A5064713714- Cytokine Signaling Pathways and Interactions
- Reproductive Biology and Fertility
- Angiogenesis and VEGF in Cancer
- Cancer, Lipids, and Metabolism
- Immune cells in cancer
- Medicinal Plant Pharmacodynamics Research
- Endoplasmic Reticulum Stress and Disease
- Estrogen and related hormone effects
- Phagocytosis and Immune Regulation
- Genetics, Aging, and Longevity in Model Organisms
- Memory, History, Trauma, Identity
- Cancer Mechanisms and Therapy
- Social and Demographic Issues in Germany
Konkuk University
2023-2024
Daegu University
2017
Abstract Under endoplasmic reticulum ( ER )‐stress conditions, the unfolded protein response UPR ) generates a defense mechanism in mammalian cells. The regulation of signaling is important oocyte maturation, embryo development, and female reproduction pigs. Recent studies have shown that melatonin plays an role as antioxidant to improve pig maturation. However, there no report on ‐stress during vitro maturation IVM porcine oocytes. Therefore, objective this study was investigate...
Abstract Breast cancer is a frequently diagnosed and the leading cause of death among women worldwide. Tumor‐associated macrophages stimulate cytokines chemokines, which induce angiogenesis, metastasis, proliferation, tumor‐infiltrating immune cells. Although interleukin‐32 (IL‐32) has been implicated in development modulation several cancers, its function breast remains elusive. Mutation interleukin‐32θ (IL‐32θ) tissues patients with was detected by Sanger sequencing. RT‐qPCR used to detect...
Many types of cancer are associated with excessive angiogenesis. Anti-angiogenic treatment is an effective strategy for treating solid cancers. This study aimed to demonstrate the inhibitory effects (E)-2-methoxy-4-(3-(4-methoxyphenyl) prop-1-en-1-yl) phenol (MMPP) in VEGFA-induced The results indicated that MMPP effectively suppressed various angiogenic processes, such as cell migration, invasion, tube formation, and sprouting new vessels human umbilical vein endothelial cells (HUVECs)...
The tumor microenvironment (TME) is formed by several immune cells. Notably, tumor-associated macrophages (TAMs) are existed in the TME that induce angiogenesis, metastasis, and proliferation of cancer Recently, a point-mutated variant IL-32θ was discovered breast tissues, which suppressed migration through intracellular pathways. Although relationship between IL-32 has been previously studied, effects on TAMs remain elusive. Recombinant human (rhIL-32θ) generated using an