- Ovarian cancer diagnosis and treatment
- Gestational Trophoblastic Disease Studies
- Reproductive Biology and Fertility
- Endometrial and Cervical Cancer Treatments
- Ovarian function and disorders
- Prenatal Screening and Diagnostics
- Ectopic Pregnancy Diagnosis and Management
- Uterine Myomas and Treatments
- Cancer Risks and Factors
- Endometriosis Research and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- PARP inhibition in cancer therapy
- COVID-19 and healthcare impacts
- Cancer Immunotherapy and Biomarkers
- Intraperitoneal and Appendiceal Malignancies
- Cancer, Lipids, and Metabolism
- Renal cell carcinoma treatment
- Reproductive System and Pregnancy
- Cancer survivorship and care
- S100 Proteins and Annexins
- Economic and Financial Impacts of Cancer
- CAR-T cell therapy research
- BRCA gene mutations in cancer
- Reproductive Health and Technologies
- Acute Ischemic Stroke Management
Istituti di Ricovero e Cura a Carattere Scientifico
2004-2025
Vita-Salute San Raffaele University
2016-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2017-2024
San Raffaele University of Rome
2014-2024
IRCCS Ospedale San Raffaele
2016-2024
Mylan (Switzerland)
2017
National Research Council
2006
Casa Sollievo della Sofferenza
1997-2004
ABSTRACT Objectives The ultrasound diagnosis of placental site trophoblastic tumor (PSTT) is challenging owing to a lack pathognomonic features. Differential from other forms gestational neoplasia (GTN) critical major differences in prognosis and treatment. Doppler measurement uterine artery (UtA) pulsatility index (PI) has been proposed for the management GTN. aim this study was evaluate added value UtA‐PI during standard transvaginal (TVS) assessment, patients with PSTT as compared those...
Abstract Neutrophil-to-lymphocyte ratio (NLR) and systemic inflammatory index (SII) are prognostic factors in epithelial ovarian cancer (EOC). Their predictive value for platinum-sensitivity their role recurrent EOC unknown. A total of 375 patients were retrospectively analyzed. The correlation between baseline NLR SII, platinum-free interval (PFI) according to first line bevacizumab treatment analyzed using logistic regression analyses adjusted patient characteristics. Subsequently SII...
Evidence indicates that different pathways of malignant degeneration underlie the development endometriosis-associated ovarian tumors endometrioid and clear cell histotypes. The aim this study was to compare data from patients affected by these two histotypes investigate hypothesis a dichotomy in histogenesis tumors. Clinical tumor characteristics 48 who were diagnosed with either pure cancer mixed endometrioid–clear arising endometriosis (ECC, n = 22) or (EAEOC, 26) compared. A previous...
BReast CAncer (BRCA) genes are extensively studied in the context of fertility and reproductive aging. BRCA proteins part DNA repair Fanconi anemia (FA)/BRCA pathway, which more than 20 implicated. According to gene is mutated interactions lost owing mutation, carriers patients with monoallelic or biallelic FA/BRCA mutations exhibit very different phenotypes, from overt FA cancer predisposition no pathological implications. The effect so far neglected non-BRCA on also deserves...
Abstract Purpose This research aimed to investigate the socio-demographic, clinical, and psychological variables predictive of a greater functioning quality life in patients with gynecological cancer after their first cycle carboplatin taxol-based chemotherapy. Methods The sample present consisted 104 patients. European Organization on Research Treatment Cancer QLQ-C30, State-Trait Anxiety Inventory-Form Y, Multidimensional Scale Perceived Social Support were administered each participant....
<h3>Objectives</h3> Gestational trophoblastic neoplasia affects women of reproductive age and is usually treated by chemotherapy. Major concerns related to chemotherapy in young are the possible infertility, risk early menopause, teratogenic effects on subsequent pregnancies. The study9s aim was analyze menstrual outcomes with single-agent versus multiagent for gestational neoplasia. <h3>Methods</h3> One-hundred fifty-one patients were treated. Seventy-six older than 45 years, a placental...