A5103028188- Bone health and osteoporosis research
- Animal Genetics and Reproduction
- Genetic Associations and Epidemiology
- Sexual function and dysfunction studies
- Vitamin C and Antioxidants Research
- Burn Injury Management and Outcomes
- Dietary Effects on Health
- Amyotrophic Lateral Sclerosis Research
- Body Composition Measurement Techniques
- Salivary Gland Disorders and Functions
- Oral microbiology and periodontitis research
- Blood groups and transfusion
- Pancreatic and Hepatic Oncology Research
- Reproductive Biology and Fertility
- Cardiac Valve Diseases and Treatments
- Gastrointestinal Tumor Research and Treatment
- LGBTQ Health, Identity, and Policy
- Microgrid Control and Optimization
- Thermal Regulation in Medicine
- Attention Deficit Hyperactivity Disorder
- RNA Interference and Gene Delivery
- Biomarkers in Disease Mechanisms
- Connective Tissue Growth Factor Research
- Autophagy in Disease and Therapy
- Genomics, phytochemicals, and oxidative stress
Southern Medical University
2021-2024
Guangdong Academy of Medical Sciences
2021-2024
Soochow University
2020-2021
People's Hospital of Xinjiang Uygur Autonomous Region
2021
Guangdong Provincial People's Hospital
2021
Second Hospital of Shandong University
2021
First Affiliated Hospital of Soochow University
2020
MRC Centre for Regenerative Medicine
2018
University of Edinburgh
2018
Hangzhou Medical College
2018
Mutations in C9ORF72 are the most common cause of familial amyotrophic lateral sclerosis (ALS). Here, through a combination RNA-Seq and electrophysiological studies on induced pluripotent stem cell (iPSC)-derived motor neurons (MNs), we show that increased expression GluA1 AMPA receptor (AMPAR) subunit occurs MNs with mutations leads to Ca2+-permeable AMPAR results enhanced selective MN vulnerability excitotoxicity. These deficits not found iPSC-derived cortical abolished by...
Abstract Childhood obesity is an established risk factor for metabolic disease. The influence of on bone development, however, remains controversial and may depend the pattern regional fat deposition. Therefore, we examined associations compartments calf thigh with weight-bearing parameters in girls. Data from 444 girls aged 9 to 12 years Jump-In: Building Better Bones study were analyzed. Peripheral quantitative computed tomography (pQCT) was used assess at metaphyseal diaphyseal sites...
Disturbances in mineral metabolism are associated with lower bone density and fracture; however, previous human studies have assessed individual markers isolation. We serum concentrations of 25-hydroxyvitamin D (25-OHD), PTH, bone-specific alkaline phosphatase (BAP) individually, combination, association the long-term risk hip fracture among a general population older adults. studied 2294 participants from Cardiovascular Health Study (mean age 74 yr) who were ambulatory free known...
Background To discover how NLRP 3 and TNFRSF 1A polymorphisms affect the efficacy of traditional medicine etanercept for ankylosing spondylitis ( AS ) patients. Methods Single nucleotide polymorphism SNP haplotype analyses were conducted based on determined among We subsequently analyzed relationship between relevant clinical indexes . Results The 4 loci showed significant linkage disequilibrium, respectively. T allele rs4612666 TFRSF rs4149570 are both associated with P <.05). T‐A‐C‐T as...
// Zhao Chen 1,* , Yiran Zhang Liang Ma 1 Yiming Ni and Haige Department of Cardiothoracic Surgery, The First Affiliated Hospital, School Medicine, Zhejiang University, Hangzhou, Zhejiang, China * These authors have contributed equally to this study Correspondence to: Zhao, email: Keywords : Nrf2, burn trauma, intestinal injury, systemic inflammation, Immunology Microbiology Section, Immune response, Immunity Received January 09, 2016 Accepted March 05, Published 18, Abstract Nuclear factor...
Beego is a traditional Chinese complete water-only fasting practice initially developed for spiritual purposes, later extending to physical fitness purposes. notably includes psychological induction component that meditation and abdominal breathing, light body exercise ends with specific gradual refeeding program before returning normal diet. has regained its popularity in recent decades China as strategy helping people subhealthy conditions or metabolic syndrome, but we are unaware of any...
Both genes and environment have been implicated in determining the complex body composition phenotypes individuals of European ancestry; however, few studies conducted other race/ethnic groups. We a genome-wide admixture mapping study an attempt to localize novel genomic regions associated with genetic ancestry. selected sample 842 African-American women from Women's Health Initiative single nucleotide polymorphism (SNP) Association Resource for whom several dual-energy X-ray absorptiometry...
This study was performed to examine the implications of microgravity on circulating primordial germ cells (PGCs) offspring silky chickens at stages 13 17. China's ShenZhou-3 unmanned spaceship launched March 25, 2002, 22: 00 Beijing time (14: 00GMT). The carried nine fertilized chicken eggs (F0) test reliability life-support system in space environment. One female and two male were born from these eggs. three mated naturally F1 collected. Blood collected dorsal aorta or marginal vein embryos...
The aims of the present study was to compare midterm results quadrangular leaflet resection versus chordal replacement for repair degenerative posterior mitral (PML) prolapse, and explore risk factors recurrent severe regurgitation (MR).From January 2012 December 2018, 1,423 consecutive patients underwent valve (MV) repair. A total 317 had PML prolapse constituted population. Of these, 74 (23.3%) resection, 243 (76.7%) replacement. Outcomes were compared by using unadjusted data propensity...
An enzymatic method of isolating primary follicles in the turkey has been described previously, but no similar work done hen. In this study, from domestic hens (Gallus domesticus) were isolated using an method, and follicular quantity, quality, development vitro assessed. About 400 ranging 60 to 1125 μm diameter recovered with trypsin collagenase hen ovaries (per ovary). Of these, 76.5% intact a complete single layer granulose cells surrounded by basement membrane, their ultrastructures...
Abstract The aim of the present study was to investigate associations between single nucleotide polymorphisms (SNPs) in PDZ and LIM domain protein 4 (PDLIM4) gene susceptibility osteoporotic fracture an elderly Han Chinese population. Seven SNPs PDLIM4, including rs77584624, rs78418541, rs270611, rs3900945, rs77486529, rs71583465, rs366512, were examined 540 patients with fractures (case group) healthy subjects (control using Sanger sequencing. A-allele carriers rs270611 PDLIM4 had a...
Objectives Intussusception is one of the most common abdominal emergencies in early children. recurs 8–20% children after successful nonoperative reduction. The aim this study was to explore ultrasound findings predict risk recurrence pediatric intussusception air enema Methods A total 336 were followed up for 1 year received They divided into recurrent group and non‐recurrent group. differences clinical characteristics, ultrasonic features, laboratory tests analyzed by univariate analyses...
Objective: To explore a simple, rapid and efficient method for the diagnosis of oral candidiasis in clinical practice. Methods: Totally 124 consecutive patients with suspected were enrolled from Department Oral Medicine, Peking University School Hospital Stomatology, Beijing, China. Exfoliated cells mucosa saliva or concentrated rinse) obtained all participants tested by three smear methods(10% KOH smear, gram-stained Congo red stained smear). The diagnostic efficacy(sensitivity,...
You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Basic Research1 Apr 2011749 NEUROPHYSIOLOGY OF THREE PHASES CORPORAL RELAXATION ELICITED BY ELECTRICAL FIELD STIMULATION ON RABBIT CORPUS CAVERNOSUM SMOOTH MUSCLE Chen Zhao, Jai Seong Cha, and Jong Kwan Park ZhaoChen Zhao Jeonju, Korea, Republic , ChaJai Cha ParkJong View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.1774AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints...
A defective penile prosthesis is disconcerting for the surgeon performingan implantation in a patient with erectile dysfunction.We became aware of Titan justafter insertion left cylinder, which had an abnormal rotation(180 degrees) due to rotated tubing, occurred atthe manufacturing plant. We successfully performed implantationby cutting and re-connecting tubing between cylinderand pump spare connector. When encountersa rotation cylinderdue operative field, disconnectionand re-connection...
To investigate whether the genetically modified somatic cells can survive and express foreign gene for a long time after being transplanted into avian embryo, chicken embryonic fibroblasts (CEFs) as cell vehicle delivering protein were transfected with green fluorescent (GFP) gene, introduced early embryos via blood vessel microinjection at 65-70h of incubation 38.5°C. The manipulated eggs continued to incubate same condition. chimerisms CEFs preliminarily observed under fluorescence...
Objective To study the relationship between jejunal-ileum lesions and terminal ileum of patients with isolated small intestinal Crohn disease, to compare clinical endoscopic features having normal those abnormal in disease. Methods The data diagnosed as disease successively receiving colonoscopy bowel capsule endoscopy Nanfang Hospital Southern Medical University from January 2008 October 2015 were retrospectively analyzed. The divided into group according result colonoscopy. two...
Summary Beego is a traditional Chinese complete water-only fasting practice initially developed for spiritual purposes, later extending to physical fitness purposes. notably includes psychological induction component that meditation and abdominal breathing, light body exercise, ends with specific gradual refeeding program before returning normal diet. has regained its popularity in recent decades China as strategy helping people subhealthy conditions or metabolic syndrome, but we are unaware...