A5100347837- Gastric Cancer Management and Outcomes
- Cancer, Lipids, and Metabolism
- Cancer, Hypoxia, and Metabolism
- Intracranial Aneurysms: Treatment and Complications
- Gastrointestinal Tumor Research and Treatment
- Cancer-related molecular mechanisms research
- Esophageal Cancer Research and Treatment
- S100 Proteins and Annexins
- MRI in cancer diagnosis
- Alcoholism and Thiamine Deficiency
- Seismology and Earthquake Studies
- Infant Nutrition and Health
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- HER2/EGFR in Cancer Research
- Advanced Glycation End Products research
- Oral Health Pathology and Treatment
- Peroxisome Proliferator-Activated Receptors
- Diet and metabolism studies
- Pleural and Pulmonary Diseases
- Metabolism, Diabetes, and Cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pneumothorax, Barotrauma, Emphysema
- Medical Imaging and Analysis
- Breastfeeding Practices and Influences
Chinese Center For Disease Control and Prevention
2025
Visby lasarett
2025
University Medical Center Utrecht
2025
KU Leuven
2024
VIB-KU Leuven Center for Cancer Biology
2024
Southern Medical University
2014-2023
Nanfang Hospital
2020-2022
Guangzhou Regenerative Medicine and Health Guangdong Laboratory
2022
Lishui City People's Hospital
2022
Shanghai Pulmonary Hospital
2021
Improving the rate of polyp detection is an important measure to prevent colorectal cancer (CRC). Real-time automatic systems, through deep learning methods, can learn and perform specific endoscopic tasks previously performed by endoscopists. The purpose this study was explore whether a high-performance, real-time system could improve (PDR) in actual clinical environment.
Amplification of chromosome 7p11 (7p11) is the most common alteration in primary glioblastoma (GBM), resulting gains epidermal growth factor receptor ( EGFR ) copy number 50 to 60% GBM tumors. However, treatment strategies targeting have thus far failed clinical trials, and underlying mechanism remains largely unclear. We here demonstrate that amplification at locus frequently encompasses its neighboring genes identifies SEC61G as a critical regulator facilitating immune evasion tumor...
Accumulating evidence suggests that activation of mitogen-activated protein kinases (MAPKs) and nuclear factor NF-κB exacerbates early brain injury (EBI) following subarachnoid hemorrhage (SAH) by provoking proapoptotic proinflammatory cellular signaling. Here we evaluate the role TGFβ-activated kinase 1 (TAK1), a critical regulator MAPK pathways, in SAH. Although expression level TAK1 did not present significant alternation basal temporal lobe after SAH, phosphorylated (Thr-187, p-TAK1)...
Abstract Background/Introduction It is increasingly recognized that the built environment plays an important role in development of cardiovascular diseases (CVD). The evidence on relationship between neighbourhood walkability, a environmental construct, and CVD limited, largely relies cross-sectional studies. Purpose To investigate changes residential walkability incidence adults. Methods Using data from Statistics Netherlands, we included all Dutch residents aged 40 years or older at...
Previous studies have reported inconsistent associations between serum vitamin D levels and bacterial vaginosis (BV). Therefore, this study aimed to comprehensively investigate the relationship concentrations BV risk among adult women in United States. Data from National Health Nutrition Examination Survey (NHANES) 2001-2004 were analyzed. Multivariate logistic regression was used assess association BV. Additionally, smoothing curve fitting subgroup analyses performed explore potential...
The association between dietary thiamine intake and the risk of diabetes remains unknown.We aimed to evaluate relation with new-onset examine possible effect modifiers.Prospective cohort study.A total 16 272 participants who were free at baseline enrolled from China Health Nutrition Survey (CHNS). Dietary nutrients information was collected by 3-day recalls in addition using a food-weighed method assess cooking oil condiment consumption. New-onset defined as fasting blood glucose ≥7.0 mmol/l...
Cucurbitacin B, a triterpenoid compound found in many Cucurbitaceae species, possesses significant antioxidant and anti-inflammatory activity. This research aims to determine the effects of B experimental periodontitis model. Experimental were induced Sprague Dawley rats by ligature method. Silk suture (4/0) was ligated subgingivally around mandibular right first molars placed position for 11 days. The treatment group animals administered (12.5 mg, 25 50 mg/kg bwt) via oral gavage 12 days...
Overproduction of reactive oxygen species (ROS) and aberrant lipid metabolism are established hallmarks cancer; however, the role ROS in synthesis during tumorigenesis is almost unknown. Herein, we show that regulates thus controls colorectal through a p53-dependent mechanism. In p53 wild-type cancer (CRC) cells, hydrogen peroxide (H2O2)-induced expression represses transcription deubiquitinase USP22, which otherwise deubiquitinates stabilizes Fatty Acid Synthase (FASN), inhibits fatty acid...
Artificial Intelligence (AI) has permeated numerous aspects of our daily lives, from predictive text on smartphones to complex decision-making systems in healthcare and finance. While AI shown remarkable accuracy efficiency, it is often criticized for being a 'black box,' particularly when comes models like deep learning large language (LLMs). This where Explainable (XAI) into play.Explainable aims make decisions transparent, understandable, interpretable. The lack interpretability raised...
To investigate the HER2/c-erbB-2, epidermal growth factor receptor (EGFR) protein expression in gastric cancer and association with patients' clinical pathology characteristics prognosis.HER2/c-erbB-2 EGFR was examined by immunohistochemical assay tissue corresponding paired normal of 67 patients carcinoma. The positive rate were compared. correlation between survival evaluated.The HER2/c-erbB-2 tissues 32.8% (22/67) 4.5% (3/67), respectively statistical difference (p<0.05). And 41.8%...
Most gastric cancer and gastroesophageal junction carcinoma (GEJ) patients are already in the advanced stage at time of diagnosis.Thus, probability radical gastrectomy is low, surgical treatment alone has a poor prognosis due to high recurrence rate.In order reduce distant metastasis after surgery, there have been many attempts made improve perioperative localized cancer, but no uniform criteria exist.Over recent years, immunotherapy revolutionized treatment, immune checkpoint inhibitors...
To overcome difficulties in the removal of duodenal bulb lesions, especially those anatomically challenging locations, we developed endoscopic resection via antral submucosal tunneling (ERAST) technique. In this study, evaluated feasibility and safety ERAST for superficial subepithelial lesions bulb. This was a single-center retrospective study 10 patients with Submucosal from gastric antrum to duodenum performed facilitate en bloc tumor The rate, postoperative bleeding, perforation were...
Objective To evaluate the impacts of two different gastrectomy methods on quality life, complication and prognosis in proximal gastric cancer. Methods One hundred cases cancer Tung Wah Hospital were collected for retrospective analysis. They divided into gastrectomy/gastroesophagostomy (PG) group (n=50) total gastrectomy/esophagojejunostomy (TG) (n=52), according to reconstruction. The postoperative complications, nutritional status groups compared. Results The incidence reflux...
Objective To determine the expression of microRNA (miRNA, miR)-28-3p in giant cell tumor bone and its effect on neoplasm biological behaviors. Methods The samples including adjacent normal tissues from 20 patients with were harvested. Real-time quantitative polymerase chain reaction (Real-time PCR) Taqman probe technique fluorescence situ hybridization applied to ascertain miR-28-3p tissue tissues. Primary stromal cells (GCTSCs) used as target transfected bionic agent inhibitor,...
Objective To analyze the effect of tumor number on survival patients with colorectal liver metastases(CRLM) undergoing hepatic resection and definition oligometastases. Methods Clinicopathological data liver-only metastases from our database were retrospectively analyzed. Results Of all 377 patients, median was 2. The 5-year disease free rate 24.1%. overall 39.8%. Survival oligometastatic not significantly different non-oligometastatic patients(χ2=3.037, P=0.081). 6-10 tumors...