Ranjit D. Singh
A5056764200- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Trauma and Emergency Care Studies
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Spinal Fractures and Fixation Techniques
- Cardiac Arrest and Resuscitation
- Neurosurgical Procedures and Complications
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- Sepsis Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Cerebrospinal fluid and hydrocephalus
- Acute Ischemic Stroke Management
- Frailty in Older Adults
- Cardiac Imaging and Diagnostics
- Radiation Dose and Imaging
- Resilience and Mental Health
- S100 Proteins and Annexins
- Vascular Malformations Diagnosis and Treatment
- Posttraumatic Stress Disorder Research
- Venous Thromboembolism Diagnosis and Management
- Autopsy Techniques and Outcomes
- Hip and Femur Fractures
Medisch Centrum Haaglanden
2021-2025
Leiden University Medical Center
2022-2025
Leiden University
2022-2024
Addenbrooke's Hospital
2022-2024
University of Cambridge
2022-2024
Stiftung Liebenau (Germany)
2022
Integra LifeSciences (United States)
2022
Hutchinson (United Kingdom)
2022
KU Leuven
2022
University of Liverpool
2021-2022
Limited evidence existed on the comparative effectiveness of decompressive craniectomy (DC) versus craniotomy for evacuation traumatic acute subdural hematoma (ASDH) until recently published randomised clinical trial RESCUE-ASDH. In this study, that ran concurrently, we aimed to determine current practice patterns and compare outcomes primary DC craniotomy.We conducted an analysis centre treatment preference within prospective, multicentre, observational Collaborative European NeuroTrauma...
OBJECTIVE The aim of this study was to compare the outcomes early (≤ 90 days) and delayed (> cranioplasty following decompressive craniectomy (DC) in patients with traumatic brain injury (TBI). METHODS authors analyzed participants enrolled Collaborative European NeuroTrauma Effectiveness Research Traumatic Brain Injury (CENTER-TBI) Neurotraumatology Quality Registry (Net-QuRe) studies who were diagnosed TBI underwent DC subsequent cranioplasty. These prospective, multicenter,...
BackgroundEven patients with normal computed tomography (CT) head imaging may experience persistent symptoms for months to years after mild traumatic brain injury (mTBI). There is currently no good way predict recovery and triage who benefit from early follow-up targeted intervention. We aimed assess if existing prognostic models can be improved by serum biomarkers or diffusion tensor metrics (DTI) MRI, identify DTI.MethodsWe included 1025 aged >18 a Glasgow Coma Score >12 CT the...
In patients with anterior circulation aneurysmal Subarachnoid Haemorrhage (aSAH), endovascular coiling is currently practiced more frequently than neurosurgical clipping. However, despite multiple previous studies, it still uncertain whether favourable in terms of long-term clinical outcome.
Evidence regarding the effect of surgery in traumatic intracerebral hematoma (t-ICH) is limited and relies on STITCH(Trauma) trial. This study aimed at comparing effectiveness early to conservative treatment patients with a t-ICH.In prospective cohort, we included large t-ICH (< 48 h injury). Primary outcome was Glasgow Outcome Scale Extended (GOSE) 6 months, analyzed multivariable proportional odds logistic regression. Subgroups injury severity isolated vs. non-isolated t-ICH.A total 367...
Acute subdural hematoma (ASDH) due to traumatic brain injury (TBI) constitutes an increasing global health problem, especially in the elderly population. Treatment decisions on surgical versus conservative management pose a neurosurgical dilemma. Large practice variation exists between countries, hospitals, and individual neurosurgeons, illustrating presence of 'clinical equipoise'. The RESET-ASDH trial aimed address this dilemma but was terminated prematurely insufficient patient recruitment.
Abstract Background The rapidly increasing number of elderly (≥ 65 years old) with TBI is accompanied by substantial medical and economic consequences. An ASDH the most common injury in surgical versus conservative treatment this patient group remains an important clinical dilemma. Current BTF guidelines are not based on high-quality evidence compliance low, allowing for large international variation. RESET-ASDH trial multicenter RCT (cost-)effectiveness early neurosurgical hematoma...
Abstract Repeated mild traumatic brain injury is of growing interest regarding public and sporting safety thought to have greater adverse or cumulative neurological effects when compared with single injury. While epidemiological links between repeated outcome been investigated in humans, exploration its mechanistic substrates has largely undertaken animal models. We acute repeat (n = 21) that healthy controls 76) using resting-state functional MRI quantified thalamic connectivity, given...
BACKGROUND White cord syndrome is an extremely rare complication of cervical decompressive surgery, characterized by serious postoperative neurological deficits in the absence apparent surgical complications. It named after characteristic ischemic-edematous intramedullary T2-hyperintense signal on magnetic resonance imaging and believed to be caused ischemic-reperfusion injury. Neurological typically manifest immediately delayed occurrence has been reported only once. OBSERVATIONS The...
Traumatic brain injury (TBI) is a major global health problem that disproportionally affects low- and middle-income countries. The needs for patients with TBI therefore may differ between levels of national development. We aimed to describe differences in epidemiology acute care provision India Europe.
In 1960, Lazorthes and Campman introduced the concept of a