A5100731248- DNA and Biological Computing
- Advanced biosensing and bioanalysis techniques
- biodegradable polymer synthesis and properties
- Fungal and yeast genetics research
- Cellular Automata and Applications
- Microtubule and mitosis dynamics
- Advanced Data Storage Technologies
- Polymer crystallization and properties
- Polymer Foaming and Composites
- Chromosomal and Genetic Variations
- Advanced Computational Techniques and Applications
- Polymer Surface Interaction Studies
- Composting and Vermicomposting Techniques
- Cancer-related molecular mechanisms research
- Greenhouse Technology and Climate Control
- Microbial Metabolic Engineering and Bioproduction
- Elevator Systems and Control
- Enzyme Catalysis and Immobilization
- RNA modifications and cancer
- RNA and protein synthesis mechanisms
- Tree Root and Stability Studies
- Remote Sensing and Land Use
- Bioactive natural compounds
- Constructed Wetlands for Wastewater Treatment
- Bacteriophages and microbial interactions
Beijing Technology and Business University
2019-2025
Guiyang Medical University
2023
Southeast University
2023
BGI Group (China)
2017-2023
BGI Research
2022
China National GeneBank
2019-2021
Hong Kong University of Science and Technology
2021
University of Hong Kong
2021
Shenzhen Institutes of Advanced Technology
2020
Wuhan University
2013
INTRODUCTION Although much effort has been devoted to studying yeast in the past few decades, our understanding of this model organism is still limited. Rapidly developing DNA synthesis techniques have made a “build-to-understand” approach feasible reengineer on genome scale. Here, we report completion 770-kilobase synthetic chromosome II (synII). SynII was characterized using extensive Trans-Omics tests. Despite considerable sequence alterations, synII virtually indistinguishable from wild...
Abstract DNA is a promising data storage medium due to its remarkable durability and space-efficient storage. Early bit-to-base transcoding schemes have primarily pursued information density, at the expense of introducing biocompatibility challenges or decoding failure. Here we propose robust algorithm named yin–yang codec, using two rules encode binary bits into one nucleotide, generate sequences that are highly compatible with synthesis sequencing technologies. We encoded representative...
Aneuploidy compromises genomic stability, often leading to embryo inviability, and is frequently associated with tumorigenesis aging. Different aneuploid chromosome stoichiometries lead distinct transcriptomic phenotypic changes, making it helpful study aneuploidy in tightly controlled genetic backgrounds. By deploying the engineered SCRaMbLE (synthetic rearrangement modification by loxP-mediated evolution) system newly synthesized megabase Sc2.0 VII (synVII), we constructed a synthetic...
ABSTRACT Long‐chain branched polypropylene (LCBPP) has become the material of choice for foaming due to its high melt strength and excellent strain hardening properties. In this work, different β‐crystal nucleating agents were melt‐blended with LCBPP. The morphology agents, strength, melting crystallization behavior mixtures characterized using POM, rotational rheometer, XRD, DSC. After selecting agent WBG‐II, high‐temperature self‐assembly was performed. impact mixture containing 5 phr...
Abstract Aneuploidy compromises genomic stability, often leading to embryo inviability, and is frequently associated with tumorigenesis aging. Different aneuploid chromosome stoichiometries lead distinct transcriptomic phenotypic changes, making it helpful study aneuploidy in tightly controlled genetic backgrounds. By deploying the engineered SCRaMbLE system newly synthesized Sc2.0 megabase VII ( synVII ), we constructed a synthetic disomic yeast screened hundreds of SCRaMbLEd derivatives...
Abstract Chamaeleo is currently the only collection library that focuses on adapting multiple well-established coding schemes for DNA storage. It provides a tool researchers to study various and apply them in practice. adheres concept of high aggregation low coupling software design which will enhance performance efficiency. Here, we describe working pipeline Chamaeleo, demonstrate its advantages over implementation existing single schemes. The source code available at...
Background: Colon cancer (CC) is common, and the mortality rate greatly increases as disease progresses to metastatic stage. Early detection of colon (mCC) crucial for reducing rate. Most previous studies have focused on top-ranked differentially expressed transcriptomic biomarkers between mCC primary CC while ignoring non-differentially genes. Results: This study proposed that complicated inter-feature correlations could be quantitatively formulated a complementary view. We used regression...
ABSTRACT It is of great interest and importance to design fabricate the double crystal melting peak (DCMP) structure for expanded polypropylene (EPP) bead foams during sintering. Two kinds methods with different mechanisms were proposed prepare long‐chain‐branched (LCBPP) samples a DCMP structure: One was that prepared by generating crystals perfection degrees other one adding β‐NA produce various forms. In addition, zeolite molecular sieve (ZMS) as synergist introduced into LCBPP/β‐NA...
ABSTRACT DNA is a promising data storage medium due to its remarkable durability and space-efficient storage. Early bit-to-base transcoding schemes have primarily pursued information density, at the expense however of introducing biocompatibility challenges or risk decoding failure. Here, we propose robust algorithm named “Yin-Yang Codec” (YYC), using two rules encode binary bits into one nucleotide, generate sequences highly compatible with synthesis sequencing technologies. We encoded...
Aerobic composting of conventional municipal sludge has always had the problems nitrogen loss and low humification. In this study, biolysed (BS), polyacrylamids-added (PS) Fe (III)/CaO-added (FS) were used for composting, respectively, their effect on physical-chemical parameters, conversion humification during investigated. The results showed that dissolved organic matter (DOM) concentration BS pile (23.1 ± 0.4 g/kg) was 48.4% higher than PS (15.5 FS piles 0.0 in initial stage became lowest...
Video surveillance is an important security technology, which widely use in public areas and police detection utilizing video system a powerful method the investigation that must answer question of five W's on crim. In this paper, HWMSE designed to solve problems case based theories metasynthesis from qualitative quantitative. The proposed constituted four components: Database sub-system information knowledge, man-machine combination toolsets analysis, deduction simulation crime behavior...
Trees' computer modeling has been widely used in the construction of a virtual natural scene. Poplar, as common tree species mid-latitude region, is very essential real landscape. Up to now, models libraries many commonly applications on growth simulation, it hard find poplar models. In this paper, result analysis and statistics measured shape parameters data trends some 3-year Populur × euramericana cv. "74/76" (Poplar 107) trees was shown at first. And then Poplar 107 were established...
Abstract DNA is a promising data storage medium due to its remarkable durability and space-efficient storage. Early bit-to-base transcoding schemes have primarily pursued information density, at the expense however of introducing biocompatibility challenges or risk decoding failure. Here, we propose robust algorithm named “Yin-Yang Codec” (YYC), using two rules encode binary bits into one nucleotide, generate sequences highly compatible with synthesis sequencing technologies. We encoded...
Escalator as special equipment is one of vertical transportation tools. In order to strengthen energy performance supervision, national standard commitment issued relative efficiency test and classification for escalator. This paper introduces method The main procedure evaluation criterion escalator are also clarified. Field carried out results given discussed promote the application this method.
Throughout the coronavirus disease 2019 (COVID-19) pandemic, continuous genomic evolution of its etiological agent, severe acute respiratory syndrome 2 (SARS-CoV-2), has generated many new variants with enhanced transmissibility and immune escape capabilities. Being an essential mediator infections a key target antibodies, mutations spike glycoprotein play vital role in modulating evolutionary trajectory. Here, we present time-resolved statistical method, Dynamic Expedition Leading Mutations...