A5087977066- Traumatic Brain Injury Research
- COVID-19 and healthcare impacts
- Cardiac Arrest and Resuscitation
- Sleep and related disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Infection Control and Ventilation
- RNA regulation and disease
- Technology Use by Older Adults
- Economic and Financial Impacts of Cancer
- Education and Critical Thinking Development
- Resilience and Mental Health
- Lysosomal Storage Disorders Research
- Sleep and Wakefulness Research
- Healthcare cost, quality, practices
- Trauma and Emergency Care Studies
- Biomedical and Engineering Education
- Patient-Provider Communication in Healthcare
- Posttraumatic Stress Disorder Research
- Chemotherapy-related skin toxicity
- Mental Health and Patient Involvement
- Science Education and Pedagogy
- Sleep and Work-Related Fatigue
- Spinal Cord Injury Research
- Studies on Chitinases and Chitosanases
- RNA Research and Splicing
National Human Genome Research Institute
2022-2023
National Institutes of Health
2022-2023
D.Y. Patil University
2023
University of Toronto
2017-2022
Ontario Brain Institute
2017-2022
Guy's and St Thomas' NHS Foundation Trust
2020-2021
Acquired Brain Injury Ireland
2020
University Health Network
2019-2020
Toronto Rehabilitation Institute
2017-2020
<bold>Background:</bold> There is insufficient evidence to support clinical decision-making for cancer patients diagnosed with COVID-19 due the lack of large studies. <bold>Methods:</bold> We used data from a single UK Cancer Center assess demographic/clinical characteristics 156 confirmed diagnosis between 29 February and 12 May 2020. Logistic/Cox proportional hazards models were identify which demographic and/or associated severity/death. <bold>Results:</bold> 128 (82%) presented...
Abstract Background Using an updated dataset with more patients and extended follow-up, we further established cancer patient characteristics associated COVID-19 death. Methods Data on all a positive reverse transcription-polymerase chain reaction swab for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) at Guy’s Cancer Centre King’s College Hospital between 29 February 31 July 2020 was used. Cox proportional hazards regression performed to identify which factors were mortality....
Understanding the genetic mechanisms underlying diseases in ancestrally diverse populations is a critical step towards realization of global application precision medicine. The African and admixed enable mapping complex traits given their greater levels diversity, extensive population substructure, distinct linkage disequilibrium patterns.Here we perform comprehensive genome-wide assessment Parkinson's disease (PD) 197,918 individuals (1,488 cases; 196,430 controls) ancestry, characterizing...
Despite recognizing that women have worse outcomes after traumatic brain injury (TBI), little is known about how gender influences their experiences of this critical injury. Past research has been dominated by androcentrism and quantitative approaches, leaving the lived experience with TBI insufficiently examined. To gain insight into experiences, qualitative study interviewed 19 Canadian mild moderate-to-severe TBIs. Applying a thematic analysis, we discerned three themes: Gender prevails...
Research shows that gender influences men's health-related beliefs and behaviours - including those within the context of traumatic brain injury (TBI) making it a factor should be considered when designing implementing interventions for this population. To incorporate an understanding such gendered in future educational materials men with TBI, as well their caregivers clinicians, qualitative study was informed by social constructionism, aimed to explore how is related post-TBI perceptions...
Caregiving is highly stressful and associated with poor mental physical health. Various technologies, including mobile eHealth apps, have been developed to address caregiver needs. However, there still a paucity of research examining the technology perceptions informal caregivers, especially from perspectives sex, gender, diversity.To gap inform development future caregiving this study aims examine how family caregivers perceive using assist their routines; identify diversity factors that...
Very few studies investigating COVID-19 in cancer patients have included as controls. We aimed to identify factors associated with the risk of testing positive for SARS CoV2 infection a cohort patients. analyzed data from all swabbed between 1st March and 31st July 2020 at Guy’s Cancer Centre. conducted logistic regression analyses which were test. Results: Of 2152 tested COVID-19, 190 (9%) positive. Male sex, black ethnicity, hematological type positively (OR = 1.85, 95%CI:1.37–2.51; OR...
Introduction The initiation and translation of sex-sensitive gender-sensitive research programmes into clinically useful considerations for patients with traumatic brain injury (TBI) have been difficult. Clinical frameworks are currently not specific according to sex gender, despite evidence that these constructs influence the incidence, course outcome TBI. present protocol outlines a strategy programme, supported by Canadian Institutes Health Research (CIHR) Institute Gender Health, which...
Aim This research aimed to gain an understanding of biological sex and social gender phenomena experienced by patients with traumatic brain injury in recovery, understand the educational needs this group.Methods We conducted semi-structured interviews 40 adult (22 men, 18 women) different ages, education levels, ethnicities, diagnoses mild moderate-severe at acute chronic stages post-injury.Results Applying classic content analysis inductive coding, three overarching themes that limited...
Purpose Research shows that patients’ perceptions of themselves and others, in addition to their understanding the concept gender, changes after traumatic brain injury (TBI). Little is known about gendered experiences TBI care delivery. This study aims explore gender through life interactions between adult patients with informal caregivers.Materials Methods Seven mild moderate-severe eight caregivers were interviewed. Transcripts coded analysed according Braun Clarke’s thematic analysis. The...
To evaluate the efficacy of a mobile phone application to facilitate oral hygiene practices in children with ADHD.This was randomized controlled study that included 54 ADHD after obtaining informed parental consent. The were randomly divided into 2 groups; Group 1 (conventional) participants instructed verbally as well demonstrated brushing technique on models. (mobile application) made download and use 'BRUSH DJ' app developed by Ben Underwood. At baseline, index-simplified (OHI-S) [Greene...
Introduction The use of facial recognition technology has diversified the diagnostic toolbelt for clinicians and researchers accurate diagnoses patients with rare challenging disorders. Specific identifiers in patient images can be grouped using artificial intelligence to allow diseases syndromes similar features. Lysosomal storage disorders are rare, some have prominent unique features that may used train accuracy software algorithms. Noteworthy lysosomal (LSDs) include such as brows, wide...
Abstract Background: The Coronavirus disease 2019 (COVID-19) pandemic continues to have a significant impact on the treatment of cancer patients. Understanding clinical course, potential risk factors for severe infection and excess mortality, is essential improve patient outcomes. We previously presented preliminary results from 156 SARS-CoV-2 positive patients Guy’s Cancer Center, which suggested that increased COVID-19 mortality was associated with diagnosis over 2 years, Asian ethnicity...
The main focus of healthcare delivery is to ensure patient safety while practising evidence-based medicine. While doing so the medicolegal professional also utmost importance. We noticed that a large number E-noting entries made for inpatients did not have enough information ascertain accountability entry. This intrigued us look into set standards documentation and then compare them practice generally adopted on ward assess if …
Abstract Background: The COVID-19 pandemic has influenced treatment decisions in cancer patients. There is increasing evidence that not all oncology patients are at increased risk of infection or death. This study aimed to look rate SARS-CoV-2 and mortality with skin malignancies receiving systemic anti-cancer therapy (SACT) during the Guy’s Cancer Centre. Methods: All SACT Centre between March 1st May 31st 2020 were included. Demographic data: sex, age, socio-economic status (SES),...