A5078128649- Aquaculture disease management and microbiota
- Immune Response and Inflammation
- Genomics and Phylogenetic Studies
- MicroRNA in disease regulation
- Genetic Mapping and Diversity in Plants and Animals
- Cancer-related molecular mechanisms research
- Chromosomal and Genetic Variations
- Immune Cell Function and Interaction
- interferon and immune responses
- T-cell and B-cell Immunology
- Invertebrate Immune Response Mechanisms
- Tea Polyphenols and Effects
- Plant biochemistry and biosynthesis
- Antibiotic Resistance in Bacteria
- Synthesis and biological activity
- Synthesis and Characterization of Heterocyclic Compounds
- Lanthanide and Transition Metal Complexes
- Identification and Quantification in Food
- Drug Transport and Resistance Mechanisms
- NF-κB Signaling Pathways
- Pediatric Hepatobiliary Diseases and Treatments
- RNA Interference and Gene Delivery
- Microbial Metabolism and Applications
- Cell death mechanisms and regulation
- Ichthyology and Marine Biology
South China Agricultural University
2020-2025
Huazhong Agricultural University
2018-2025
Shanghai Clinical Research Center
2025
Shanghai Jiao Tong University
2025
Shanghai First People's Hospital
2025
Liaoning Normal University
2015-2024
Guangzhou Medical University
2024
Dalian Polytechnic University
2020-2024
Nanjing University of Aeronautics and Astronautics
2023
Guangxi Institute of Oceanography
2022
Tea is the world's oldest and most popular caffeine-containing beverage with immense economic, medicinal, cultural importance. Here, we present first high-quality nucleotide sequence of repeat-rich (80.9%), 3.02-Gb genome cultivated tea tree Camellia sinensis. We show that an extraordinarily large size resulted from slow, steady, long-term amplification a few LTR retrotransposon families. In addition to recent whole-genome duplication event, lineage-specific expansions genes associated...
Significance Asian rice ( Oryza sativa ) is among the world’s most important crops. The genus has become a model for study of plant genome structure, function, and evolution. We have undertaken de novo, full-genome sequence analysis five diploid AA-genome species that are closely related to O. . These native quite different environments, representing four continents, thus exhibiting very adaptations. Our studies identify specific genetic changes, in both gene copy number degree diversifying...
Arterial calcification is a major complication of cardiovascular disease. Oestrogen replacement therapy in postmenopausal women associated with lower levels coronary artery calcification, but its mechanism action remains unclear. Here, we show that oestrogen inhibits the osteoblastic differentiation vascular smooth muscle cells (VSMCs) vitro and arterial vivo by promoting autophagy. Through electron microscopy, GFP-LC3 redistribution, immunofluorescence analyses as well measurement...
Lettuce is a globally important leafy vegetable that exhibits diverse horticultural types and strong population structure, which complicates genetic analyses. To address this challenge, we develop the first multi-parent, advanced generation inter-cross (MAGIC) for lettuce using 16 founder lines. Whole-genome sequencing of lines 381 inbred progeny reveal minimal enabling informative genome-wide association studies (GWAS). GWAS MAGIC identifies numerous loci associated with key agricultural...
Livestock farms are generally considered to be the important source of antibiotic resistance genes (ARGs). It is explore spread ARGs reduce their harm. This study analyzed 13 belonging 7 types in 68 samples layer manure including different stages breeding, fertilizer, and soil from 9 laying hen Guangdong Province. The detection rate was extremely high at farm (100%), fertilizer (> 95%). log counts (3.34-11.83 copies/g) were significantly higher than those (3.45-9.80 (0-7.69 copies/g). In...
Chronic psychological stress has been shown to adversely impact immune system functions and compromise host defenses against various infections. However, the underlying mechanisms remain elusive. Recent studies have demonstrated that myeloid-derived suppressor cells (MDSCs) play an important role in regulating immunity. It is of interest explore whether or not chronic plays immunosuppressive partially by inducing MDSCs accumulation. In this work, we report led accumulation CD11b+Gr1+ bone...
Abstract The reissner lamprey Lethenteron reissneri , belonging to the class Cyclostomata, serves as a bridge between invertebrates and jawed vertebrates, is considered sister group of vertebrates. However, despite this evolutionary significance, genetic mechanisms underlying adaptive evolution lineage remain unclear. Here, we assembled 1.06 Gb chromosome‐level draft genome L. with 72 chromosomes (ranging in length from 4.5 Mb 25.9 Mb) scaffold N50 13.23 Mb. Genome quality comparisons...
A 32-metal Cd–Tb nanocluster with enhanced visible luminescence was constructed by the introduction of energy transfer donors (1,4-BDC) for potential bioimaging applications.
Two types of Zn–Ln nanoscale complexes were constructed using Schiff base ligands, and the 12-metal Zn–Eu complex shows interesting luminescent sensing metal cations.
Abstract Asian cultivated rice is believed to have been domesticated from a wild progenitor, Oryza rufipogon , offering promising sources of alleles for world improvement. Here we first present high-quality chromosome-scale genome the typical O. . Comparative genomic analyses sativa and its two progenitors, nivara identified many dispensable genes functionally enriched in reproductive process. We detected millions variants, which large-effect mutations could affect agronomically relevant...
Abstract Our previous study shows that Coptotermes formosanus (Blattodea: Rhinotermitidae) preferred to stay on filter paper treated with ethyl 2,4‐dioxovalerate, a metabolite in the soil fungus Trichoderma virens . Here, we hypothesized adding 2,4‐dioxovalerate sand could trigger aggregation and tunneling preferences of C. improve effectiveness liquid termiticide. In aggregation‐choice tests, significantly more termites were found on/in blocks containing (250 µ g/g) than untreated...
phage therapy is a promising approach for infections caused by drug-resistant bacteria; this study evaluated the impact of pre-exposure to particles on subsequent therapy. Mice were exposed intradermally (i.d.) Staphylococcus aureus wide-host-range JD007, member Myoviridae family. phage-specific antibodies detected using ELISA. infected with S. in same way establish dermal abscess model, and then efficacy mice pre-exposed JD007 was evaluated. could induce their specific IgM IgG. levels...
In previous research, we found that cell secretion from the adult lamprey supraneural body tissues possesses cytocidal activity against tumor cells, but protein with was unidentified. A novel immune (LIP) as defense molecule first purified and identified in jawless vertebrates (cyclostomes) using hydroxyapatite column Q Sepharose Fast Flow column. After LIP stimulation, morphological changes of cells were analysed measured whether vivo or vitro. induces remarkable including blebbing,...
Abstract African wild rice Oryza longistaminata , one of the eight AA‐ genome species in genus possesses highly valued traits, such as rhizomatousness for perennial breeding, strong tolerance to biotic and abiotic stresses, high biomass production on poor soils. To obtain high‐quality reference O. we employed a hybrid assembly approach through incorporating Illumina PacBio sequencing datasets. The final comprised only 107 scaffolds was approximately ∼363.5 Mb, representing ∼92.7% estimated...
In this study, we firstly determined the complete mitogenome of Japanese topeshark (Hemitriakis japonica), which belong to family Triakidae and was assessed as Endangered A2d on IUCN Red List in 2021. The is 17,301 bp long, has a high AT content (60.0%), contains 13 protein-coding genes, 22 tRNA 2 rRNA control region specially 594 bp-long non-coding between Cytb gene tRNA-Thr gene. novel share sequence similarity with segments former latter so it recognized duplication remnant. addition,...