Inge A. M. van Erp
- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Trauma and Emergency Care Studies
- Cardiac Arrest and Resuscitation
- Abdominal Trauma and Injuries
- Sepsis Diagnosis and Treatment
- Pelvic and Acetabular Injuries
- Intracerebral and Subarachnoid Hemorrhage Research
- Spinal Fractures and Fixation Techniques
- Neonatal and fetal brain pathology
- Cerebrospinal fluid and hydrocephalus
- Resilience and Mental Health
- Trauma Management and Diagnosis
- Posttraumatic Stress Disorder Research
- Pharmaceutical studies and practices
- Palliative Care and End-of-Life Issues
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Hemophilia Treatment and Research
- S100 Proteins and Annexins
- Neurosurgical Procedures and Complications
Medisch Centrum Haaglanden
2021-2025
Leiden University Medical Center
2021-2025
Massachusetts General Hospital
2020-2022
Limited evidence existed on the comparative effectiveness of decompressive craniectomy (DC) versus craniotomy for evacuation traumatic acute subdural hematoma (ASDH) until recently published randomised clinical trial RESCUE-ASDH. In this study, that ran concurrently, we aimed to determine current practice patterns and compare outcomes primary DC craniotomy.We conducted an analysis centre treatment preference within prospective, multicentre, observational Collaborative European NeuroTrauma...
OBJECTIVE The aim of this study was to compare the outcomes early (≤ 90 days) and delayed (> cranioplasty following decompressive craniectomy (DC) in patients with traumatic brain injury (TBI). METHODS authors analyzed participants enrolled Collaborative European NeuroTrauma Effectiveness Research Traumatic Brain Injury (CENTER-TBI) Neurotraumatology Quality Registry (Net-QuRe) studies who were diagnosed TBI underwent DC subsequent cranioplasty. These prospective, multicenter,...
Evidence regarding the effect of surgery in traumatic intracerebral hematoma (t-ICH) is limited and relies on STITCH(Trauma) trial. This study aimed at comparing effectiveness early to conservative treatment patients with a t-ICH.In prospective cohort, we included large t-ICH (< 48 h injury). Primary outcome was Glasgow Outcome Scale Extended (GOSE) 6 months, analyzed multivariable proportional odds logistic regression. Subgroups injury severity isolated vs. non-isolated t-ICH.A total 367...
Treatment-limiting decisions (TLDs) can be inevitable severe traumatic brain injury (s-TBI) patients, but data on their use remain scarce. To investigate the prevalence, timing and considerations of TLDs in s-TBI patients. patients between 2008 2017 were analysed retrospecively. Patient data, timing, location, involvement proxies, reasons for collected. Baseline characteristics in-hospital outcomes compared with without TLDs. reported 117 270 (43.3%) 95.9% deaths after preceded by a TLD. The...
Abstract Background Traumatic brain injury (TBI) is a major cause of death and disability across all ages. After the primary impact, pathophysiologic process secondary consists neuroinflammation response that critically leads to irreversible damage in first days after trauma. A key catalyst this inflammatory complement system. Inhibiting system could therefore be therapeutic target TBI. Objective To study safety efficacy C1-inhibitor (C1-INH) compared placebo patients with By temporarily...