A5101542954- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Plant Molecular Biology Research
- Quantum chaos and dynamical systems
- Computational Drug Discovery Methods
- Analytical Chemistry and Chromatography
- Smart Grid Energy Management
- Research in Cotton Cultivation
- Wheat and Barley Genetics and Pathology
- Viral Infections and Immunology Research
- Fault Detection and Control Systems
- Plant Virus Research Studies
- Health, Environment, Cognitive Aging
- Power Systems and Renewable Energy
- Machine Learning in Materials Science
- Virus-based gene therapy research
- Energy Efficient Wireless Sensor Networks
- Heart Failure Treatment and Management
- Gene expression and cancer classification
- Air Quality and Health Impacts
- Advanced Sensor and Control Systems
- Wireless Sensor Networks and IoT
- Analytical Methods in Pharmaceuticals
- Indoor and Outdoor Localization Technologies
- Genetic Mapping and Diversity in Plants and Animals
China Agricultural University
2021-2025
Nanjing University of Science and Technology
2021-2022
South China Agricultural University
2013-2022
Nanjing University
1996-2022
Xinjiang Medical University
2010-2022
Shanghai University of International Business and Economics
2022
Center of Hubei Cooperative Innovation for Emissions Trading System
2015-2021
Huazhong Agricultural University
2015-2021
North Carolina State University
2018-2021
Ping An (China)
2021
Abstract The R2R3-MYB is one of the largest families transcription factors, which have been implicated in multiple biological processes. There great diversity number genes different plants. However, there no report on genome-wide characterization this gene family cotton. In present study, a total 205 putative were identified cotton D genome ( Gossypium raimondii ), that are much larger than found other cash crops with fully sequenced genomes. These GrMYBs classified into 13 groups from...
Location Based Service (LBS) is one kind of ubiquitous applications whose functions are based on the locations clients. The core LBS an effective positioning system. As wireless LAN (WLAN) costs less and easy to access, using WLAN for indoor has been widely studied recently. K nearest neighbors (KNN) basic deterministic fingerprint algorithms used WLAN-based positioning. However, KNN takes all calculating estimated result, which could be improved if some selective work done those beforehand....
Plant-specific TEOSINTE-BRANCHED1/CYCLOIDEA/PCF (TCP) transcription factors play versatile functions in multiple aspects of plant growth and development. However, no systematical study has been performed cotton. In this study, we for the first time genome-wide identification expression analysis TCP factor family Gossypium raimondii. A total 38 non-redundant cotton encoding genes were identified. The divided into eleven subgroups based on phylogenetic analysis. Most within same subfamily...
Gene set analysis is a valuable tool to summarize high-dimensional gene expression data in terms of biologically relevant sets. This an active area research and numerous methods have been developed. Despite this popularity, systematic comparative studies limited scope. In study we present semi-synthetic simulation using real datasets order test compare commonly used methods. A software pipeline, Flexible Algorithm for Novel Simulation (FANGS) develops simulated based on prostate cancer...
Silicone wristbands are promising passive samplers to support epidemiological studies in characterizing exposure organic contaminants; however, investigating associated health risks remains challenging because of the latency period for many chronic diseases that take years manifest. Dogs provide valuable insights as sentinels exposure-related human disease they share similar exposures home, have shorter life spans, clinical/biological features, and closely related genomes. Here, we evaluated...
Deficits in impulse control (difficulties inhibition of a pre-potent response) are fundamental to number psychiatric disorders, but the molecular and cellular basis is poorly understood. Zebrafish offer very useful model for exploring these mechanisms, there currently lack validated procedures measuring impulsivity fish. In mammals, can be measured by examining rates anticipatory responding 5-choice serial reaction time task (5-CSRTT), continuous performance where subject reinforced upon...
Abstract TCP proteins are plant-specific transcription factors implicated to perform a variety of physiological functions during plant growth and development. In the current study, we performed for first time comprehensive analysis gene family in diploid cotton species, Gossypium arboreum , including phylogenetic analysis, chromosome location, duplication status, structure conserved motif as well expression profiles fiber at different developmental stages. Our results showed that G. contains...
Foot-and-mouth disease (FMD) is a highly contagious, severe viral illness notifiable to the World Organization for Animal Health. The causative agent, FMD virus (FMDV), replicates rapidly and efficiently inhibits host translation innate immune response it has developed multiple tactics evade defenses takes over gene expression machinery in cell. Here, we report systemic analysis of proteome phosphoproteome FMDV-infected cells. Bioinformatics suggested that FMDV infection shuts off...
Absorption, distribution, metabolism, and excretion (ADME) studies are critical for drug discovery. Conventionally, these tasks, together with other chemical property predictions, rely on domain-specific feature descriptors, or fingerprints. Following the recent success of neural networks, we developed Chemi-Net, a completely data-driven, domain knowledge-free, deep learning method ADME prediction. To compare relative performance Chemi-Net Cubist, one popular machine programs used by Amgen,...
Abstract Keymessage In this first QTL mapping study of embryo size in barley, novel and stable were identified candidate genes underlying a significant locus independent kernel based on orthologous analysis comparison the whole-genome assemblies for both parental genotypes population. Embryo, also known as germ, cereal grains plays crucial role plant development. The accounts only small portion grain weight but it is rich nutrients. Larger translates to more nutritious larger store energy...
Background: Autosomal dominant polycystic kidney disease (ADPKD) is a common, inherited nephropathy often resulting in failure. It genetically heterogeneous; along with the major genes, PKD1 and PKD2 , at least 8 others have been suggested. ALG8 pathogenic variants associated autosomal liver implicated ADPKD, while ALG9 has suggested as an ADPKD gene, but details of phenotypes penetrance are unclear. Methods: We screened >3900 families cystic kidneys and/or livers using global approaches...
qnrD, unlike other qnr genes, is mainly located on small nonconjugative plasmids. We investigated the presence of qnrD among 1,373 Enterobacteriaceae isolates in China. Twelve qnrD-positive strains were detected, and all nonsusceptible to fluoroquinolones. The complete sequence plasmids showed that determinants two with a respective size ∼4.2 2.7 k-bp. Interestingly, identification this study revealed highest prevalence Proteeae identified.
Porcine reproductive and respiratory syndrome virus (PRRSV) is a huge threat to the modern pig industry, current vaccine prevention strategies could not provide full protection against it. Therefore, exploring new anti-PRRSV urgently needed. Ginsenoside Rg1, derived from ginseng notoginseng, shown exert anti-inflammatory, neuronal apoptosis-suppressing anti-oxidant effects. Here we demonstrate Rg1-inhibited PRRSV infection both in Marc-145 cells porcine alveolar macrophages (PAMs)...
Cancer is one of the main causes death worldwide. Combination drug therapy has been a mainstay cancer treatment for decades and shown to reduce host toxicity prevent development acquired resistance. However, immense number possible combinations large synergistic space makes it infeasible screen all effective pairs experimentally. Therefore, crucial develop computational approaches predict synergy guide experimental design discovery rational therapy.We present new deep learning approach by...
Gastric cancer (stomach cancer) is the fifth most common malignancy and third leading cause of cancer‑associated mortality worldwide. Identifying gastric patients at an early curable stage disease essential if rates for this are to decrease. A non‑invasive blood‑based test that indicator risk would likely be benefit in identifying stage, such a may enhance clinical decision making. This study identified four‑gene expression signature peripheral blood samples associated with cancer. total 216...
Porcine reproductive and respiratory syndrome virus (PRRSV) suppresses the innate immune response in host, reducing delaying neutralizing antibody production against PRRSV infection promoting viral infection. Here, we aimed to assess potential of Panax notoginseng saponins (PNS) for improving exerted upon PRRSV-2-modified live (MLV) vaccine administration. Thirty piglets were randomly divided into six groups. Group 1 injected with medium 0 days post vaccination (dpv). 2 fed PNS 0–28 dpv. 3...