A5026667360- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- Multiple and Secondary Primary Cancers
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Surgical Treatments
- Esophageal and GI Pathology
- Education, Psychology, and Social Research
- Global Cancer Incidence and Screening
- Pancreatic and Hepatic Oncology Research
- Metastasis and carcinoma case studies
- Helicobacter pylori-related gastroenterology studies
- Gastrointestinal Tumor Research and Treatment
- Cancer Genomics and Diagnostics
- Cancer Risks and Factors
- Metabolism, Diabetes, and Cancer
- Colorectal Cancer Treatments and Studies
- Diverticular Disease and Complications
- Dysphagia Assessment and Management
- Mycobacterium research and diagnosis
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Colorectal and Anal Carcinomas
- Gastrointestinal disorders and treatments
- Gastrointestinal Bleeding Diagnosis and Treatment
Military University Hospital Prague
2016-2025
Charles University
2016-2025
Peking University Cancer Hospital
2019-2021
Technical University of Munich
2019-2021
Military University
2013-2021
Peking University
2019-2021
University Hospital Kralovske Vinohrady
2013-2019
Masaryk University
2009-2016
Genomac
2016
University Hospital Hradec Králové
2016
The European Society of Gastrointestinal Endoscopy and United Gastroenterology present a short list key performance measures for lower gastrointestinal endoscopy. We recommend that endoscopy services across Europe adopt the following seven measurement evaluation in daily practice at center endoscopist level: <b>1</b> Rate adequate bowel preparation (minimum standard 90 %); <b>2</b> Cecal intubation rate <b>3</b> Adenoma detection 25 <b>4 </b>Appropriate polypectomy technique 80 <b>5</b>...
Objective The incidence of colorectal cancer (CRC) declines among subjects aged 50 years and above. An opposite trend appears younger adults. In Europe, data on CRC adults are lacking. We therefore aimed to analyse European trends in mortality than years. Design Data age-related between 1990 2016 were retrieved from national regional registries. Trends analysed by Joinpoint regression expressed as annual percent change. Results 143.7 million people 20–49 20 countries. Of them, 187 918...
Population-based screening for early detection and treatment of colorectal cancer (CRC) precursor lesions, using evidence-based methods, can be effective in populations with a significant burden the disease provided services are high quality. Multidisciplinary, guidelines quality assurance CRC diagnosis have been developed by experts project co-financed European Union. The 450-page were published book format Commission 2010. They include 10 chapters over 250 recommendations, individually...
Gastrointestinal microbiota may be involved in Helicobacter pylori-associated gastric cancer development. The aim of this study was to explore the possible microbial mechanisms carcinogenesis and potential dysbiosis arising from H. pylori infection.Deep sequencing 16S ribosomal RNA gene used investigate alterations paired biopsies stool samples 58 subjects with successful 57 failed anti-H. treatment, relative 49 negative subjects.In positive subjects, richness Shannon indexes increased...
<h3>Objective</h3> To clarify the full range of benefits and adverse consequences <i>Helicobacter pylori</i> eradication as a strategy for gastric cancer prevention, community-based intervention trial was launched in Linqu County, China. <h3>Design</h3> A total 184 786 residents aged 25–54 years were enrolled this received <sup>13</sup>C-urea breath test. <i>H. positive participants assigned into two groups, either receiving 10-day quadruple anti-<i>H. treatment or lookalike placebos...
Eradication of Helicobacter pylori has been found to be effective for gastric cancer prevention, but uncertainties remain about the possible adverse consequences such as potential microbial dysbiosis. In our study, we investigated association between gut microbiota and H. pylori-related lesions in 47 subjects by deep sequencing 16S ribosomal RNA (rRNA) gene fecal samples. The dominant phyla samples were Bacteroidetes, Firmicutes Proteobacteria with average relative abundances 54.77%, 31.37%...
To develop standards for high quality in gastrointestinal (GI) endoscopy, the European Society of Gastrointestinal Endoscopy (ESGE) has established ESGE Quality Improvement Committee. A prerequisite assurance and improvement all GI endoscopy procedures is state-of-the-art integrated digital reporting systems standardized documentation procedures. The current paper describes ESGE's viewpoints on requirements high-quality endoscopy. <b>Recommendations</b> <b>1</b> must be electronic. <b>2</b>...
Capsule colonoscopy might present an alternative to for colorectal neoplasia screening. To assess the accuracy of second-generation capsule (CCE2) detection compared with conventional (CC). From 2011-2015, we performed a multicenter, prospective, cross-over study evaluating use CCE2 as possible cancer (CRC) screening test based on assessment method's characteristics (accuracy) and safety patient acceptance routine. Enrolled participants fulfilled CRC population criteria if they were...
We assessed the diagnostic performance of Narrow-Band Imaging (NBI) International Colorectal Endoscopic Classification (NICE) and Japan NBI Expert Team classification (JNET) in predicting histological outcomes advanced colorectal lesions. Additionally, we evaluated sensitivity positive predictive value (PPV) JNET NICE classifications individually for high-grade lesions (including HGD adenomas, intramucosal carcinomas, T1 carcinomas). This was a retrospective analysis prospectively collected...
Abstract Background Colectomy is the primary treatment for dysplastic lesions in inflammatory bowel disease (IBD). Since development of advanced endoscopic techniques, management dysplasia evolving. Endoscopic submucosal resection (ESD) could be used selected cases at referral centres as an alternative to colectomy. However, feasibility and safety IBD remains limited. Main aim: To evaluate en-bloc rate need colectomy due ESD failure IBD. Secondary aims: assess complications ESD, local...
The incidence and mortality of colorectal cancer (CRC) in the Czech Republic is significant. National CRC Screening Program started 2000 was further enhanced 2009. In 2010, European Guidelines were introduced. aim present trend study to evaluate quality Colorectal Cancer using early performance long-term impact indicators. screening program has been assessed data from three sources: Registry, Reference Centre, Registry. compared with a set recommended control Between 2006 total 1 881 299...
Objectives: The main objective is to compare the accuracy of EUS and CEH for diagnosis pancreatic cancer (PC). secondary evaluate FNA determine what extent findings are affected by endosonographer subjectivity.Methods: A prospective single-centre study was conducted in patients with lesions detected on CT. were examined EUS, FNA. obtained results compared final that based cytology further clinical histopathological from subjects who underwent surgery. second reading images performed...