A5054652495- Dialysis and Renal Disease Management
- Blood Pressure and Hypertension Studies
- Central Venous Catheters and Hemodialysis
- Heart Rate Variability and Autonomic Control
- Chronic Kidney Disease and Diabetes
- Muscle and Compartmental Disorders
- Acute Kidney Injury Research
- Vascular Procedures and Complications
- Hormonal Regulation and Hypertension
- Health Systems, Economic Evaluations, Quality of Life
- Renal and Vascular Pathologies
- Cardiovascular Health and Disease Prevention
- Sodium Intake and Health
- Heart Failure Treatment and Management
- Cardiovascular Syncope and Autonomic Disorders
- Advanced MRI Techniques and Applications
- Parathyroid Disorders and Treatments
- Pharmacological Effects and Toxicity Studies
- MRI in cancer diagnosis
- Renal function and acid-base balance
- Erythropoietin and Anemia Treatment
- Iron Metabolism and Disorders
- Diabetes Treatment and Management
- Electrolyte and hormonal disorders
- Renal Diseases and Glomerulopathies
University Medical Center Utrecht
2016-2025
Utrecht University
2014-2024
Target (United States)
2023-2024
Radiance Technologies (United States)
2022-2023
University of Zurich
2023
Amsterdam UMC Location Vrije Universiteit Amsterdam
2016-2020
Karolinska Institutet
2019
Universitätsklinikum Würzburg
2018
Hennepin County Medical Center
2018
University of Minnesota
2018
In patients with ESRD, the effects of online hemodiafiltration on all-cause mortality and cardiovascular events are unclear. this prospective study, we randomly assigned 714 chronic hemodialysis to postdilution (n=358) or continue low-flux (n=356). The primary outcome measure was mortality. main secondary endpoint a composite major events, including death from causes, nonfatal myocardial infarction, stroke, therapeutic coronary intervention, carotid vascular amputation. After mean 3.0 years...
Inhibition of angiotensin-converting enzyme (ACE) reduces the risk cardiovascular problems in patients with chronic renal failure. This effect may be due part to a decrease sympathetic nervous activity, but no direct evidence such an action is available.
Vascular access standards are predominantly based on older, single-center reports; however, the hemodialysis population has changed dramatically and primary arteriovenous fistula failure is a huge problem. This prospective, multicenter study used standardized definitions to analyze patency rates potential risk factors that affect functional late functionality.Eleven centers participated in guidelines implementation program. All new permanent vascular accesses were included. Patency patency,...
Globally, the number of patients undergoing maintenance dialysis is increasing, yet throughout world there significant variability in practice initiating dialysis. Factors such as availability resources, reasons for starting dialysis, timing initiation, patient education and preparedness, modality access, well varied "country-specific" factors significantly affect experiences outcomes. As burden end-stage kidney disease (ESKD) has increased globally, also been a growing recognition...
eCrCl (mL/min) a Warfarin Apixaban b Dabigatran Edoxaban c Rivaroxaban >95 Adjusted dose (INR 2-3) 5 mg b.i.d.150 b.i.d.60 QD d 20 51-95 31-50 b.i.d.(eCrCl cut-off 25 mL/min) 150 b.i.d. or 110 e 30 15 INR, international normalized ratio.a Cockcroft-Gault estimated creatinine clearance (eCrCl).b modification from to 2.5 b.i.d.if patient has any two of the following: serum > _1.5 mg/dL, age _80 years, body weight < _60 kg.c In ENGAGE-AF TIMI 48 study, was halved if 30-50 mL/min, kg,...
The general objective assigned to the EUropean DIALlysis (EUDIAL) Working Group by European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) was enhance quality of dialysis therapies in Europe broadest possible sense. Given increasing interest convective therapies, has started focusing on haemodiafiltration (HDF) therapies. Several reports suggest that those potentially improve outcomes for end-stage renal disease patients. is leader field, having introduced concept...
Several studies have suggested that patients with kidney failure may benefit from high-dose hemodiafiltration as compared standard hemodialysis. However, given the limitations of various published studies, additional data are needed.
Approximately 8–18% of all patients with high blood pressure (BP) are apparently resistant to drug treatment.1,2 In this situation, new strategies help reduce BP urgently needed but the complex pathophysiology hypertension makes search difficult. Not surprisingly in context, latest non-drug treatment which triggered controversy is catheter-based renal denervation (RDN).3,4 The method uses radiofrequency energy, or alternatively ultrasound chemical denervation, disrupt nerves within artery...
Functional renal magnetic resonance imaging (MRI) has seen a number of recent advances, and techniques are now available that can generate quantitative biomarkers with the potential to improve management kidney disease. Such sensitive changes in blood flow, tissue perfusion, oxygenation microstructure (including inflammation fibrosis), processes important range diseases including chronic However, several challenges remain move these towards clinical adoption, from technical validation...