Adam C. Levine
A5004897644- Disaster Response and Management
- Viral Infections and Outbreaks Research
- Trauma and Emergency Care Studies
- Viral gastroenteritis research and epidemiology
- Emergency and Acute Care Studies
- Child Nutrition and Water Access
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Global Maternal and Child Health
- SARS-CoV-2 and COVID-19 Research
- Health and Conflict Studies
- Respiratory viral infections research
- Global Health and Surgery
- Climate Change and Health Impacts
- COVID-19 Impact on Reproduction
- Sepsis Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Vaccine Coverage and Hesitancy
- Migration, Health and Trauma
- Mobile Health and mHealth Applications
- Long-Term Effects of COVID-19
- Injury Epidemiology and Prevention
- Viral Infections and Vectors
- Clostridium difficile and Clostridium perfringens research
- Food Security and Health in Diverse Populations
Brown University
2016-2025
New York University
2012-2025
Rhode Island Hospital
2010-2024
International Medical Corps
2012-2023
John Brown University
2018-2023
Boston Medical Center
2022
NorthShore University HealthSystem
2022
Providence College
2010-2022
Hasbro Children's Hospital
2018-2022
University of Georgia
2022
Although several experimental therapeutics for Ebola virus disease (EVD) have been developed, the safety and efficacy of most promising therapies need to be assessed in context a randomized, controlled trial.
As portability and durability improve, bedside, clinician-performed ultrasound is seeing increasing use in rural, underdeveloped parts of the world. Physicians, nurses medical officers have demonstrated ability to perform interpret a large variety exams, growing body literature supports point-of-care developing nations. We review, by region, existing support world training guidelines currently use, highlight indications for emergency suggest future directions bedside research improve...
Polyclonal convalescent plasma may be obtained from donors who have recovered coronavirus disease 2019 (Covid-19). The efficacy of this in preventing serious complications outpatients with recent-onset Covid-19 is uncertain.
The quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) score has not been well-evaluated in low- and middle-income countries (LMICs). To assess the association of qSOFA with excess hospital death among patients suspected infection LMICs to compare systemic inflammatory response syndrome (SIRS) criteria. Retrospective secondary analysis 8 cohort studies 1 randomized clinical trial from 2003 2017. This study included 6569 hospitalized adults emergency departments, inpatient...
Acute gastroenteritis develops in millions of children the United States every year, and treatment with probiotics is common. However, data to support use this population are limited.We conducted a prospective, randomized, double-blind trial involving 3 months 4 years age acute who presented one 10 U.S. pediatric emergency departments. Participants received 5-day course Lactobacillus rhamnosus GG at dose 1×1010 colony-forming units twice daily or matching placebo. Follow-up surveys were for...
The ongoing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants severely limits available effective monoclonal antibody therapies. Effective drugs are also supply limited. COVID-19 convalescent plasma (CCP) qualified for high levels effectively reduces immunocompetent outpatient hospitalization. Food and Drug Administration currently allows CCP the immunosuppressed. Viral-specific in can range 10- to 100-fold between donors, unlike uniform viral-specific...
Cytokines and chemokines play a critical role in the response to infection vaccination. We aimed assess longitudinal association of COVID-19 vaccination with cytokine chemokine concentrations trajectories among people SARS-CoV-2 infection. In this longitudinal, prospective cohort study, blood samples were used from participants enrolled multi-centre randomised trial assessing efficacy convalescent plasma therapy for ambulatory COVID-19. The was conducted 23 outpatient sites USA. (aged ≥18...
Abstract Objectives: The objective of this study was to determine the test characteristics for two different ultrasound (US) measures severe dehydration in children (aorta inferior vena cava [IVC] ratio and IVC inspiratory collapse) one clinical measure (the World Health Organization [WHO] scale). Methods: authors enrolled a prospective cohort presenting with diarrhea and/or vomiting three rural Rwandan hospitals. Children were assessed clinically using WHO scale then underwent US by second...
Background The Rwanda Human Resources for Health Program (HRH Program) is a 7-year (2012-2019) health professional training initiative led by the Government of with goals large, diverse, and competent workforce strengthening capacity academic institutions in Rwanda. Methods data this organizational case study was collected through official reports from Ministry (MoH) 22 participating US institutions, databases MoH College Medicine Sciences (CMHS) Rwanda, surveys completed co-authors. Results...
Abstract Background The efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) convalescent plasma (CCP) for preventing infection in exposed, uninfected individuals is unknown. CCP might prevent when administered before symptoms or laboratory evidence infection. Methods This double-blinded, phase randomized, controlled trial (RCT) compared the and safety prophylactic high titer (≥1:320 by Euroimmun ELISA) with standard plasma. Asymptomatic participants aged ≥18 years close...
Despite receiving less attention than high-income countries, low- and middle-income countries (LMICs) experienced more 85% of global excess deaths during the first two years COVID-19 pandemic. Due to unprecedented speed scale pandemic, which placed large demands on government capacity, many LMICs relied civil society organizations (CSOs) assist in implementing response programs. Yet few studies have examined critical role CSOs played mitigating effects pandemic low resource settings. This...
<h3>ABSTRACT</h3> <h3>Background:</h3> Between 2008 and 2011, Rwanda introduced integrated community case management (iCCM) of childhood illness nationwide. Community health workers in each Rwanda9s nearly 15,000 villages were trained iCCM equipped for empirical diagnosis treatment pneumonia, diarrhea, malaria; malnutrition surveillance; comprehensive reporting referral services. <h3>Methods:</h3> We used data from the information system (HMIS) to calculate monthly all-cause under-5...
Objective To prospectively validate three popular clinical dehydration scales and overall physician gestalt in children with vomiting or diarrhea relative to the criterion standard of percent weight change rehydration. Methods We enrolled a non-consecutive cohort ≤ 18 years age an acute episode vomiting. Patient weight, scale variables impression, gestalt, were recorded before after fluid resuscitation emergency department upon hospital discharge. The from presentation discharge was used...
Injury accounts for 9.6% of the global mortality burden, disproportionately affecting those living in low- and middle-income countries. In an effort to improve trauma care Rwanda, Ministry Health developed a prehospital service, Service d'Aide Médicale Urgente (SAMU), established emergency medicine training program. However, little is known about patients receiving or their outcomes. The objective was develop linked prehospital–hospital database evaluate patient characteristics, mechanisms...
ABSTRACT BACKGROUND The efficacy of polyclonal high titer convalescent plasma to prevent serious complications COVID-19 in outpatients with recent onset illness is uncertain. METHODS This multicenter, double-blind randomized controlled trial compared the and safety SARS-CoV-2 placebo control symptomatic adults ≥18 years positive for regardless risk factors disease progression or vaccine status. Participants symptom within 8 days were enrolled, then transfused subsequent day. measured primary...
A bstract We study the defect operator product expansion (OPE) of displacement operators in free and interacting conformal field theories using replica methods. show that as n approaches 1 a contact term can emerge when OPE contains twist d − 2. For general states we give evidence only possibility is from becomes stress tensor → limit. This implies quantum null energy condition (QNEC) always saturated for CFTs with gap. As check, independently large class near vacuum states, second variation...
Approximately 20% of individuals infected with SARS-CoV-2 experienced long-term health effects, as defined PCC. However, it is unknown if there are any early biomarkers associated PCC or whether intervention treatments may decrease the risk In a secondary analysis randomized clinical trial, this study demonstrates that among outpatients SARS-CoV-2, increased IL-6 at time infection odds addition, treated early, within 5 days symptom onset, COVID-19 convalescent plasma, was trend for decreased...