachyzoites S. aureus. I. extract significantly reduced count...
Students face more challenging conditions as they move forward with their education. As a result of these negative circumstances are vulnerable to mental disorders like anxiety and depression. Thus, the study's goal was determine symptoms depression among King Khalid University students in Saudi Arabia's southern region. A descriptive online institution-based cross-sectional survey design conducted for period 3 months from 20.12.2023 29.02.2024 assess university students. This study utilized...
Background/Objectives: Gouty arthritis (GA) is a chronic inflammatory condition characterized by hyperuricemia and NLRP3 inflammasome activation, leading to joint damage systemic inflammation. Although allopurinol (ALP), xanthine oxidase inhibitor, effectively lowers serum urate levels, it has limited anti-inflammatory effects. This study investigated whether combining disulfiram (DSF), known with ALP enhances therapeutic outcomes in rat model of gout. Methods: Thirty male Albino Wistar rats...