- Frailty in Older Adults
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Disease Management Strategies
- Nutrition and Health in Aging
- Aging, Health, and Disability
- Geriatric Care and Nursing Homes
- Dementia and Cognitive Impairment Research
- Health disparities and outcomes
- Mental Health Treatment and Access
- Diabetes Management and Education
- Health and Lifestyle Studies
- Healthcare Decision-Making and Restraints
- Extracellular vesicles in disease
- Nutritional Studies and Diet
- Employment and Welfare Studies
- COVID-19 and Mental Health
- Nursing care and research
- Long-Term Effects of COVID-19
- Obesity, Physical Activity, Diet
- Healthcare Systems and Technology
- Neuroinflammation and Neurodegeneration Mechanisms
- Diabetes Management and Research
- Patient Safety and Medication Errors
- Telemedicine and Telehealth Implementation
- Psychopathy, Forensic Psychiatry, Sexual Offending
Biogipuzkoa Health Research Institute
2016-2024
Red de Investigación en Actividades Preventivas y Promoción de la Salud
2022-2024
Research Network (United States)
2020-2024
Osasun Sistemen Ikerketa Institutua
2018-2023
Centro de Investigación Biomédica en Red
2020-2022
Spanish Clinical Research Network
2022
Osakidetza
2016-2020
Diputación Foral de Gipuzkoa
2018
Policlínica Gipuzkoa
2018
University of the Basque Country
2014-2016
The objective of this study was to estimate the incidence and age onset mental disorders diagnosed by gender socioeconomic status (SES) in children, adolescents, young adults up 30 years whole population Basque Country (Spain).All health diagnoses documented Health Service records from 1 January 2003 31 December 2018, were classified into eight clusters: anxiety, attention deficit hyperactivity disorder (ADHD), conduct disorders, depression, psychosis/personality substance use, eating...
The impact of dietary patterns rather than single foods or nutrients on health outcomes is increasingly recognized. This cross-sectional study examines the 527 non-institutionalized functionally independent older people aged ≥70 years from Gipuzkoa (Spain). Sociodemographic characteristics, status, anthropometric measures and data are collected. Multiple correspondence analysis (MCA) cluster performed to identify groups individuals. Frequency selected food items compliance with...
To evaluate the impact in terms of use health services, clinical outcomes, functional status, and patient's satisfaction an integrated care program, CareWell for complex patients with multimorbidity, supported by information communication technology platforms six European regions.Primary data were used follow-up period ranged between 8 12 months.A quasi-experimental study, targeting chronic aged 65 or older, 2 more conditions - one them necessarily being diabetes, congestive heart failure...
Older patients with multimorbidity have complex health and social care needs, associated elevated use of resources. The aim this study is to evaluate the impact CareWell integrated model for older in Basque Country. program multimorbidity, based on coordination between providers, home-based patient empowerment, supported by information communication technology tools. was deployed four healthcare areas control group formed two organizations which had not been regular procedures were applied....
In the last decades extracellular vesicles (EVs) have emerged as key players for intercellular communication. case of inflammation, several studies reported that EV levels are increased in circulation during inflammatory episodes. Based on this, we investigated whether aging results elevated number, a basal proinflammatory status termed "inflammaging" has been described aged individuals. Moreover, also hypothesized frailty and dependence conditions elderly could affect concentration plasma....
Socioeconomic status (SES) and gender play a key role in mental health. The objective of this study was to assess socioeconomic health inequalities adolescents young adults using population-based registry. We conducted lifetime follow-up all residents the Basque Country between 1 30 years old (n = 609,381) as 31 December 2018. Primary care, specialized outpatient, hospital care records were searched for diagnoses. SES assessed based on household income. estimated disaggregated prevalence...
Abstract Background Regarding the health care of older populations, WHO recommends shifting from disease-driven attention models towards a personalized, integrated and continuous aimed to maintenance enhancement functional capacities. Impairments in construct intrinsic capacity have been understood as condition frailty or vulnerability. No consensus has yet reached regarding which tools are most suitable for screening this kind patients primary settings. Tools based on measurement...
Aging is a universal and complex process that affects all tissues cells types, including immune cells, in known as immunosenescence.However, many aspects of immunosenescence are not completely understood, the characteristics nonagenarians centenarians or features implications extracellular vesicles (EVs).In this study, we analyzed blood samples from 51 individuals aged 20-49 70-104 years.We found senescent CD8 accumulate with age, while there partial reduction CD4 centenarians.Moreover,...
Objectives To investigate which were the most relevant sociodemographic and clinical variables associated with COVID-19 severity, uncover how their inter-relations may have affected such severity. Design A retrospective observational study based on electronic health record data. Participants Individuals ≥14 years old a positive PCR or serology test, between 28 February 31 May 2020, belonging to Basque Country (Spain) public system. Institutionalised individuals admitted hospital at home unit...
Due to population ageing and medical advances, people with advanced chronic diseases (ACD) live longer. Such patients are even more likely face either temporary or permanent reduced functional reserve, which typically further increases their healthcare resource use the burden of care on caregiver(s). Accordingly, these caregiver(s) may benefit from integrated supportive provided via digitally supported interventions. This approach maintain improve quality life, increase independence,...
The existing evidence suggests that a complete evaluation of mental health should incorporate both psychopathology and well-being indicators. However, few studies categorize European adolescents into subgroups based on such data. This study used the data symptoms behavioral disorders to explore profiles in Europe.Data collected from (N = 3767; mean age 12.4 [SD 0.9]) five countries supplied information their (personal resilience, school quality life, well-being) disorder (anxiety,...
La obesidad en la población pediátrica y su efecto génesis de las enfermedades metabólicas constituye un gran problema salud pública. Uno los objetivos del estudio ámbito europeo PRE-STARt Euskadi es evaluar efectividad programa promoción salud, dirigido a adolescentes con factores riesgo asociados al desarrollo diabetes mellitus tipo 2 (DMT2). Ensayo clínico doble grupo aleatorizado 12 14 años exceso ponderal. El intervención recibió multidisciplinar durante 24 meses, 11 sesiones grupales...
Trained immunity (TRAIM) or the enhanced non-specific immune response after primary stimulation by infection vaccination is a recent but well-recognized concept. To verify its predictions, our objective was to determine effects of two bacterial vaccines, typhoid fever (TFV) and diphtheria-tetanus-pertussis (DTP) on infection, hospitalization death frequencies associated COVID-19 in retrospective study subjects vaccinated not with TFV DTP 4 years prior start pandemia Basque Country (Spain)....
Obesity in the child population and its effect development of metabolic diseases are a public health issue. One aims European Project system, is evaluation effectiveness multidisciplinary promotion program directed at adolescents with risk factors associated type 2 Diabetes Mellitus (T2DM). Randomised clinical trial two groups 12–14 year-old overweight adolescents. The intervention group took part for 24 months. This was based on 11 sessions (8 main 3 additional support ones) their...
Functional performance in older adults is a predictor of survival and other health outcomes its measurement highly recommended primary care settings. frailty are closely related concepts, status associated with the use services. However, there insufficient evidence on utilization services profile according to functional adults. The aim this study was assess relationship between wide range community-dwelling Generalized additive models for location, scale shape were used these complex data...
As mental health in adulthood is related to status during adolescence, school-based interventions have been proposed improve resilience. The objective of this study was build a simulation model representing the natural history disorders childhood, adolescence and youth estimate cost-effectiveness UPRIGHT intervention promoting resilience adolescence.We built discrete event fed with real-world data (cumulative incidence disaggregated into eight clusters) from Basque Health Service database...
<title>Abstract</title> <bold>BACKGROUND: </bold>Accumulating evidence supports the notion that dementia is a multifactorial condition with various risk factors and causes. The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment Disability (FINGER) demonstrated lifestyle interventions could confer cognitive benefits. Inspired by this, GOIZ-ZAINDU (GZ) feasibility study adapted FINGER approach Basque context. Building upon GZ study, CITA GO-ON trial aims enhance expand...