Vitoria M Olyntho
- Cell Image Analysis Techniques
- Industrial Vision Systems and Defect Detection
- Scheduling and Optimization Algorithms
- Advanced Biosensing Techniques and Applications
- Lymphoma Diagnosis and Treatment
- Genetics, Bioinformatics, and Biomedical Research
- Acute Lymphoblastic Leukemia research
- Immune Cell Function and Interaction
- CAR-T cell therapy research
- Parasites and Host Interactions
- AI in cancer detection
- Scientific Computing and Data Management
- Biosensors and Analytical Detection
- Single-cell and spatial transcriptomics
- Radiomics and Machine Learning in Medical Imaging
- Child Nutrition and Water Access
McMaster University
2022-2025
Population Health Research Institute
2024
The iterative bleaching extends multiplexity (IBEX) Knowledge-Base is a central portal for researchers adopting IBEX and related 2D 3D immunofluorescence imaging methods. design of the modeled after efforts in open-source software community includes three facets: development platform (GitHub), static website, service data archiving. facilitates practice open science throughout research life cycle by providing validation recommended non-recommended reagents, e.g., primary secondary...
Multiplexed imaging is a powerful approach in spatial biology, although it complex, expensive and labor-intensive. Here, we present the IBEX Knowledge-Base, central resource for reagents, protocols more, to enhance knowledge sharing, optimization innovation of proteomics techniques.
The iterative bleaching extends multiplexity (IBEX) Knowledge-Base is a central portal for researchers adopting IBEX and related 2D 3D immunofluorescence imaging methods. design of the modeled after efforts in open-source software community includes three facets: development platform (GitHub), static website, service data archiving. facilitates practice open science throughout research life cycle by providing validation recommended non-recommended reagents, e.g., primary secondary...
Introduction: Monoclonal antibodies (mAbs) have emerged as a promising immune-oncological approach to target cancer cells. mAbs been seen outperform traditional drug treatments in treating severe cancers despite their low relative cytotoxicity due high selectivity. CD22 is expressed 60-90% of individuals with B-cell Acute Lymphoblastic Leukemia (B-ALL), and rapidly internalized when bound an antibody, making it effective point entry for cytotoxic agents. Epratuzumab anti-CD22 mAb, against...