Yi Lu

ORCID: 0000-0003-3469-2327
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About
Contact & Profiles
Research Areas
  • Probability and Risk Models
  • Insurance, Mortality, Demography, Risk Management
  • Statistical Distribution Estimation and Applications
  • Financial Risk and Volatility Modeling
  • Tropical and Extratropical Cyclones Research
  • Image Retrieval and Classification Techniques
  • Handwritten Text Recognition Techniques
  • Medical Image Segmentation Techniques
  • Image and Object Detection Techniques
  • Flood Risk Assessment and Management
  • Genetic and Kidney Cyst Diseases
  • Renal and related cancers
  • Stochastic processes and financial applications
  • Advanced Image and Video Retrieval Techniques
  • Neural Networks and Applications
  • Epigenetics and DNA Methylation
  • Vehicle License Plate Recognition
  • Insurance and Financial Risk Management
  • Advanced Vision and Imaging
  • Infrared Target Detection Methodologies
  • Fault Detection and Control Systems
  • Advanced Neural Network Applications
  • bioluminescence and chemiluminescence research
  • Hydrology and Drought Analysis
  • Genetics, Aging, and Longevity in Model Organisms

Ludwig-Maximilians-Universität München
2025

LMU Klinikum
2025

Shenzhen Stock Exchange
2024

East China Normal University
2021-2024

China Meteorological Administration
2021-2024

Brigham and Women's Hospital
2024

Zhejiang Chinese Medical University
2024

Tianjin Medical University
2006-2023

Second Hospital of Tianjin Medical University
2023

Simon Fraser University
2010-2022

Monocyte chemotactic protein-1 (MCP-1) plays a key role in the recruitment and activation of monocytes during inflammation. Increased MCP-1 serum levels patients with various cancers were correlated advanced stage. Here, we evaluated on prostate cancer (CaP) cell proliferation invasion.Expression tissue specimens was analyzed by immunohistochemical staining. production determined ELISA conditioned media collected from primary epithelia (PrEC), LNCaP, C4-2B, PC3 cells, hFOB. Cell invasion...

10.1002/pros.20464 article EN The Prostate 2006-01-01

10.1016/0031-3203(94)00068-w article EN Pattern Recognition 1995-01-01

While the roles of mammalian target rapamycin (mTOR) signaling in regulation cell growth, proliferation, and survival have been well documented various types, its actions osteoblasts are poorly understood. In this study, we determined effects rapamycin, a specific inhibitor mTOR, on osteoblast proliferation differentiation using MC3T3-E1 preosteoblastic cells (MC-4) primary mouse bone marrow stromal (BMSCs). Rapamycin significantly inhibited both MC-4 BMSCs at concentration as low 0.1 nM....

10.1002/jcb.21411 article EN Journal of Cellular Biochemistry 2007-05-21

Pharmacological induction of NRF2 restores redox homeostasis and slows cystogenesis in mouse models polycystic kidney disease.

10.1126/scitranslmed.aba3613 article EN Science Translational Medicine 2020-07-29

Adeno-associated virus (AAV)-based vectors have emerged as an effective and widely used technology for somatic gene therapy approaches, including those targeting the retina. A major advantage of AAV is availability a large number serotypes that either been isolated from nature or produced in laboratory. These different properties terms sensitivity to neutralizing antibodies, cellular transduction profile efficiency. The infectivity depends on affinity certain molecules cell surface,...

10.1016/j.ejps.2025.107012 article EN cc-by-nc European Journal of Pharmaceutical Sciences 2025-01-01

10.1016/0031-3203(95)00072-0 article EN Pattern Recognition 1996-01-01

Response styles are frequently of concern when rating scales used in psychological survey instruments. While latent trait models provide an attractive way controlling for response style effects (Morren, Gelissen, & Vermunt, 2011), the analyses generally limited to accommodating only a small number types. The use anchoring vignettes provides opportunity overcome this limitation. In article, new model is introduced that uses vignette responses measure and control any form style. An...

10.1037/met0000016 article EN Psychological Methods 2014-01-01

An analysis is presented of the behavior edges in scale space for deriving rules useful reasoning. This liner at different scales images includes mutual influence and identifies what neighboring start influencing response a Laplacian or Gaussian operator. Dislocation edges, false merging are examined to formulate reasoning space. The theorems, corollaries, assertions can be used recover related features, complex images. results reported include one lemma, three number corollaries six...

10.1109/34.19032 article EN IEEE Transactions on Pattern Analysis and Machine Intelligence 1989-04-01

Background: Anaplastic thyroid carcinoma (ATC) is one of the most aggressive malignancies, with no effective treatment currently available. The molecular mechanisms ATC carcinogenesis remain poorly understood. objective this study was to investigate and functions super-enhancer (SE)-driven oncogenic transcriptional addiction in progression identify new drug targets for treatments. Methods: High-throughput chemical screening performed drugs inhibiting cell growth. Cell viability assay, colony...

10.1089/thy.2018.0550 article EN Thyroid 2019-03-29

10.1016/s0031-3203(01)00050-4 article EN Pattern Recognition 2002-02-01

P-TEFb activation by cAMP-PKA signaling promotes cystogenic gene transcription elongation and disease progression in ADPKD.

10.1126/sciadv.aaw3593 article EN cc-by-nc Science Advances 2019-06-01

A high squint subaperture (HSS) algorithm was developed from the perspective of a strip map synthetic aperture radar (SAR) system and has ability to focus SAR data at extremely angle 55/spl deg/ with less than 1.27% mainlobe expansion or even higher angles if larger can be tolerated. The unique characteristic this is that subapertures are formed by multiplying received signal set overlapped complex conjugated reference signals where chirp rate varies in azimuth direction. This done solve...

10.1109/36.921413 article EN IEEE Transactions on Geoscience and Remote Sensing 2001-05-01

Explores the role of reasoning in early vision processing. In particular, problem detecting edges is addressed. The authors do not try to develop another edge detector, but rather, they study an detector rigorously understand its behavior well enough formulate a process that allow appliance judiciously recover useful information. They present multiscale algorithm for recovery: about scale space (RESS). knowledge RESS acquired from theory and represented by number procedures. recovers desired...

10.1109/34.126806 article EN IEEE Transactions on Pattern Analysis and Machine Intelligence 1992-04-01

10.1016/j.insmatheco.2005.05.006 article EN Insurance Mathematics and Economics 2005-07-13

An approach and strategy for automatic detection of buildings from aerial images using combined image analysis interpretation techniques is described in this paper. It undertaken several steps. A dense DSM obtained by stereo matching then the results multi-band classification, DSM, Normalized Difference Vegetation Index (NDVI) are used to reveal preliminary building interest areas. From these areas, a shape modeling algorithm has been precisely delineate their boundaries. The Dempster-Shafer...

10.14358/pers.72.4.395 article EN cc-by-nc-nd Photogrammetric Engineering & Remote Sensing 2006-04-01

Abstract In this paper we derive some results on the dividend payments prior to ruin in a Markovmodulated risk process which rate for Poisson claim arrival and distribution of sizes vary time depending state an underlying (external) Markov jump {J(t); t ≥ 0}. The main feature model is flexibility modeling sense that periods with very frequent arrivals few may alternate, states 0} could describe, example, epidemic types health insurance or weather conditions car insurance. A system...

10.1080/10920277.2007.10597448 article EN North American Actuarial Journal 2007-04-01

10.1007/bf00117809 article EN Applied Intelligence 1996-04-01

10.1016/j.stamet.2004.10.004 article EN Statistical Methodology 2004-12-10

10.1016/j.insmatheco.2008.04.004 article EN Insurance Mathematics and Economics 2008-05-05

In this paper, we consider a two-level multidimensional item response model that examines country differences in extreme style (ERS) as possible cause for the achievement-attitude paradox PISA 2006. The is an extension of Bolt & Newton (2011) uses data from seven attitudinal scales to assess and control its effects estimating correlations between attitudes achievement. Despite detectable variability ERS across countries biasing on scores, our results suggest unexpected between-country...

10.1186/s40536-015-0012-0 article EN cc-by Large-scale Assessments in Education 2015-08-17
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