A5101922515- Shoulder Injury and Treatment
- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Orthopedic Surgery and Rehabilitation
- Bone and Joint Diseases
- Hip disorders and treatments
- Musculoskeletal synovial abnormalities and treatments
- Elbow and Forearm Trauma Treatment
- Cytokine Signaling Pathways and Interactions
- Shoulder and Clavicle Injuries
- Silk-based biomaterials and applications
- RNA Interference and Gene Delivery
- Bone Tissue Engineering Materials
- Osteoarthritis Treatment and Mechanisms
- Autoimmune and Inflammatory Disorders Research
- Cancer-related molecular mechanisms research
- Mesenchymal stem cell research
- Kidney Stones and Urolithiasis Treatments
- Tissue Engineering and Regenerative Medicine
- COVID-19 diagnosis using AI
- Dermatological and COVID-19 studies
- 3D Printing in Biomedical Research
- Autophagy in Disease and Therapy
- Multiple and Secondary Primary Cancers
- Diabetic Foot Ulcer Assessment and Management
Union Hospital
2011-2025
Huazhong University of Science and Technology
2013-2025
China Medical University
2025
Fourth Affiliated Hospital of China Medical University
2025
Union Hospital
2017-2020
Wuhan Union Hospital
2014-2017
In situ tissue engineering is a powerful strategy for the treatment of bone defects. It could overcome limitations traditional engineering, which typically involves extensive cell expansion steps, low survival rates upon transplantation, and risk immuno-rejection. Here, porous scaffold polycaprolactone (PCL)/decellularized small intestine submucosa (SIS) was fabricated via cryogenic free-form extrusion, followed by surface modification with aptamer PlGF-2123-144*-fused BMP2 (pBMP2). The two...
Inflammation is a contributing factor in osteocyte apoptosis, which strongly associated with the development of glucocorticoid-associated osteonecrosis femoral head (GA-ONFH). Curcumin naturally derived drug that regulates immunity and inhibits inflammation. This study aimed to examine capacity curcumin prevent apoptosis GA-ONFH, while elucidating possible mechanisms action. C57/BL6 female mice were divided into control, curcumin-treated GA-ONFH groups. We determined effect on polarization...
Gluteal muscle contracture (GMC), a debilitating disease, exists all over the globe but it is much more prevalent in China. Patients typically present with abduction and external rotation of hip are unable to bring both knees together while squatting. Multiple etiologies have been postulated, commonest being repeated intramuscular injection into buttocks. The disease diagnosed primarily by clinical features radiological necessary for exclusion other pathological conditions. Non-operative...
Primary purpose of this study is to compare the clinical outcomes patients undergoing arthroscopic arthrolysis in posttraumatic and non-traumatic elbow stiffness. Secondary aims are level satisfaction complications.We retrospectively evaluated between January 2008 September 2015 have completed a minimum 2-year follow-up. Total 141 (male = 90; female 51) with 143 elbows (posttraumatic, n 75; non-traumatic, 68) an average age 33 years were available for final evaluation. The follow-up period...
Purpose To compare the clinical effects of endoscopic surgeries with traditional open in treatment gluteal muscle contracture and discuss their indications value. Methods In this retrospective study, 50 patients received 52 surgeries. The 2 groups were compared terms surgery duration, incision lengths, postsurgical pain, complications, off-bed activity times, hospitalization outcome, 1-year recurrence rates. Result group was significantly superior to regard length, time, patient cosmetic...
Ideal bone tissue engineering scaffolds composed of extracellular matrix (ECM) require excellent osteoconductive ability to imitate the environment. We developed a mineralised tissue-derived ECM-modified true ceramic (TBC) scaffold for delivery aspartic acid-modified morphogenic protein-2 (BMP-2) peptide (P28) and assessed its osteogenic capacity. Decellularized ECM from porcine small intestinal submucosa (SIS) was coated onto surface TBC, followed by mineralisation modification (mSIS/TBC)....
<h2>Abstract</h2> The main method for arthroscopic repair of the subscapularis is with suture anchors. surgeon generally establishes anterior and anterolateral operation portals to complete anchor implantation passing, respectively. single–operation portal technique has been developed recently. However, in traditional technique, device grasper are difficult operate simultaneously. In addition, rotator cuff device, it easy cause further iatrogenic injury because its larger diameter....
Abstract A water‐soluble polysaccharide (APP‐AW) was isolated from Agrimonia pilosa and prepared to three sulphated derivatives (S1, S2 S3). The results showed that pre‐treatment with APP‐AW, S1, S3 each at the concentration of 50 μg/mL for 48 hours able prevent cytotoxicity induced by 1 μmol/L dexamethasone (Dex) in MC3T3‐E1 cells via inhibition apoptosis, which is line findings flow cytometry analysis. Meanwhile, decreased ALP activity, collagen content, mineralization, BMP2, Runx2, OSX...
Tears in the lateral meniscus, especially body and posterior horn, are a common sports medicine injury, severe cases require arthroscopic treatment. However, narrow space posterolateral compartment of knee joint makes surgeon's operation inconvenient. Here we have proposed suture technique suitable for meniscus horn/body injuries known as Chinese Union Suture Procedure. The introduction posteromedial-transseptal portal allows angle hooks case to horn or popliteal hiatus area meniscus. use...
Abstract: Coronavirus disease 2019 (COVID-19) is spreading worldwide, with its outlook not looking optimistic. Simultaneously, the epidemic currently under control in many areas. The resumption of work and production areas that have achieved outbreaks a problem. Considering extremely transmissible nature COVID-19, presence asymptomatic infected people, avoiding nosocomial infection protecting medical staff patients during post-epidemic period remain difficult problems need to be solved. At...