A5101647585- Male Breast Health Studies
- AI in cancer detection
- Glioma Diagnosis and Treatment
- BRCA gene mutations in cancer
- MicroRNA in disease regulation
- Cancer, Lipids, and Metabolism
- Radiomics and Machine Learning in Medical Imaging
- Multiple and Secondary Primary Cancers
- Brain Metastases and Treatment
- Ocular Surface and Contact Lens
- Liver Disease Diagnosis and Treatment
- Craniofacial Disorders and Treatments
- Chronic Myeloid Leukemia Treatments
- Acupuncture Treatment Research Studies
- Circular RNAs in diseases
- Flavonoids in Medical Research
- Global Cancer Incidence and Screening
- Natural product bioactivities and synthesis
- Gastric Cancer Management and Outcomes
- Breast Cancer Treatment Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Autoimmune Bullous Skin Diseases
- Health and Wellbeing Research
- Lung Cancer Diagnosis and Treatment
- Cancer-related molecular mechanisms research
Fudan University Shanghai Cancer Center
2011-2024
Cangzhou Central Hospital
2024
Zhujiang Hospital
2023
Southern Medical University
2023
Nanjing University of Chinese Medicine
2022
Shanghai Medical College of Fudan University
2021-2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2021
First Affiliated Hospital Zhejiang University
2021
Creative Commons
2019
Yan'an University
2016-2019
Over the recent years, machine learning methods have been increasingly explored in cancer prognosis because of appearance improved algorithms. These algorithms can use censored data for modeling, such as support vector machines survival analysis and random forest (RSF). However, it is still debated whether traditional (Cox proportional hazard regression) or learning-based prognostic models better predictive performance.This study aimed to compare performance breast prediction based on Cox...
Micro RNAs play important roles during mammalian spermatogenesis, but the function(s) of specific miRNAs remain largely unknown. Here, we report that miR‐100 is predominantly expressed in undifferentiated murine spermatogonia, including spermatogonial stem cells (SSCs). We utilized a miRNA mimic and inhibitor to knock down overexpress cultured SSCs, respectively, finding promotes proliferation SSCs vitro. Furthermore, signals promoting SSC maintenance induced, whereas retinoic acid...
Background: Previous studies found that the long-term survival of male breast cancer patients differed from those female patients, however, conclusions were contradictory. We conducted study to examine sex disparity in by carefully controlling demographic and clinical factors using data Shanghai Cancer Registry (SCR). Methods: Every patient was matched with four diagnosis year, age, stage, histology. used Kaplan-Meier estimates calculate cumulative observed overall (OS) cancer-specific (CSS)...
To explore the effect of electroacupuncture on endometrial receptivity and pregnancy outcomes in vitro fertilization embryo transfer (IVF-ET) patients with diminished ovarian reserve (DOR).Sixty-eight DOR undertaken IVF-ET were randomized into an observation group (34 cases, 2 cases dropped off) a control 1 case off). In group, preparation was performed according to routine protocol. base treatment as acupuncture applied Geshu (BL 17), Shenshu 23), Mingmen (GV 4), Shiqizhui (EX-B 8), Ciliao...
Cerebral radiation necrosis (RN), a complication of Gamma Knife radiosurgery, is difficult to treat, although bevacizumab seems be effective. However, clinical data pertaining treatment for RN are scarce, and its high price problematic. This study explored the effectiveness low-dose caused by Knife. We retrospectively analyzed 22 patients who suffered cerebral post-Gamma Knife, received because poor efficacy glucocorticoids. Low-dose (3 mg/kg) was administered two cycles at 2-week intervals....
Objective To investigate the effect, right timing, and mechanism of accordion technique on bone regeneration in rat distraction osteogenesis model. Methods Fifty-four 12-week-old male Sprague Dawley rats underwent tibial procedure. After a 5-day latency, was performed for 7 days followed by 6-week consolidation. All animals were randomly divided into 4 groups based different periods maneuvers consolidation phase: control group ( n=18) with no manipulation, three experimental including...
Severe cutaneous adverse reactions (SCAR) to drugs are a crucial public health issue and the use of systemic corticosteroids in SCAR has been controversial.To analyze clinical features, causative drugs, treatment, outcomes, prognostic factors case-series 173 patients, add more information debate using management.A retrospective study patients diagnosed with drug reaction eosinophilia symptoms (DRESS), Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) or acute generalized...
The objective of this study was to prepare doxorubicin-loaded EGF modified PEG-nanoparticles and evaluate its targeting capability therapeutic effects with EGFR-expressing hepatocellular carcinoma cells. morphology, particle size distribution, doxorubicin content the nanoparticles were measured, drug loading encapsulation efficiency calculated. prepared regular circular, good dispersibility, no adhesion, average (136.7±9.3) nm. (76.67±8.63)%, (3.86±0.55)%; release rate 100% for 12 h,...
Previous studies have reported that physical therapy (PT) can be used for the treatment of chronic obstructive pulmonary disease (COPD). However, its effectiveness is still inconclusive. This systematic review will aim to assess and safety patients with COPD.
Colorectal cancer is a malignancy with high mortality. Huangqin Tea(HQT) can exert potential preventive and therapeutic effects on colorectal cancer. Flavonoids are the main compounds in HQT, but pharmacodynamic material basis mechanism unclear. Network pharmacology molecular docking were used to predict analyze targets signaling pathways of HQT prevention treatment The active components flavonoids searched screened out by literature review FAFDrugs4. related predicted SwissTargetPrediction,...
Objective To compare the clinical outcomes of gefitinib and erlotinib treating non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutation in either exon 19 or 21. Methods A total 242 patients diagnosed as NSCLC EGFR 21 from May 2013 to December 2014 our hospital were chosen this study. According age, sex, smoking history, eastern cooperative oncology group performance status types mutation, all matched 121 pairs, randomly divided into A B. Patients...
Tamoxifen has shown definitive effect when used as the adjuvant hormonal treatment in women with estrogen-receptor-positive breast cancer. However, long-term use of can induce fatty liver disease. It been proposed that tamoxifen may act throught mechanisms such inducing triacylglycerol accumulation mitochondria, abnormal acid oxidation, and antagonizing actions estrogen on hepatic lipid metabolism. Therefore, it is necessary to monitor profile function, conduct regular ultrasonography CT...
Objective The aim of the study was to explore difference between expression CDg7 in peripheral blood and bone marrow on acute myeloid leukemia (AML n=30). Methods A flow cytometric quantitative analysis levels for CD87 performed fresh blast cells from patients with leukaemia using CD87, monoclonal antibodies. Analysis matched t -test. Results values 14 M5 cases are 9.47 %～80.32 %, 11.49 %～87.46 % blood. 8 M4 14.27 %～46.28 %,and 14.79 %～47.19 6 M2 4.67 %～34.26 8.96 %～39.78 CDs, 2 MI 3.56...
Abstract Purpose: To examine the differences in long-term survival between male and matched female breast cancer cases based on data from Shanghai Cancer Registry (SCR). Methods: Every case was with four according to year of diagnosis, age, tumor stage, histological subtype. Cumulative observed overall (OS) cancer-specific (CSS) rates were calculated using Kaplan-Meier estimates, log-rank tests applied compare cases. Cox proportional-hazards regression models used assess hazard ratios (HR)...
<sec> <title>BACKGROUND</title> Over the recent years, machine learning methods have been increasingly explored in cancer prognosis because of appearance improved algorithms. These algorithms can use censored data for modeling, such as support vector machines survival analysis and random forest (RSF). However, it is still debated whether traditional (Cox proportional hazard regression) or learning-based prognostic models better predictive performance. </sec> <title>OBJECTIVE</title> This...