A5092519351- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Liver Disease and Transplantation
- Monoclonal and Polyclonal Antibodies Research
- Hepatitis Viruses Studies and Epidemiology
- Cardiac Imaging and Diagnostics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Biosimilars and Bioanalytical Methods
- Oil, Gas, and Environmental Issues
- Pregnancy and Medication Impact
- Immunodeficiency and Autoimmune Disorders
- Solar and Space Plasma Dynamics
- Medical Imaging Techniques and Applications
- Cancer Immunotherapy and Biomarkers
- Neurological Complications and Syndromes
- Innovations in Medical Education
- Organ Transplantation Techniques and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Global Health Workforce Issues
- Adolescent and Pediatric Healthcare
- Primary Care and Health Outcomes
- Gamma-ray bursts and supernovae
Erasmus MC
2023-2025
Erasmus University Rotterdam
2024
<h2>Abstract</h2><h3>Background and Aims</h3> Flares after nucleos(t)ide analogue (NA) cessation are common potentially harmful. Predictors of flares required for risk stratification to guide off-treatment follow-up. <h3>Method</h3> This multicenter cohort study included virally suppressed patients with chronic hepatitis B (CHB) who were e antigen negative at NA cessation. Hepatic defined based on an ALT-levels ≥5-, 10- or 20 x upper limit normal (ULN). Multivariable Cox regression analyses...
Presence of metabolic comorbidities is associated with a higher risk liver-related events in chronic hepatitis B (CHB) patients. However, the association between presence and severity biopsy-proven liver fibrosis yet unknown. Data from CHB patients 2 tertiary clinics 8 clinical trials was analyzed. We studied untreated patients, regression or progression biopsies taken after initiation antiviral therapy (AVT). analyzed 3179 Median age 37 years, 57.6% HBeAg positive, median HBV DNA 7.30...
ABSTRACT Background Severe flares (ALT ≥ 10×ULN) are a well‐recognised adverse outcome after nucleos(t)ide analogue (NA) cessation and may lead to liver failure. Thus, identification of patients at risk for these is major importance. Methods Data were used from two prospective studies on NA conducted in the Netherlands Canada. Patients eligible based EASL criteria. HBcrAg anti‐HBc levels measured end treatment (EOT) week 6 (FUW6). Logistic regression was study association with severe flares....
Background and Aims: Management of Budd-Chiari syndrome (BCS) has improved over the last decades. The main aim was to evaluate contemporary post-liver transplant (post-LT) outcomes in Europe. Approach Results: Data from all patients who underwent transplantation 1976 2020 obtained European Liver Transplant Registry (ELTR). Patients < 16 years, with secondary BCS or HCC were excluded. Patient survival (PS) graft (GS) before after 2000 compared. Multivariate Cox regression analysis...
Samenvatting Het dagelijks werk van een arts bestaat uit patiëntenzorg (eerste vak) en allerlei andere zaken, zoals verandermanagement of beleidsontwikkeling (tweede vak). Op dit moment worden studenten geneeskunde nog onvoldoende op het tweede vak voorbereid. In 2019 zijn wij daarom gestart met nieuw onderwijs binnen de master geneeskunde, waarbij alle vroeg in hun carrière proactief kennismaken vak. Uit huidige evaluatie blijkt dat deelnemers als zeer waardevol ervaren, hoge waarderingen...