A5008524773- Nutritional Studies and Diet
- Trace Elements in Health
- Heavy metals in environment
- Nutrition and Health in Aging
- Adsorption and biosorption for pollutant removal
- Phosphorus and nutrient management
- Diet and metabolism studies
- Mine drainage and remediation techniques
- Heavy Metal Exposure and Toxicity
- Antioxidant Activity and Oxidative Stress
- Bone health and osteoporosis research
- Folate and B Vitamins Research
- Electrokinetic Soil Remediation Techniques
- Iron Metabolism and Disorders
- Vitamin D Research Studies
- Metal Extraction and Bioleaching
- Body Composition Measurement Techniques
- Chromium effects and bioremediation
- Wastewater Treatment and Nitrogen Removal
- Consumer Attitudes and Food Labeling
- Biochemical Analysis and Sensing Techniques
- Vitamin C and Antioxidants Research
- Olfactory and Sensory Function Studies
- Muscle metabolism and nutrition
- Health Systems, Economic Evaluations, Quality of Life
Centre de Recherche en Nutrition Humaine d'Auvergne
2012-2025
Centre Hospitalier Universitaire de Clermont-Ferrand
2013-2025
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2014-2022
Virologie et Immunologie Moléculaires
2022
Unité de Nutrition Humaine
2008-2020
Centre de Recherche en Nutrition Humaine Rhône-Alpes
2005-2018
Université Clermont Auvergne
2013-2014
Unité de recherche sur les maladies cardiovasculaires et métaboliques
2005-2013
Institut National de la Recherche Scientifique
1994-2011
Institut National de la Recherche Agronomique
2000-2008
Objective Ageing is accompanied by deterioration of multiple bodily functions and inflammation, which collectively contribute to frailty. We others have shown that frailty co-varies with alterations in the gut microbiota a manner accelerated consumption restricted diversity diet. The Mediterranean diet (MedDiet) associated health. In NU-AGE project, we investigated if 1-year MedDiet intervention could alter reduce Design profiled 612 non-frail or pre-frail subjects across five European...
We aimed to determine the effect of a Mediterranean-style diet, tailored meet dietary recommendations for older adults, on blood pressure and arterial stiffness. In 12 months, randomized controlled trial (NU-AGE [New Dietary Strategies Addressing Specific Needs Elderly Population Healthy Aging in Europe]), was measured 1294 healthy participants, aged 65 79 years, recruited from 5 European centers, stiffness subset 225 participants. The intervention group received individually standardized...
BACKGROUND―Findings from animal and epidemiological research support the potential neuroprotective benefits healthy diets. However, to establish diet-neuroprotective causal relations, evidence dietary intervention studies is needed. NU-AGE first multicenter assessing whether a diet targeting health in aging can counteract age-related physiological changes different organs, including brain. In this study, we specifically investigated effects of NU-AGE's on cognitive decline. MATERIALS AND...
Background: Nutrition-related knowledge (NRK) and nutrition-related attitudes (NRAs) are necessary for dietary changes toward healthier patterns. In turn, patterns can be beneficial in maintaining health of older adults. Therefore, the aim this cross-sectional study was to investigate whether NRK NRAs were associated with lifestyle features among adults (65+ years) from five European countries (France, Italy, Poland, Netherlands United Kingdom). Methods: Within project NU-AGE, 1,144 healthy...
Intensive industrialization generates hazardous wastes comprising organics, inorganics, heavy metals, and munitions that need to be tackled in a safe manner. Commonly employed physicochemical technologies have paved the way ecofriendly bioremediation processes. Bioremediation uses natural as well recombinant microorganisms break down toxic substances by aerobic anaerobic means. They can applied on site (in situ) or off (ex situ), mediated mixed microbial consortia and/or pure strains and....
Lutein is recovered at high concentration in the human macula lutea. Recent studies suggest that this micronutrient might be implicated prevention of age-related macular degeneration.to identify genes which affect blood and retina lutein concentrations among candidate (intestinal sterol transporters carotenoid oxygenases).a comparative plus an observational study.twenty-nine healthy subjects for study 622 study.all participants were genotyped single nucleotide polymorphisms (SNPs) genes....
The Mediterranean diet (MD) is widely recommended for the prevention of chronic disease, but evidence a beneficial effect on bone health lacking. aim this study was to examine Mediterranean-like dietary pattern [NU-AGE (New Dietary Strategies Addressing Specific Needs Elderly Population Healthy Aging in Europe)] indexes inflammation with number secondary endpoints, including mineral density (BMD) and biomarkers collagen degradation 1-y multicenter randomized controlled trial (RCT; NU-AGE)...
Abstract Heavy metals in acidic leachates from sewage sludge are usually removed by chemical precipitation, which often requires high concentration of chemicals and induces metallic production. Electrochemical technique has been explored as an alternative method a laboratory pilot scale reactor for heavy (Cu Zn) removal leachate. Three electrolytic cell arrangements using different electrodes materials were tested: mild steel or aluminium bipolar electrode (EC cell), Graphite/stainless...
The aim of this work was to examine the cross-sectional relationship between body composition (BC) markers for adipose and lean tissue bone mass, a wide range specific inflammatory adipose-related in healthy elderly Europeans.A whole-body dual-energy X-ray absorptiometry (DXA) scan made 1121 (65-79 years) women men from five European countries "New dietary strategies addressing needs population aging Europe" project (NCT01754012) cohort measure mass. Pro-inflammatory (IL-6, IL-6Rα, TNF-α,...
Inflammation mediates several chronic diseases. Micronutrients can act on inflammation, either through modulating cytokine production or by scavenging by-products of activated white cells. Identifying dietary patterns (DP) reflecting these mechanisms and relating them to inflammation is interest. The objective the study was identify DP specifically associated with intakes nutrients potentially involved in inflammatory processes a middle-aged population investigate long-term associations...
Recent advances in the study of gut microbiota has pointed to its under-utilized source potentially beneficial bacteria, known as next generation probiotics, offering a promising avenue restore or compensate impaired toward healthy state. Aside from difficulties achieve in-lab adequate culture conditions, use bacterial isolates is also limited by their bioavailability donor itself. In iTARGET study, we positively selected donors based on diet enriched fiber, that been shown increase...
Body composition (BC) is an emerging important factor for the characterization of metabolic status. The assessment BC has been studied in various populations and diseases such as obesity, diabetes, endocrine well physiological paraphysiological conditions growth aging processes, physical training. A gold standard technique human at molecular level represented by dual-energy X-ray absorptiometry (DXA), which able to precisely assess measure body mass (and areal bone mineral density-aBMD) on a...
Collagen proteins are crucial components of the bone matrix. Since collagen-derived products widely used in food and supplement industry, one may raise question whether collagen-enriched diets can provide benefits for skeleton. In this study, we designed an innovative approach to investigate taking into account metabolites that formed by digestive tract appear circulation after ingestion hydrolysed collagen. Blood samples collected clinical pre-clinical trials following absorption collagen...
Abstract Background There are several mechanisms via which increased protein intake might maintain or improve bone mineral density (BMD), but current evidence for an association effect is inconclusive. The objectives of this study were to investigate the between dietary (total, plant and animal) with BMD (spine total body) effects supplementation on BMD. Methods Individual data from four trials that included either (pre‐)frail, undernourished healthy older adults (aged ≥65 years) combined....