A5063623034- Osteoarthritis Treatment and Mechanisms
- Facial Rejuvenation and Surgery Techniques
- Facial Nerve Paralysis Treatment and Research
- Mesenchymal stem cell research
- Reconstructive Facial Surgery Techniques
- Reconstructive Surgery and Microvascular Techniques
- Forest ecology and management
- Periodontal Regeneration and Treatments
- Dermatologic Treatments and Research
- Bone fractures and treatments
- Botulinum Toxin and Related Neurological Disorders
- Nasal Surgery and Airway Studies
- Nail Diseases and Treatments
- Plant Pathogens and Fungal Diseases
- Congenital Diaphragmatic Hernia Studies
- Food Quality and Safety Studies
- Skin Protection and Aging
- Genomics, phytochemicals, and oxidative stress
- Immune cells in cancer
- Cancer Mechanisms and Therapy
- Aluminum Alloys Composites Properties
- Bioactive Compounds and Antitumor Agents
- Ear Surgery and Otitis Media
- Plant biochemistry and biosynthesis
- Respiratory Support and Mechanisms
Huadong Hospital
2013-2025
Fudan University
2013-2025
Wuhan University of Technology
2008-2025
Tiangong University
2024
South China Agricultural University
2009-2024
Chinese PLA General Hospital
2017-2024
Chongqing Medical University
2024
Dalian Maternal and Child Health Hospital
2024
Shanghai Medical College of Fudan University
2024
China Agricultural University
2023-2024
Treatment of severe Coronavirus Disease 2019 (COVID-19) is challenging. We performed a phase 2 trial to assess the efficacy and safety human umbilical cord-mesenchymal stem cells (UC-MSCs) treat COVID-19 patients with lung damage, based on our 1 data. In this randomized, double-blind, placebo-controlled trial, we recruited 101 damage. They were randomly assigned at 2:1 ratio receive either UC-MSCs (4 × 10
In this study, a soy protein isolate (SPI)-pectin (PC) complex was prepared, and the effects of different high intensity ultrasound (HIU) powers on structure solubility were studied. Fourier transform infrared (FTIR) spectroscopy analysis exhibited that with increasing HIU power, α-helix content SPI in significantly reduced, random coil increased; however, an opposite trend appeared after higher power treatments. Fluorescence spectra showed treatment increased fluorescence complex, surface...
In vivo niche is known to play important roles in terminal differentiation of implanted bone marrow stromal cells (BMSCs). This study explored the feasibility repairing articular osteochondral defects using autologous BMSCs and biodegradable polymers. from 18 hybrid pigs' marrows were either treated with dexamethasone (40 ng/mL) alone or chondrogenically induced transforming growth factor-β1 (10 ng/mL). The seeded respectively onto polylactic acid (PLA)- coated polyglycolic (PGA) scaffolds....
Kittens are prone to intestinal health problems as their intestines not completely developed. Seaweed is rich in plant polysaccharides and bioactive substances that highly beneficial gut health. However, the effects of seaweed on cat have been assessed. This study compared dietary supplementation with enzymolysis powder Saccharomyces boulardii kittens. In total, 30 Ragdoll kittens (age: 6 months; weight: 1.50 ± 0.29 kg) were assigned three treatment groups for a 4-week feeding trial. The...
Ultraviolet B (UVB) irradiation alters multiple molecular pathways in the skin, thereby inducing skin photoaging. Murine dermal fibroblasts (MDFs) were subjected to a series of 4 sub-cytotoxic UVB doses (120 mJ/cm2), resulting changes cell shape, DNA damage, cycle arrest, extracellular matrix variations, reactive oxygen species (ROS) generation, and alterations major intracellular antioxidant cellular autophagy levels. Rapamycin (RAPA) is new macrolide immunosuppressive agent that primarily...
Abstract A novel structural wall pipe, PVC axial hollow‐wall pipe (AHWP) has been developed to reduce carbon emissions during the “Full Life Cycle” of pipelines by reducing material use in walls. The advantages and application prospects AHWP are examined, followed manufacturing prototypes using advanced production techniques. properties, internal external pressure resistance, impact buried load deformation three types were evaluated. Experimental numerical simulations analyzed how...
Ingrown nails may cause progressively aggravated pain, discomfort and immobility. We modified the traditional Winograd procedure proposed an improved surgical method which is ship-shaped resection along with nail matrix destruction. evaluate clinical outcome of this approach, especially in terms recurrence healing time as well aesthetical outcomes. retrospectively analyzed outcomes 200 consecutive patients grade II/III ingrown toenails were operated using from November 2020 to 2022....
Background Cystic fibrosis (CF) is caused by CFTR gene mutations. Its diagnosis mainly depends on genetic and sweat chloride tests, but the complexity of these mutations challenges diagnosis. Methods This paper reports a new case Chinese child with cough wheezing, suspected having CF. Trio whole-exome sequencing for pedigree was carried out to detect Five tools, namely Mutation Taster, PolyPhen-2, SIFT, FATHMM, PROVEAN, were used predict impacts protein function. AlphaFold employed...
Hepatocellular carcinoma (HCC) is an aggressive tumor with a poor prognosis that highly expresses phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (ERK). The PI3K/AKT/mTOR MAPK/ERK signaling pathways play crucial role in HCC formation, cell cycle, apoptosis survival. However, no effective targeted therapies against these available, mainly due to the extensive complex negative feedback loops between them. Here we used CK-3, dual blocker of pathways, lines verify its...
Effect of polyols (mannitol, sorbitol, and xylitol) at three concentrations (5, 10, 15% w/w) on the structure soy protein isolates (SPI) was investigated. Changes in foaming properties SPI were then examined with addition different concentrations. The interactions between resulted a substantial decrease surface hydrophobicity intrinsic tryptophan fluorescence intensity, along covering tyrosine. Furthermore, circular dichroism (CD) spectroscopy suggested that more ordered compact conformation...
Total scalp avulsion is an intractable problem in clinical practice. It often occurs female adults, but rarely children. In this article, we described the replantation of 2 segments a 4-year-old girl. The right segment involved hairy merely, whereas left one scalp, forehead, eyelid, ear, and part face. Warm ischemia time was about 28 hours, operation 13 hours. Although explorative performed, survived partly. A relatively satisfactory aesthetic result obtained by transplanting split skin from...
Some patients experience massive neglected scalp malignant tumors involving the soft tissues and bone. Management of these includes thorough tissue resection to obtain negative margins cover defects with enough composite tissues. In this article, we presented our experiences reconstructions free anterolateral thigh (ALT) flaps.We performed a retrospective review 6 who had single-stage tumor removal free-tissue transfer over last 10 years. All were treated ALT flaps or without fascia lata...
Emodin (1,3,8-trihydroxy-6-methylanthraquinone), as an active ingredient in rhubarb roots and rhizomes, has been reported to possess various pharmacological properties including anti-tumor effects. Recent studies have confirmed that emodin inhibited cell proliferation induced apoptosis of cancer cells. However, the inhibitory effect on migration invasion melanoma cells its underlying mechanism are still unclear. In study, we observed impercipient effects B16F10 A375 with strong metastatic...