A5036308677- Animal Virus Infections Studies
- Viral Infections and Immunology Research
- Viral gastroenteritis research and epidemiology
- Crystallization and Solubility Studies
- Trace Elements in Health
- Analytical Chemistry and Chromatography
- MicroRNA in disease regulation
- Intracerebral and Subarachnoid Hemorrhage Research
- RNA Interference and Gene Delivery
- Parasites and Host Interactions
- Natural product bioactivities and synthesis
- Helminth infection and control
- Electrocatalysts for Energy Conversion
- Immune Response and Inflammation
- Graphene and Nanomaterials Applications
- Hepatitis C virus research
- Synthesis and Biological Evaluation
- Reproductive System and Pregnancy
- Acute Ischemic Stroke Management
- Research on Leishmaniasis Studies
- Histone Deacetylase Inhibitors Research
- Advanced biosensing and bioanalysis techniques
- Antimicrobial Peptides and Activities
- Immunotherapy and Immune Responses
- Extracellular vesicles in disease
Guangdong Academy of Sciences
2023-2025
Southern Medical University
2012-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Nanfang Hospital
2012-2025
Lanzhou University
2016-2024
Lanzhou University Second Hospital
2017-2024
Anhui Science and Technology University
2023-2024
Anhui University of Science and Technology
2023-2024
Hubei University of Chinese Medicine
2024
Guangdong Academy of Medical Sciences
2024
Abstract Electric fields have been proposed as having a distinct ability to catalyze chemical reactions through the stabilization of polar or ionic intermediate transition states. Although field-assisted catalysis is being researched, in solution using electric remains elusive and understanding mechanisms such sparse. Here we show that an field can cis-to-trans isomerization [3]cumulene derivatives solution, scanning tunneling microscope. We further external alter thermodynamics inhibiting...
D-phenothrin is one of the most popular pyrethroid insecticides for its broad spectrum and high insecticidal activity. However, continuous use has resulted in serious environmental contamination raised public concern about impact on human health. Biodegradation never been investigated metabolic behaviors remain unknown. Here, a novel bacterial strain P31 was isolated from active sludge, which completely degraded (100%) at 50 mg·L-1 72 h. Based morphology, 16S rRNA gene Biolog tests,...
Mesenchymal stem cells (MSCs), with the capacity for self-renewal and differentiation into multiple cell types, exhibit property of homing towards tumor sites immunosuppression have been used as tumor-tropic vectors therapy. However, few studies investigated underlying molecular mechanisms that link MSCs to targeted cells. In this study, we elucidated inhibitory effects human bone marrow mesenchymal (hBMSCs) on glioma U251 using a co-culture system in vitro. The anti-tumor activity...
Background Iron overload is recognized as a new pathogenfor osteoporosis. Various studies demonstrated that iron could induce apoptosis in osteoblasts and osteoporosis vivo. However, the exact molecular mechanisms involved overload-mediated induction of has not been explored. Purpose In this study, we attempted to determine whether mitochondrial apoptotic pathway iron-induced osteoblastic cell death investigate beneficial effect N-acetyl-cysteine (NAC) cytotoxicity. Methods The MC3T3-E1 line...
Protein phosphatase 2A (PP2A) negatively regulates tumorigenic signaling pathways, in part, by supporting the function of tumor suppressors like p53. The PP2A methylesterase PME-1 limits activity demethylating its catalytic subunit. Here, we report finding that overexpression correlates with increased cell proliferation and invasive phenotypes endometrial adenocarcinoma cells, where it helps maintain activated ERK Akt inhibiting PP2A. We obtained evidence could bind regulate protein 4 (PP4),...
The purpose of this study was to identify possible association between noncontrast computed tomography (NCCT)-based radiomics features perihematomal edema (PHE) and poor functional outcome at 90 days after intracerebral hemorrhage (ICH) develop a NCCT-based radiomics-clinical nomogram predict 90-day outcomes in patients with ICH.In multicenter retrospective study, 107 were extracted from 1098 NCCT examinations obtained ICH. There 652 men 446 women mean age 60 ± 12 (SD) years (range: 23-95...
To examine the factor structure and psychometric properties of Patient Health Questionnaire for Adolescents (PHQ-A) in Chinese children adolescents with major depressive disorder (MDD).
The extensive application of graphene nanosheets (GNSs) has raised concerns over risks to sensitive species in the aquatic environment. humic acid (HA) corona is traditionally considered reduce GNSs toxicity. Here, we evaluate effect sorbed HA (GNSs-HA) on toxicity Gram positive Bacillus tropicus. Contrary previous data, GNSs-HA exhibits greater compared GNSs. Multi-omics combined with bioassays and electrochemical methods reveals disrupt oxidative phosphorylation by causing physical...
Abstract Signal decomposition plays a crucial role in the early diagnosis of impact faults mechanical equipment. However, existing time-frequency methods often overlook aggregational distribution characteristics impacts time domain and exhibit low computational efficiency when processing multi-source signals. To address these limitations, this study proposes reassigned adaptive (TFR-IAD) method, building upon variational (VTFAD) framework for multi-impact signal analysis. The TFR-IAD method...
Abstract A novel facultative psychrotroph (strain CBS-1), which accumulates poly-β-hydroxybutyrate (PHB), was isolated from soil samples taken Changbai Mountain, China. Phylogenetic analysis based on 16S rRNA sequence data and Biolog identified strain CBS-1 as Pseudomonas mandelii . Transmission electron micrographs revealed abundant electron-transparent intracellular granules. 1 H-nuclear magnetic resonance that the granules were composed of PHB. P grew optimally at 20°C. When cultured...