A5044504500- Psoriasis: Treatment and Pathogenesis
- Systemic Lupus Erythematosus Research
- Atherosclerosis and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Systemic Sclerosis and Related Diseases
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Medication Adherence and Compliance
- Cardiovascular Health and Disease Prevention
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Emergency and Acute Care Studies
- Mobile Health and mHealth Applications
- Inflammatory Myopathies and Dermatomyositis
- Liver Disease Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Parasites and Host Interactions
- Sarcoidosis and Beryllium Toxicity Research
- Bladder and Urothelial Cancer Treatments
- Health, psychology, and well-being
- HIV-related health complications and treatments
- Polyomavirus and related diseases
- Cardiovascular Health and Risk Factors
- Tryptophan and brain disorders
- Healthcare Operations and Scheduling Optimization
- Kawasaki Disease and Coronary Complications
Northwestern University
2021-2025
Weill Cornell Medicine
2024
Cornell University
2024
Washington University in St. Louis
2017-2020
National Institutes of Health
2018-2019
National Heart Lung and Blood Institute
2018-2019
Saint Louis Zoo
2016
The use of biologic therapy has increased over the past decade well beyond primary autoimmune diseases. Indeed, a recent trial using an anti-IL-1beta antibody reduced second myocardial infarction (MI) in those who have had MI. Psoriasis is chronic inflammatory disease often treated with biologics when severe, associated risk MI, part driven by high-risk coronary plaque phenotypes computed tomography angiography (CCTA). We hypothesized that we would observe reduction inflammatory-driven...
Inflammation is critical to atherosclerosis. Psoriasis, a chronic inflammatory disease associated with early cardiovascular events and increased aortic vascular inflammation (VI), provides model study the process of atherogenesis. Fludeoxyglucose F 18 positron emission tomography/computed tomography (18F-FDG PET/CT) helps quantify VI, coronary computed angiography artery (CAD) assessment through evaluation total plaque burden (TB) noncalcified (NCB), luminal stenosis, high-risk plaques...
Comorbidities and socioeconomic barriers often limit patient adherence self-management with hemodialysis. Missed sessions, associated communication barriers, can result in emergency dialysis avoidable hospitalizations. This proof of concept study explored using a novel digital-messaging platform, EpxDialysis, to improve patient-to-dialysis center via widely available text messaging telephone technology. A randomized controlled trial was conducted through Washington University-affiliated...
Psoriasis, a chronic inflammatory skin disease associated with accelerated noncalcified coronary burden (NCB) by computed tomography angiography (CCTA), accelerates lipoprotein oxidation in the form of oxidized modified lipoproteins. A transmembrane scavenger receptor for these lipoproteins is lectinlike low-density receptor-1 (LOX-1), which has been reported to be artery disease. It unknown whether this psoriasis.To assess association between soluble LOX-1 (sLOX-1) and NCB psoriasis over...
Introduction Owing to its capacity perform remote assessments, telemedicine is rising as a new force in chronic obstructive pulmonary disease (COPD) management. We conducted an eight month randomised-controlled-trial study the effect of automated intervention on patients’ time-to-hospitalisation. Methods A total 168 patients with diagnosis COPD past 24 months were enrolled receive at primary care clinic. The treatment group received daily phone messages from system asking them report if they...
Treatment options for several chronic infectious and inflammatory conditions have expanded in recent years. This may implications evolving competing risks inflammation-associated comorbidities, including cardiovascular diseases (CVDs). Yet sparse data exist on patterns over time mortality conditions. We used from the Centers Disease Control Prevention 1999-2018 Multiple Causes of Death database to investigate CVD January 1, 1999 December 31, 2018 Specifically, we determined age-adjusted...
Background: Patient noncompliance with therapy, treatments, and appointments represents a significant barrier to improving health care delivery reducing the cost of care.One method improve therapeutic adherence is feedback loops in getting clinically acute events issues relevant clinical providers as necessary (ranging from detecting hypoglycemic for patients diabetes notifying provider when are out medications).Patients often don't know which information should prompt call their physician...
Abstract Purpose Systemic sclerosis (SSc) is an autoimmune disease that causes inflammation and fibrosis. Cardiac involvement in SSc often subclinical portends a worse prognosis. Autologous hematopoietic stem cell transplant (HSCT) improves survival but its effect on cardiac function unknown. This study aimed to assess HSCT’s mechanics SSc. Methods Participants with were identified from prospective registry, grouped according the receipt of HSCT between 2009 2018. The cohort underwent...
Antimelanoma differentiation-associated gene 5 (MDA5) dermatomyositis is a recently described disease entity that presents with distinct mucocutaneous and systemic features.1 In this case report, we describe patient anti-MDA5 who presented interstitial lung (ILD), classic cutaneous findings, acute encephalopathy.
Introduction: Serum uric acid (sUA), a known inflammosome-inducer, is associated with prospective risk of coronary artery disease in dose-dependent fashion. Psoriasis (PSO), chronic inflammatory elevated burden systemic inflammation and subclinical disease, provides reliable human model to study how sUA may relate non-calcified plaque (NCB) measured by computed tomography angiography (CCTA). Hypothesis: We hypothesized that would directly associate NCB beyond traditional cardiovascular (CV)...
Purpose: Telemedicine uses video technology to communicate visual clinical information about patients. While shown be a feasible model in pediatric transport, our institution has experienced implementation barriers the past. The purpose of this study was implement telemedicine transport at tertiary children's hospital, assess its value specific conditions and identify use. Methods: This prospective Saint Louis Children's Hospital. workflows six divisions involved (Emergency Department (ED),...
You have accessJournal of UrologyGeneral & Epidemiological Trends Socioeconomics: Quality Improvement Patient Safety II1 Apr 2016MP08-19 IMPROVING RADICAL CYSTECTOMY CARE: OUTCOMES, COMPLIANCE, AND BARRIERS TO ADOPTION FOR A NEW PROTOCOL Jacob Groenendyk, Joel Vetter, Vicky Peck, and Seth Strope GroenendykJacob Groenendyk More articles by this author , VetterJoel Vetter PeckVicky Peck StropeSeth View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2264AboutPDF ToolsAdd to...
Objective: We undertook the design and implementation of a proactive telecommunication tool, EpxEpilepsy, to more accurately frequently track seizures, thereby improving care epilepsy patients. Additionally, we present cost-benefit analysis that demonstrates its capability enable new revenue generation for providers under recent fee-for-service codes. Background: To fill in gaps between often long periods clinic visits, management revolves around self-recorded seizure diaries, which can be...