A5013482530- COVID-19 epidemiological studies
- COVID-19 Pandemic Impacts
- Vaccine Coverage and Hesitancy
- Malaria Research and Control
- Female Genital Mutilation/Cutting Issues
- Global Maternal and Child Health
- COVID-19 and Mental Health
- Mosquito-borne diseases and control
- COVID-19 diagnosis using AI
- SARS-CoV-2 and COVID-19 Research
- Viral Infections and Outbreaks Research
- Urban and Rural Development Challenges
- Vibrio bacteria research studies
- Genital Health and Disease
- Complement system in diseases
- Epilepsy research and treatment
- Parasite Biology and Host Interactions
- Radiomics and Machine Learning in Medical Imaging
- COVID-19 Impact on Reproduction
- Healthcare Systems and Reforms
- Machine Learning in Bioinformatics
- Economic and Environmental Valuation
- Chronic Disease Management Strategies
- Feminism, Gender, and Sexuality Studies
- EEG and Brain-Computer Interfaces
University of Nairobi
2024-2025
Aga Khan University Nairobi
2025
African Population and Health Research Center
2022-2025
British Council
2020-2024
Kenya Medical Research Institute
2019-2021
University of California, San Diego
2020
Seattle University
2020
University of Washington
2020
Instituut voor Tropische Geneeskunde
2019
Africa Health Research Institute
2019
Abstract Background Many low- and middle-income countries have implemented control measures against coronavirus disease 2019 (COVID-19). However, it is not clear to what extent these explain the low numbers of recorded COVID-19 cases deaths in Africa. One main aims reduce respiratory pathogen transmission through direct contact with others. In this study, we collect data from residents informal settlements around Nairobi, Kenya, assess if changed patterns, estimate impact changes on basic...
Background: Urban slums are at high risk of COVID-19 transmission due to the lack basic housing, water, and sanitation facilities Overcrowded conditions mak
Objectives COVID-19 may spread rapidly in densely populated urban informal settlements. Kenya swiftly implemented mitigation policies; we assess the economic, social and health-related harm disproportionately impacting women. Design A prospective longitudinal cohort study with repeated mobile phone surveys April, May June 2020. Participants setting 2009 households across five settlements Nairobi, sampled from two previously interviewed cohorts. Primary secondary outcome measures Outcomes...
The government of Kenya has launched a phased rollout COVID-19 vaccination. A major barrier is vaccine hesitancy; the refusal or delay accepting This study evaluated level and determinants hesitancy in Kenya. We conducted cross-sectional administered through phone-based survey February 2021 four counties Multilevel logistic regression was used to identify individual perceived risks influences, context-specific factors vaccine-specific issues associated with hesitancy. high: 36.5%. Factors...
Objectives Approximately 80% of people with epilepsy live in low- and middle-income countries (LMICs), where limited resources stigma hinder accurate diagnosis treatment. Clinical machine learning models have demonstrated substantial promise supporting the diagnostic process LMICs by aiding preliminary screening detection possible cases without relying on specialised or trained personnel. How well these generalise to naïve regions is, however, underexplored. Here, we use a novel approach...
Measures to mitigate COVID-19's impact may inhibit development of healthy youth relationships, affecting partnership quality and sexual reproductive health (SRH) outcomes.
Natural killer (NK) cells are potent immune effectors that can be activated via antibody-mediated Fc receptor engagement. Using multiparameter flow cytometry, we found NK degranulate and release IFN-γ upon stimulation with antibody-opsonized
Many parts of Africa have witnessed reductions in Plasmodium falciparum transmission over the last 15 years. Since immunity to malaria is acquired more rapidly at higher transmission, slower acquisition lower may partially offset benefits transmission. We examined clinical spectrum disease and predictors mortality after sustained changes intensity, using data collected from 1989 2016. conducted a temporal observational analysis 18,000 children, aged 14 days years old, who were admitted...
Abstract Background Many low- and middle-income countries have implemented control measures against coronavirus disease 2019 (COVID-19). However, it is not clear to what extent these explain the low numbers of recorded COVID-19 cases deaths in Africa. One main aims reduce respiratory pathogen transmission through direct contact with others. In this study we collect data from residents informal settlements around Nairobi, Kenya assess if changed patterns, estimate impact changes on basic...
ABSTRACT The government of Kenya has launched a phased rollout COVID-19 vaccination. A major barrier is vaccine hesitancy; the refusal or delay accepting This study evaluated level and determinants hesitancy in Kenya. We conducted cross-sectional administered through phone-based survey February 2021 four counties Multivariate logistic regression was used to identify individual perceived risks influences, context-specific factors, vaccine-specific issues associated with hesitancy. high:...
Abstract Nairobi’s urban slums are ill equipped to prevent spread of the novel coronavirus disease (COVID-19) due high population density, multigenerational families in poorly ventilated informal housing, and poor sanitation. Physical distancing policies, curfews, a citywide lockdown were implemented March April 2020 resulting sharp decreases movement across city. However, most people cannot afford stay home completely (e.g., leaving daily fetch water). If still employed, they may need...
Background: Urban slums are at high risk of COVID-19 transmission due to the lack basic housing, water, and sanitation facilities. Overcrowded conditions make quarantine measures near impossible.Methods: A mobile phone knowledge, attitudes, practices survey was conducted March 30-31, 2020. Participants were sampled from two study cohorts across five urban in Nairobi, Kenya.Findings: 2,009 individuals (63% female) participated. Knowledge fever cough as symptoms high, but only 42% listed...
Community health workers (CHWs) play a critical role in supporting systems, and improving the availability accessibility to care. However, CHW programs globally continue face challenges with poor performance high levels of attrition. are often underfunded poorly planned, which can lead loss motivation by CHWs. The study aims determine preferences CHWs for job incentives goal furthering their success.Relevant incentive attributes were identified through focus group discussions in-depth...
<strong>Background:</strong> Integrated management of cardiometabolic diseases is crucial in improving the quality life older persons. The objective study was to identify clusters multimorbidity associated with moderate and severe disabilities Ghana South Africa. <strong>Methods:</strong> Data were from World Health Organization (WHO) on global AGEing adult health (SAGE) Wave-2 (2015) conducted We analysed clustering including angina, stroke, diabetes, obesity, hypertension unrelated...
Attrition is a challenge in parameter estimation both longitudinal and multi-stage cross-sectional studies. Here, we examine utility of machine learning to predict attrition identify associated factors two-stage population-based epilepsy prevalence study Nairobi. All individuals the Nairobi Urban Health Demographic Surveillance System (NUHDSS) (Korogocho Viwandani) were screened for two stages. was defined as probable cases identified at stage-I but who did not attend stage-II (neurologist...
<title>Abstract</title> Cardiometabolic diseases (CMDs) are major contributors to global morbidity and mortality, with significant disparities driven by socioeconomic factors. This study uses data collected in 2019 Kenya the AWI-Gen project, a collaborative initiative between University of Witwatersrand (Wits) INDEPTH Network. The work was conducted within Nairobi Urban Health Demographic Surveillance System (NUHDSS), run African Population Research Center (APHRC). main objective is apply...
Background Community health volunteers (CHVs) play crucial roles in enabling access to healthcare at the community levels. Although CHVs are considered volunteers, programmes provide financial and non-financial incentives. However, there is limited evidence on which bundle of incentives most effective for their improved performance. Methods We used a discrete choice experiment (DCE) understand incentive preferences with aim improve motivation, performance retention. Relevant attributes were...
Background: Uganda’s community health worker (CHW) program experiences several challenges related to the appropriate motivation, job satisfaction, and performance of CHW workforce. This study aims identify barriers in effective implementation financial non-financial incentives support CHWs strengthen program. Methods: The was implemented Lira, Wakiso, Mayuge districts May 2019. Ten focus group discussions (FGDs) were held with 91 CHWs, 17 in-depth interviews (IDIs) supervisors, 7 IDIs...
To illustrate the utility of unsupervised machine learning compared with traditional methods analysis by identifying archetypes within population that may be more or less likely to get COVID-19 vaccine.A longitudinal prospective cohort study (n=2009 households) recurring phone surveys from 2020 2022 assess knowledge, attitudes and practices. Vaccine questions were added in 2021 (n=1117) (n=1121) rounds.Five informal settlements Nairobi, Kenya.Individuals 2009 households included.Respondents...
In resource-constrained settings, Community Health Workers (CHWs) are the first point of contact between communities and health system, as providers maternal newborn services. However, little is known quality community-based postnatal care (PNC). We assessed content PNC provided by CHWs women's experiences in two Kenyan counties.We used a cross-sectional, mixed methods design to examine services CHWs. Trained observers attended home visits assess technical using 25-item checklist covering...
Maternal PM 2.5 exposures in informal settlements Nairobi exceeded WHO air quality targets, with low-quality cooking fuel use identified as the most important non-ambient source.