Vitoria M Olyntho

ORCID: 0000-0003-2634-6838
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About
Contact & Profiles
Research Areas
  • Cell Image Analysis Techniques
  • Industrial Vision Systems and Defect Detection
  • Scheduling and Optimization Algorithms
  • Advanced Biosensing Techniques and Applications
  • Lymphoma Diagnosis and Treatment
  • Genetics, Bioinformatics, and Biomedical Research
  • Acute Lymphoblastic Leukemia research
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Parasites and Host Interactions
  • AI in cancer detection
  • Scientific Computing and Data Management
  • Biosensors and Analytical Detection
  • Single-cell and spatial transcriptomics
  • Radiomics and Machine Learning in Medical Imaging
  • Child Nutrition and Water Access

McMaster University
2022-2025

Population Health Research Institute
2024

The iterative bleaching extends multiplexity (IBEX) Knowledge-Base is a central portal for researchers adopting IBEX and related 2D 3D immunofluorescence imaging methods. design of the modeled after efforts in open-source software community includes three facets: development platform (GitHub), static website, service data archiving. facilitates practice open science throughout research life cycle by providing validation recommended non-recommended reagents, e.g., primary secondary...

10.7554/elife.105737 preprint EN 2025-04-02

Multiplexed imaging is a powerful approach in spatial biology, although it complex, expensive and labor-intensive. Here, we present the IBEX Knowledge-Base, central resource for reagents, protocols more, to enhance knowledge sharing, optimization innovation of proteomics techniques.

10.1371/journal.pbio.3003070 article EN public-domain PLoS Biology 2025-03-19

The iterative bleaching extends multiplexity (IBEX) Knowledge-Base is a central portal for researchers adopting IBEX and related 2D 3D immunofluorescence imaging methods. design of the modeled after efforts in open-source software community includes three facets: development platform (GitHub), static website, service data archiving. facilitates practice open science throughout research life cycle by providing validation recommended non-recommended reagents, e.g., primary secondary...

10.7554/elife.105737.1 preprint EN 2025-04-02

Introduction: Monoclonal antibodies (mAbs) have emerged as a promising immune-oncological approach to target cancer cells. mAbs been seen outperform traditional drug treatments in treating severe cancers despite their low relative cytotoxicity due high selectivity. CD22 is expressed 60-90% of individuals with B-cell Acute Lymphoblastic Leukemia (B-ALL), and rapidly internalized when bound an antibody, making it effective point entry for cytotoxic agents. Epratuzumab anti-CD22 mAb, against...

10.26685/urncst.340 article EN cc-by Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal 2022-04-21
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