A5000006051- Aquaculture disease management and microbiota
- Invertebrate Immune Response Mechanisms
- Aquaculture Nutrition and Growth
- interferon and immune responses
- Physiological and biochemical adaptations
- Immune Response and Inflammation
- Fish Biology and Ecology Studies
- Identification and Quantification in Food
- Antimicrobial Peptides and Activities
- Genomics and Phylogenetic Studies
- Ichthyology and Marine Biology
- Chemokine receptors and signaling
- Immune Cell Function and Interaction
- Cell death mechanisms and regulation
- MicroRNA in disease regulation
- Cytokine Signaling Pathways and Interactions
- Protease and Inhibitor Mechanisms
- Redox biology and oxidative stress
- Trace Elements in Health
- Animal Virus Infections Studies
- Mosquito-borne diseases and control
- Autophagy in Disease and Therapy
- Complement system in diseases
- Ocean Acidification Effects and Responses
- Marine Bivalve and Aquaculture Studies
Fujian Agriculture and Forestry University
2018-2025
Fujian Institute of Oceanography
2010-2024
Ministry of Natural Resources
2013-2019
Ningbo University
2017-2019
Fujian Fisheries Research Institute
2014-2017
Ministry of Water Resources of the People's Republic of China
2015
Second Institute of Oceanography
2014
The large yellow croaker Larimichthys crocea (L. crocea) is one of the most economically important marine fish in China and East Asian countries. It also exhibits peculiar behavioral physiological characteristics, especially sensitive to various environmental stresses, such as hypoxia air exposure. These traits may render L. a good model for investigating response mechanisms stress. To understand molecular genetic underlying adaptation stress, we sequenced assembled genome using bacterial...
Abstract Background The large yellow croaker ( Pseudosciaena crocea ) is an economically important marine fish in China suffering from severe outbreaks of infectious disease caused by bacteria such as Aeromonas hydrophila A. ), resulting great economic losses. However, the mechanisms involved immune response this to bacterial infection are not fully understood. To understand molecular underlying pathogenic bacteria, we used high-throughput deep sequencing technology investigate transcriptome...
The large yellow croaker (Pseudosciaena crocea) is an economically important marine fish in China. To understand the molecular basis for antiviral defense this species, we used Illumia paired-end sequencing to characterize spleen transcriptome of polyriboinosinic:polyribocytidylic acid [poly(I:C)]-induced croakers. library produced 56,355,728 reads and assembled into 108,237 contigs. As a result, 15,192 unigenes were found from transcriptome. Gene ontology analysis showed that 4,759 genes...
Abstract Larimichthys crocea (large yellow croaker) is a type of perciform fish well known for its peculiar physiological properties and economic value. Here, we constructed an improved version the L. genome assembly, which contained 26,100 protein-coding genes. Twenty-four pseudo-chromosomes were also reconstructed, comprising 90% assembly. This assembly revealed several expansions in gene families associated with olfactory detection, detoxification, innate immunity. Specifically, six...
Hadal environments (depths below 6,000 m) are characterized by extremely high hydrostatic pressures, low temperatures, a scarce food supply, and little light. The evolutionary adaptations that allow vertebrates to survive in this extreme environment poorly understood. Here, we constructed high-quality reference genome for Yap hadal snailfish (YHS), which was captured at depth of ~7,000 m the Trench. final YHS assembly 731.75 Mb, with contig N50 0.75 Mb scaffold 1.26 Mb. We predicted 24,329...
In this study, we applied a comparative proteomic approach to the analysis of differentially expressed proteins in spleens large yellow croaker following treatment with an inactivated trivalent bacterial vaccine. Twenty-four altered were identified by MALDI-TOF or MALDI-TOF-TOF, including immune-related proteins, antioxidant signal transducers, protein biosynthesis and catabolism modulators, carbonic anhydrases. Three Prx family members, namely, I, II, IV, upregulated after vaccine,...
How organisms cope with coldness and high pressure in the hadal zone remains poorly understood. Here, we sequenced assembled genome of sea cucumber Paelopatides sp. Yap quality explored its potential mechanisms for deep-sea adaptation. First, expansion ACOX1 rate-limiting enzyme DHA synthesis pathway, increased content phospholipid bilayer, positive selection EPT1 may maintain cell membrane fluidity. Second, three genes translation initiation factors two ribosomal proteins underwent...
Abstract In mammals, type I IFNs, which commonly contain one or two disulfide bonds, activate the JAK-STAT signaling pathway through binding to common cell surface receptor formed by IFN-α/β (IFNAR)1 and IFNAR2 subunits. Although IFNs are also known be essential for antiviral defense in teleost fish, very little is about mechanisms underlying recognition of fish associated receptors. this study, we demonstrate that a IFN large yellow croaker Larimichthys crocea (LcIFNi), belonging new...
Vaccination is an effective and safe strategy for combating bacterial diseases in fish, but the mechanisms underlying early immune response after vaccination remain to be elucidated. In present study, we used RNA-seq technology perform transcriptome analysis of spleens from large yellow croaker (Larimichthys crocea) induced by inactivated trivalent vaccine (Vibrio parahaemolyticus, Vibrio alginolyticus Aeromonas hydrophila). A total 2,789 or 1,511 differentially expressed genes (DEGs) were...
High-density genetic maps are essential for genome assembly, comparative genomic analysis and fine mapping of complex traits. In this study, 31,191 single nucleotide polymorphisms (SNPs) evenly distributed across the large yellow croaker (Larimichthys crocea) were identified using restriction-site associated DNA sequencing (RAD-seq). Among them, 10,150 high-confidence SNPs assigned to 24 consensus linkage groups (LGs). The total length map was 5451.3 cM with an average distance 0.54 between...
The large yellow croaker (Larimichthys crocea) displays pronounced behavioral changes in response to low oxygen environments, including restlessness, constant floating, and increases respiratory rate tail beat frequency. However, the underlying molecular mechanisms governing these physiological alterations remain unclear. To address this knowledge gap, present study employed transcriptome analysis investigate responses muscle tissue after fish were exposed hypoxic treatment. A total of 4553,...