- Developmental Biology and Gene Regulation
- Genomics and Chromatin Dynamics
- Genomics and Phylogenetic Studies
- Epigenetics and DNA Methylation
- Genomic variations and chromosomal abnormalities
- Photosynthetic Processes and Mechanisms
- Arsenic contamination and mitigation
- Genetics and Neurodevelopmental Disorders
- CRISPR and Genetic Engineering
- Enzyme-mediated dye degradation
- Bacteriophages and microbial interactions
- Insect Resistance and Genetics
- Hippo pathway signaling and YAP/TAZ
- Polysaccharides and Plant Cell Walls
- Polyamine Metabolism and Applications
- Genomics and Rare Diseases
- Viral Infectious Diseases and Gene Expression in Insects
- Kruppel-like factors research
- Antimicrobial Peptides and Activities
- Fungal Biology and Applications
- Cancer-related gene regulation
- Invertebrate Immune Response Mechanisms
- Autism Spectrum Disorder Research
- Polysaccharides Composition and Applications
- Wnt/β-catenin signaling in development and cancer
Center for Excellence in Brain Science and Intelligence Technology
2025
Chinese Academy of Sciences
2025
Yangzhou University
2022-2024
Kunming University of Science and Technology
2024
Sun Yat-sen University
2024
Southeast University
2021-2022
Nanjing Medical University
2022
Hospital for Sick Children
2006
SickKids Foundation
2006
University of Toronto
2006
The flowering of Amorphophallus bulbifer plays an important role in its reproduction. flowers and leaves A. cannot grow at the same time. However, physiological molecular mechanisms involved flower bud leaf formation are still unclear. In this study, buds early stage growth were used as research materials, transcriptome metabolome analyses carried out, soluble sugar starch contents corms determined. Transcriptome analysis revealed 5 542 differentially expressed genes (DEG) between buds, 3...
ABSTRACT The evolutionarily conserved C-terminal binding protein (CtBP) has been well characterized as a transcriptional co-repressor. Herein, we report previously unreported function for CtBP, showing that lowering CtBP dosage genetically suppresses Polycomb group (PcG) loss-of-function phenotypes while enhancing of trithorax (trxG) in Drosophila, suggesting the role gene activation is more pronounced fly development than thought. In cells, show required derepression most direct PcG target...
During Drosophila development, Polycomb-group and Trithorax group proteins function to ensure correct maintenance of transcription patterns by epigenetically repressing or activating target gene expression. To get a deep insight into the PcG trxG pathways, we investigated BRCT domain-containing protein called PTIP, which was generally identified as transcriptional coactivator belongs TRR complex. At genome scale, sorted given PTIP-binding peaks two groups: PTIP/TRR-cobound PTIP/PC-cobound...
Tree peony (Paeonia ostii) is an important ornamental plant with high oil and medical values widely distributed in China. In order to explore the effects of sucrose treatment on growth P. ostii seeds identify key genes involved metabolism transport during early development seeds, comparative transcriptome sequencing seed coats endosperms at 50 days after flowering (DAF) without supply were conducted using Illumina HiSeq platform. A total 97,976 unigenes obtained annotated seven public...
Summary In eukaryotes, histone modifications are key epigenetic regulators that associated with distinct chromatin features. Bivalent describe a situation where subset of promoters have both activating (H3K4me3) and repressive (H3K27me3) markers in pluripotent cells (e.g., ESCs). However, it remains to be understood whether bivalent stable throughout developmental stages. Here, by systematically analyzing ChIP‐seq data H3K4me3 H3K27me3, we provided the first panoramic view Drosophila from...
<title>Abstract</title> Trehalose-6-phosphate synthase (TPS) as a key enzyme in trehalose metabolism plays important roles metabolic regulation and abiotic stress tolerance many species. In our previous study, 10 <italic>TPS</italic> family members <italic>Paeonia ostii</italic> have been identified, among them <italic>PoTPS1</italic> <italic>PoTPS5</italic> were regarded critical genes regulating growth development of <italic>P. ostii</italic>. this the full-length cDNAs with 1698...