A5007358726- Orbital Angular Momentum in Optics
- Photonic and Optical Devices
- Advanced Fiber Laser Technologies
- Toxic Organic Pollutants Impact
- Mechanical and Optical Resonators
- Quantum Information and Cryptography
- Pharmaceutical and Antibiotic Environmental Impacts
- Metabolomics and Mass Spectrometry Studies
- Effects and risks of endocrine disrupting chemicals
- Environmental Toxicology and Ecotoxicology
- Microplastics and Plastic Pollution
- Metamaterials and Metasurfaces Applications
- Gut microbiota and health
- Nonlinear Photonic Systems
- Environmental Chemistry and Analysis
- Per- and polyfluoroalkyl substances research
- Plasmonic and Surface Plasmon Research
- Dermatology and Skin Diseases
- Dental Erosion and Treatment
- Fish Ecology and Management Studies
- Quantum Mechanics and Non-Hermitian Physics
- Isotope Analysis in Ecology
- Medicinal plant effects and applications
- Exercise and Physiological Responses
- Time Series Analysis and Forecasting
University of California, San Diego
2022-2025
University of Montana
2022-2025
University of Washington
2019-2023
University of Pennsylvania
2020-2023
Center for Urban Waters
2019-2023
Guangdong University of Technology
2023
California University of Pennsylvania
2021-2022
University of Science and Technology of China
2019-2022
Peking University
2016-2019
Seattle University
2019
In U.S. Pacific Northwest coho salmon (
Stormwater exposure can cause acute mortality of coho salmon (Oncorhynchus kisutch), and 6PPD-quinone (6PPD-Q) was identified as the primary causal toxicant. Commercial standards 6PPD-Q recently became available; their analysis highlighted a systematic high bias in prior reporting concerning 6PPD-Q. A commercial standard used to re-confirm toxicity estimates juvenile develop liquid chromatography-tandem mass spectrometry analytical method for quantification. Peak area responses were ∼15...
While a recent toxicological study has shown that organophosphorus flame retardants (OPFRs) may disrupt sphingolipid homeostasis, epidemiologic evidence is currently lacking. In this study, total of 257 participants were recruited from Shenzhen, China. Eleven OPFRs for the first time simultaneously determined in human blood samples by ultraperformance liquid chromatography and tandem mass spectrometry. Six OPFRs, tributyl phosphate (TNBP), 2-ethylhexyl diphenyl (EHDPP),...
This study used suspect and nontarget screening with high-resolution mass spectrometry to characterize the occurrence of contaminants emerging concern (CECs) in nearshore marine environment Puget Sound (WA). In total, 87 non-polymeric CECs were identified; those confirmed reference standards (45) included pharmaceuticals, herbicides, vehicle-related compounds, plasticizers, flame retardants. Eight polyfluoroalkyl substances detected; perfluorooctanesulfonic acid (PFOS) concentrations as high...
Transformation products (TPs) originating within tire tread wear particles (TWPs) are likely pervasive contaminants of roadway environments although their formation, fate, and risks poorly characterized. Here, we investigated TP formation occurring during heterogeneous reaction gas-phase ozone with the common rubber antioxidant 6PPD (N-(1,3-dimethylbutyl)-N′-phenyl-p-phenylenediamine); exposures included both pure compound TWP rubbers. Oxidative transformation occurred ozonation (∼360 ppbv),...
6PPD, a tire rubber antioxidant, poses substantial ecological risks because it can form highly toxic quinone transformation product (TP), 6PPD-quinone (6PPDQ), during exposure to gas-phase ozone. Important data gaps exist regarding the structures, reaction mechanisms, and environmental occurrence of TPs from 6PPD ozonation. To address these gaps, ozonation was conducted over 24–168 h were characterized using high-resolution mass spectrometry. The probable structures proposed for 23 with 5...
Recently, roadway releases of
The rubber antioxidant 6PPD has gained significant attention due to its highly toxic transformation product, 6PPD-quinone (6PPDQ). Despite their detection in urines of pregnant women, the placental transfer and developmental toxicity 6PPDQ are unknown. Here, we treated C57Bl/6 mice with 4 mg/kg or investigate urine excretion transfer. Female male exhibited sex difference profiles 6PPDQ. Urine concentrations were one order magnitude lower than those 6PPD, suggesting higher bioaccumulation In...
We here report chemical characteristics relevant to the fate and transport of recently discovered environmental toxicant 6PPD-quinone (2-((4-methylpentan-2-yl)amino)-5-(phenylamino)cyclohexa-2,5-diene-1,4-dione or “6PPDQ”).
Despite the increasing use and discharge of novel brominated flame retardants, little information is available about their trophodynamics in aquatic food web, subsequent relationships to compound metabolism. In this study, concentrations 2,4,6-tribromophenyl allyl ether (ATE), 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane (TBECH), tetrabromo-o-chlorotoluene (TBCT), pentabromobenzyl acrylate (PBBA), 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE), bis(2-ethylhexyl)-3,4,5,6-tetrabromo-phthalate...
Supersymmetric switch-on A common route to enhancing the output light from a laser system is couple multiple lasers form an array. However, crosstalk and interference between different modes of individual are generally detrimental performance, leading instabilities, could ultimately be damaging cavities. Qiao et al. worked with mathematical framework supersymmetry, theory developed in high-energy physics attempt describe makeup properties particles, design stable two-dimensional Based on...
On-chip integrated laser sources of structured light carrying fractional orbital angular momentum (FOAM) are highly desirable for the forefront development optical communication and quantum information-processing technologies. While vortex beam generators have been previously demonstrated in different settings, ultrafast control sweep FOAM with low-power control, suitable high-speed computing, remains challenging. Here we demonstrate fast from a semiconductor microlaser based on transient...
Abstract Even though raw mass spectrometry data is information rich, the vast majority of underutilized. The ability to interrogate these rich datasets handicapped by limited capability and flexibility existing software. We introduce Mass Spec Query Language (MassQL) that addresses issues enabling an expressive set patterns be queried directly from data. MassQL open-source query language for flexible spectrometer manufacturer-independent mining MS envision flexibility, scalability, ease use...
Coherent conversion of microwave and optical photons can significantly expand the capabilities information processing communications systems. Here, we experimentally demonstrate microwave-to-optical frequency in a magneto-optical whispering gallery mode microcavity. By applying magnetic field parallel to microsphere equator, intracavity will be modulated when magnon is excited by drive, leading via Stokes anti-Stokes scattering processes. The observed single-sideband phenomenon indicates...
Understanding the distribution of hundreds thousands plant metabolites across kingdom presents a challenge. To address this, we curated publicly available LC-MS/MS data from 19,075 extracts and developed plantMASST reference database encompassing 246 botanical families, 1,469 genera, 2,793 species. This taxonomically focused facilitates exploration plant-derived molecules using tandem mass spectrometry (MS/MS) spectra. tool will aid in drug discovery, biosynthesis, (chemo)taxonomy,...
ABSTRACT Skin microbiome can be altered in patients with atopic dermatitis (AD). An understanding of the changes from healthy to skin help develop new targets for treatment by identifying microbial and molecular biomarkers. This study investigates metabolome adult subjects lesion (ADL) non-lesion (ADNL) AD 16S rRNA gene sequencing mass spectrometry, respectively. Samples showed alterations diversity composition microbiome, ADL having greatest divergence. Staphylococcus species, especially S....
Oligomeric organophosphorus flame retardants (o-OPFRs) are extensively used as substitutes for decabromodiphenyl ether. However, little is currently known about their occurrence in aquatic environments, bioaccumulation, or trophic transfer. In this study, concentrations of two o-OPFRs, bisphenol A bis(diphenyl phosphate) (BPA-BDPP) and 1,3-phenylene (PBDPP), were measured water, sediment food web organisms (plankton, invertebrates, fishes) from Taihu Lake, China. BPA-BDPP was detected the...
Light carries both spin angular momentum (SAM) and orbital (OAM), which can be used as potential degrees of freedom for quantum information processing. Quantum emitters are ideal candidates towards on-chip control manipulation the full SAM–OAM state space. Here, we show coupling a spin-polarized emitter in monolayer <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"> <mml:mrow class="MJX-TeXAtom-ORD"> <mml:msub> <mml:mi mathvariant="normal">W</mml:mi>...
Public untargeted metabolomics data is a growing resource for metabolite and phenotype discovery; however, accessing utilizing these across repositories pose significant challenges. Therefore, we've developed pan-repository universal identifiers harmonized cross-repository metadata. This novel ecosystem facilitates discovery by integrating diverse sources from public including MetaboLights, Metabolomics Workbench, GNPS/MassIVE. Our approach simplifies handling unlocks previously inaccessible...