Chad R. Ishmael

ORCID: 0000-0003-3204-9354
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About
Contact & Profiles
Research Areas
  • Orthopedic Infections and Treatments
  • Orthopaedic implants and arthroplasty
  • Shoulder Injury and Treatment
  • Total Knee Arthroplasty Outcomes
  • Shoulder and Clavicle Injuries
  • Innovations in Medical Education
  • Diversity and Career in Medicine
  • Spine and Intervertebral Disc Pathology
  • Medical Education and Admissions
  • Infectious Diseases and Tuberculosis
  • Spinal Fractures and Fixation Techniques
  • Antimicrobial Resistance in Staphylococcus
  • Sarcoma Diagnosis and Treatment
  • Surgical site infection prevention
  • Global Health and Surgery
  • Musculoskeletal Disorders and Rehabilitation
  • Bacterial biofilms and quorum sensing
  • Bone Metabolism and Diseases
  • Cardiac Arrhythmias and Treatments
  • Injury Epidemiology and Prevention
  • Blood transfusion and management
  • Automotive and Human Injury Biomechanics
  • Bone health and treatments
  • Nerve Injury and Rehabilitation
  • Musculoskeletal synovial abnormalities and treatments

University of California, Los Angeles
2016-2024

Johns Hopkins University
2023

Orthopaedic Hospital
2021

Musculoskeletal Transplant Foundation
2018

Hospital for Special Surgery
2015

Cornell University
2013-2015

Background: There is a new method of transportation that started in our community late 2017— rideshare electric scooters (e-scooters). These have proven immensely popular and can now be found many cities around the world. Despite pervasiveness e-scooters, their associated injury patterns are poorly understood. The purpose this study was to describe department’s experience at epicenter e-scooter phenomenon sweeping globe characterize operative orthopaedic injuries related accidents. Methods:...

10.2106/jbjs.19.00390 article EN Journal of Bone and Joint Surgery 2019-12-30

Background: The current U.S. orthopaedic residency application process is becoming increasingly impersonal in the wake of an increasing number applications. Through analysis surgery statistics, we have highlighted effect that applications has on match rate, and suggested methods for a more personalized process. Methods: Data from Association American Medical Colleges (AAMC) National Resident Matching Program (NRMP) United States applicants 2008 to 2018 were collected. These data included...

10.2106/jbjs.19.00930 article EN Journal of Bone and Joint Surgery 2020-01-05

Abstract Implant related infections are the most common cause of joint arthroplasty failure, requiring revision surgeries and a new implant, resulting in cost $8.6 billion annually. To address this problem, we created class coating technology that is applied operating room, procedure takes less than 10 min, can incorporate any desired antibiotic. Our uses an situ coupling reaction branched poly(ethylene glycol) poly(allyl mercaptan) (PEG-PAM) polymers to generate amphiphilic polymeric...

10.1038/s41467-021-25383-z article EN cc-by Nature Communications 2021-09-16

Platelet-rich plasma (PRP) has emerged as a popular biologic treatment for musculoskeletal injuries and conditions. Despite numerous investigations on the efficacy of PRP therapy, current utilization this within United States is not widely known.To investigate national PRP, including incidence conditions which it used in clinical setting, to determine charges associated with treatment.Descriptive epidemiology study.Using database (PearlDiver) private insurance billing records, we conducted...

10.1177/2325967116676241 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2016-12-01

Medicare insures the largest population of patients at risk for rotator cuff tears in United States.To evaluate trends incidence, concomitant procedures, and complications with open arthroscopic repairs patients.Cohort study; Level evidence, 3.All who had undergone or repair from 2005 through 2011 were identified a claims database. Annual postoperative compared between these 2 groups.In total, 372,109 analyzed. The incidence decreased (from 6.0 to 4.3 per 10,000 patients, P < .001) while...

10.1177/2325967117731310 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2017-10-01

Abstract Extremity reconstruction surgery is increasingly performed rather than amputation for patients with large-segment pathologic bone loss. Debate persists as to the optimal void filler this “limb salvage” surgery, whether metal or allograft bone. Clinicians focus on optimizing important functional gains patients, and risk of devastating implant infection has been thought be similar regardless material. Recent insights into pathophysiology are challenging equipoise, however, both basic...

10.1038/s41413-020-00118-w article EN cc-by Bone Research 2020-12-10

Aims Aseptic loosening is a major cause of failure in cemented endoprosthetic reconstructions. This paper presents the long-term outcomes custom-designed cross-pin fixation construct designed to minimize rotational stress and subsequent aseptic selected patients. The will also examine survivorship modes when using this technique. Patients Methods A review 658 consecutive, prospectively collected reconstructions for oncological diagnoses at single centre between 1980 2017 was performed. total...

10.1302/0301-620x.101b6.bjj-2018-0993.r1 article EN The Bone & Joint Journal 2019-06-01

Drug-resistant Gram-positive bacterial infections are still a substantial burden on the public health system, with two bacteria ( Staphylococcus aureus and Streptococcus pneumoniae ) accounting for over 1.5 million drug-resistant in United States alone 2017. In 2019, 250,000 deaths were attributed to these pathogens globally. We have developed preclinical glycopeptide antibiotic, MCC5145, that has excellent potency (MIC 90 ≤ 0.06 μg/ml) against hundreds of isolates methicillin-resistant S....

10.1126/scitranslmed.abj2381 article EN Science Translational Medicine 2022-09-14

Globally, the burden of musculoskeletal conditions continues to rise, disproportionately affecting low and middle-income countries (LMICs). The ability meet these orthopaedic surgical care demands remains a challenge. To help address issues, many surgeons seek opportunities provide humanitarian assistance populations in need. While global initiatives are well-intentioned can offer short-term benefits local communities, it is essential emphasize training integration surgeon-leaders....

10.2106/jbjs.21.00948 article EN cc-by-nc-nd Journal of Bone and Joint Surgery 2021-12-21

Introduction: Finding a first job after fellowship can be stressful due to the uncertainty about which resources utilize, including program directors (PDs), residency faculty and other sources. There are over 90 orthopaedic trauma fellows seeking jobs annually. We surveyed determine search process. Methods: An anonymous 37 question survey was created online sent from five fellowship-cycle years of 2016 – 2021. The primary questions were related process, current job, work details. secondary...

10.1097/bot.0000000000002744 article EN Journal of Orthopaedic Trauma 2023-12-20

BackgroundShoulder instability is commonly treated by arthroscopic stabilization. However, open stabilization procedures remain important in management of complex instability. Despite continued use these procedures, the relative frequency related complications remains poorly described. This study investigates current trends shoulder and characterizes major postoperative complications.MethodsPearlDiver, a national insurance database orthopedic patients, was used to identify from 2007 2010....

10.1016/j.jses.2017.07.001 article EN cc-by-nc-nd JSES Open Access 2017-06-01

<h3>ABSTRACT</h3> <h3>Background:</h3> Cervical laminoplasty and laminectomy fusion (LF) are posterior-based surgical techniques for the treatment of cervical spondylotic myelopathy (CSM). Interestingly, comparative amount spinal cord drift obtained from these procedures has not been extensively described. The purpose this study is to compare between LF in patients with CSM. <h3>Methods:</h3> group consisted 22 patients, 44 patients. Preoperative postoperative alignment was measured using...

10.14444/8028 article EN The International Journal of Spine Surgery 2021-04-01

Introduction: Periprosthetic joint infection (PJI) remains a challenging complication of replacement surgery. With the more frequent use immune modifying drugs and dietary changes in human populations, resultant blunting defenses allows for infections with less common organisms. Case Report: Lactococcus garvieae is an anaerobic, gram-positive coccus reservoirs fish domesticated farm animals. Only two prior cases PJI due to L. have been reported, both reported marine transmission. We report...

10.13107/jocr.2022.v12.i11.3422 article EN cc-by-nc Journal of Orthopaedic Case Reports 2022-01-01

Spine implant infections portend poor outcomes as diagnosis is challenging and surgical eradication at odds with mechanical spinal stability. The purpose of this method to describe a novel mouse model infection (SII) that was created provide an inexpensive, rapid, accurate in vivo tool test potential therapeutics treatment strategies for infections. In method, we present posterior-approach surgery which stainless-steel k-wire transfixed into the L4 spinous process 12-week old C57BL/6J...

10.3791/60560 article EN Journal of Visualized Experiments 2020-06-23

A prospective study of a new technique.The aims this were to report manual technique for measuring vertebral curves on digital spine radiographs, and assess the agreement with that software curves.Modern picture archiving communication systems (PACS) typically include evaluating radiographic measurements. However, in outpatient setting, patients may present radiographs stored physical disc, which not curves. Certain smartphone applications be used determine curve magnitude; however, need...

10.1097/bsd.0000000000000070 article EN Clinical Spine Surgery A Spine Publication 2013-12-11

Assessing academic productivity allows departments to identify the strengths of their scholarly contribution and provides an opportunity evaluate areas for improvement.To provide objective benchmarks seeking enhance those with significant improvement in recent past.Our study retrospectively analyzed a cohort orthopaedic faculty at United States-based programs. 5502 full-time representing 178 programs were included analysis. Variables analysis National Institutes Health funding (2014-2018),...

10.5312/wjo.v13.i2.201 article EN World Journal of Orthopedics 2022-02-18

In this report, we present the case of an 80-year-old female with pain located over tip her cemented tibial stem in a revision hinge total knee arthroplasty localized osteolysis that looked suspicious for infection. A thorough workup was negative We postulate at end initiated by modulus elasticity mismatch tip, which generated focal area increased sagittal bone bending and microparticle generation. She treated lesional exploration, debridement, synthetic grafting, plating to distribute...

10.1016/j.artd.2022.01.030 article EN cc-by-nc-nd Arthroplasty Today 2022-03-09

With the aging population, demand for total hip arthroplasty is rising. Improvements in techniques and design allow to be increasingly performed older patients those with multiple comorbidities. Complications are rare young healthy patients; however, there greater risk medical comorbidities who have had prior revision procedures. Large-vessel thrombosis an especially rare, but potentially devastating, complication, particularly existing major-vessel bypass grafts. Only 3 case reports of...

10.1016/j.artd.2021.01.002 article EN cc-by-nc-nd Arthroplasty Today 2021-02-27
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