A5088582999- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiovascular and Diving-Related Complications
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Trauma and Emergency Care Studies
- Coronary Interventions and Diagnostics
- Trauma Management and Diagnosis
- Aortic Disease and Treatment Approaches
- Cardiac Arrhythmias and Treatments
- Venous Thromboembolism Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Cerebral Venous Sinus Thrombosis
- Pulmonary Hypertension Research and Treatments
- Retinal and Optic Conditions
- Infective Endocarditis Diagnosis and Management
- Antimicrobial Resistance in Staphylococcus
- Biomarkers in Disease Mechanisms
- Cardiac Fibrosis and Remodeling
- S100 Proteins and Annexins
- Atrial Fibrillation Management and Outcomes
Ljubljana University Medical Centre
2009-2025
University of Ljubljana
2023-2025
University Medical Center
2024
High-risk acute pulmonary embolism (PE) is a life-threatening condition necessitating hemodynamic stabilization and rapid restoration of perfusion. In this context, evidence regarding the benefit advanced circulatory support recanalization strategies still limited. observational study, we assessed data 1060 patients treated for high-risk PE with 991 being included in target trial emulation to investigate all-cause in-hospital mortality estimates different treatment strategies. The four...
The use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) for temporary mechanical circulatory support in various clinical scenarios has been increasing consistently, despite the lack sufficient evidence regarding its benefit and safety from adequately powered randomized controlled trials. Although ARREST trial (Advanced Reperfusion Strategies Patients with Out-of-Hospital Cardiac Arrest Refractory Ventricular Fibrillation) a secondary analysis PRAGUE OHCA (Prague Arrest)...
Extracorporeal life support (ECLS) has been increasingly used in the treatment of severe infarct-related cardiogenic shock last decade. The randomised ECLS-SHOCK trial demonstrated no benefit early routine use on 30-day all-cause death. We herein present mid-term results. At 1-year follow-up, there were significant differences or cardiovascular mortality, neurologic outcome, recurrent myocardial infarction, repeat revascularisation and rehospitalisations for heart failure between ECLS usual...
We investigated echocardiographic and hemodynamic effects of intraaortic balloon pump (IABP) in 26 patients with cardiogenic shock on veno-arterial membrane oxygenation (VA ECMO). Our study demonstrated an 8.1% increase left ventricular velocity time integral (p = 0.023) without reduction diameters 4.7% decrease right end diastolic base diameter 0.05) when using IABP 1:1 mode compared to no augmentation. This was associated a 3.2% heart rate < 0.001) 3.0% mixed venous oxygen saturation...
Abstract Aims We analysed consecutive patients with acute myocardial infarction complicated by cardiogenic shock (CS) who were enrolled into the CULPRIT-SHOCK randomized controlled trial (RCT) and those exclusion criteria included accompanying registry. Methods results In total, 1075 infarct-related CS screened for in 83 specialized centres Europe; 369 of them had RCT Patients followed over 1 year. The mean age was 68 years 260 (25%) women. 13.5%, 30.9%, 55.6% one-vessel, two-vessel,...
Abstract Objectives To compare transesophageal echocardiography (TOE) findings after patent foramen ovale (PFO) closure by BioSTAR (NMT Medical Inc, Boston, MA) and Amplatzer PFO occluders (Abbott Vascular, Plymouth, MN). Background with a biodegradable device represents an attractive alternative to permanent devices. Long‐term effectiveness morphology biodegradation remain unknown. Methods Between February 2008 June 2014, 49 patients received 48 occluder. TOE was performed closure, at 6...
Because re-establishment of spontaneous circulation (ROSC) in patients with cardiac arrest is frequently not achieved by conventional cardiopulmonary resuscitation (C-CPR), selected may undergo extracorporeal membrane oxygenation (E-CPR). We compared angiographic features and percutaneous coronary intervention (PCI) between undergoing E-CPR those ROSC after C-CPR.Forty-nine consecutive immediate angiography admitted August 2013 2022 were matched to 49 C-CPR. Multivessel disease (69.4% vs....
Cardiovascular and inflammatory biomarkers in therapeutic hypothermia have been studied cardiac arrest, but data on patients with ST-segment elevation myocardial infarction (STEMI) treated are currently unavailable. A multiplex proximity extension assay allowed us to measure 157 cardiovascular disease (CVD) disease-related from the international, multicenter, randomized trial; CHILL-myocardial (MI) explore associations of biomarkers. Blood samples were obtained 119 STEMI, as adjunctive...
Background: COVID-19 infection has been associated with paradoxical thromboembolism through a patent foramen ovale (PFO) and ischaemic stroke. Such events have not reported after vaccination. The aim of the present study was to investigate PFO-associated stroke during mass vaccination in Slovenia. Methods: This prospective study, conducted between 26 December 2020 31 March 2022, enrolled consecutive patients (≥18 years) referred for percutaneous closure single interventional facility...
This study aimed to investigate the risk and mechanisms of air entry into extracorporeal membrane oxygenation (ECMO) circuit through central venous catheter (CVC) in a veno-venous configuration. The primary goal was assess impact different volumes on ECMO performance at varying pump speeds.
<title>Abstract</title> Air embolism can complicate extracorporeal membrane oxygenation (ECMO), as the negative pressure in venous system unintentionally draw air. This air disrupt pump function or enter patient through oxygenator, resulting systemic embolism. To examine this risk, a circuit model was created to study entry central catheter (CVC) and its impact on ECMO performance at varying speeds veno-venous configuration. The research revealed that unprotected lumen of CVC is potential...
Background: Infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI) is a rare complication with high morbidity and mortality. Methods: Of 630 consecutive patients undergoing TAVI, 6 (0.95%) presented IE. Results: Four were men, mean age was 81.3 ± 2.2 years all the symptomatic. Left ventricular ejection fraction (LVEF) 56.8 5.3%. The procedure successful in one moderate regurgitation. Two required definitive pacemaker lead had to be reimplanted 24 hours later 1...
Introduction: Because reestablishment of spontaneous circulation (ROSC) is frequently not achieved by conventional cardiopulmonary resuscitation (C-CPR), selected patients undergo with extracorporeal membrane oxygenation (E-CPR). If coronary cause suspected, angiography (CAG) and percutaneous intervention (PCI) are performed. Hypothesis: Coronary anatomy in E-CPR more complex. Despite decreased retrograde aortic blood flow, PCI feasible successful. Methods: Forty-three consecutive undergoing...